This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Cases of the fungal disease candidiasis in infants have been increasing over the past two decades, but our understanding of the behavior and evolution of Candida spp. outside laboratory models has been lacking. Researchers assembled new C. albicans and C. parapsilosis genomes using data from premature infant feces, hospital surfaces, clinical samples, and non-hospital environmental samples. Relative to an existing reference genome, the C. parapsilosis genomes analyzed had genomic “hotspots” of single nucleotide variants, and the C. parapsilosis genomes from premature infants had hotspots that matched hospital and subway surface samples, which may suggest a common ancestor. The researchers also analyzed a microbial gene expression time course in one infant being treated for Candida infection. The in situ transcriptomic profiles were highly variable relative to cultured C..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
Economists can’t agree on whether investors and markets are rational and efficient, …
Economists can’t agree on whether investors and markets are rational and efficient, as modern financial theory assumes, or irrational and inefficient, as behavioral economists believe. Drawing on psychology, evolutionary biology, neuroscience, artificial intelligence, and other fields, Prof. Lo cuts through the debate in this course with a new framework—the Adaptive Markets Hypothesis—in which rationality and irrationality coexist. Topics:
Introduction and Financial Orthodoxy Rejecting the Random Walk and Efficient Markets Behavioral Biases and Psychology The Neuroscience of Decision-Making Evolution and the Origin of Behavior The Adaptive Markets Hypothesis Hedge Funds: The Galapagos Islands of Finance Applications of Adaptive Markets The Financial Crisis Ethics and Adaptive Markets The Finance of the Future and the Future of Finance
As part of the Open Learning Library (OLL), this course is free to use. You have the option to sign up and enroll if you want to track your progress, or you can view and use all the materials without enrolling. Resources on OLL allow learners to learn at their own pace while receiving immediate feedback through interactive content and exercises.
Finches on the Galapagos Islands have evolved to exploit almost every possible …
Finches on the Galapagos Islands have evolved to exploit almost every possible niche. This diagram shows the range of food sources available on the island and the different beak shapes adapted to exploit each of them.
En este curso el estudiante perfeccionará su comunicación oral y escrita mediante …
En este curso el estudiante perfeccionará su comunicación oral y escrita mediante el estudio y la discusión de temas relacionados al impacto social y cultural de la ciencia y la tecnología en ciertas sociedades hispanas. Algunos de los temas a tratar son los efectos de los cambios tecnológicos en la estructura familiar y comunitaria, en las relaciones entre los sexos, en la identidad personal y cultural, en el mundo natural y en los sistemas de valores, la religión, la educación y el trabajo. También se examinan y discuten diversas actitudes hacia la innovación tecnológica y científica así como las ramificaciones éticas de las decisiones tecnológicas.
This course considers films spanning the entire career of pioneering Spanish filmmaker …
This course considers films spanning the entire career of pioneering Spanish filmmaker Luis Buñuel (1900–1983), from his silent surrealist classic of 1929, Un perro andaluz, to his last film, Ese oscuro objeto del deseo (1977). We pay special attention to his Mexican period, in exile, and the films he made in, and about, Spain, including his work in documentary. It explores Buñuel's early friendship with painter Salvador Dalí and poet Federico García Lorca, surrealist aesthetics, the influence of Freud's ideas on dreams and sexuality, and the director's corrosive criticism of bourgeois society and the Catholic church. We will focus on historical contexts and relevant film criticism. About This Course on OpenCourseWare The instructor of this course, Elizabeth Garrels, is a Professor Emeritus at MIT. She retired in 2014 after 35 years at the Institute. Professor Garrels taught this course for over 15 years, and it evolved over this time period. Normally, a course on OCW represents the version of a course taught during a specific semester and year. However, for this course we hope to represent the evolution of the course during the main years it was taught. The materials you see here are not from a particular iteration of the course, but are drawn from all of the years the course was taught.
North American ecosystems have fundamentally changed over the late Pleistocene and Holocene; …
North American ecosystems have fundamentally changed over the late Pleistocene and Holocene; from a system dominated by mammoths, to bison, to domestic livestock. Given the very different body size and herd formation of these 'ecosystem engineers', it is likely that animals influence soil structure, water tables, vegetation and other animals in the ecosystems. What has been the ecological influence of the continued 'downsizing' of the largest animals in the ecosystem?
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This course meets weekly to discuss recent aerospace history and current events, …
This course meets weekly to discuss recent aerospace history and current events, in order to understand how they are responsible for the state of the aerospace industry. With invited subject matter experts participating in nearly every session, students have an opportunity to hone their insight through truly informed discussion. The aim of the course is to prepare junior and senior level students for their first industry experiences.
Noted Harvard scholar Henry Louis Gates, Jr. recounts the full trajectory of …
Noted Harvard scholar Henry Louis Gates, Jr. recounts the full trajectory of African-American history in his groundbreaking series The African Americans: Many Rivers to Cross. The series explores the evolution of the African-American people, as well as the multiplicity of cultural institutions, political strategies, and religious and social perspectives they developed — forging their own history, culture and society against unimaginable odds.
Using video clips from The African Americans: Many Rivers to Cross, this collection of lesson plans addresses a wide range of themes of the African-American experience from 1500 to the present.
In this module, students prepare and run an agarose gel that they …
In this module, students prepare and run an agarose gel that they use to separate DNA molecules of various sizes. Students stain the gels with ethidium bromide to visualize the positions of DNA molecules. Students estimate the sizes of separated DNA molecules by their migration distances relative to those of molecular weight standards. This module is part of a semester-long introductory lab class, Investigations in Molecular Cell Biology, at Boston College.
During World War Two, a fierce battle between American and Japanese forces …
During World War Two, a fierce battle between American and Japanese forces on Kwajalein atoll left a trail of debris on the deep lagoon floor. This lagoon now has one of the largest collections of well-preserved aircraft in the world. In this video, as part of the first ever film crew allowed onto this secret military base, Jonathan explores a B-25, F4-U Corsair and Dauntless dive bomber still sitting on the bottom of the ocean, as if ready to take off. Please see the accompanying study guide for educational objectives and discussion points.
This course is offered to undergraduates and addresses several algorithmic challenges in …
This course is offered to undergraduates and addresses several algorithmic challenges in computational biology. The principles of algorithmic design for biological datasets are studied and existing algorithms analyzed for application to real datasets. Topics covered include: biological sequence analysis, gene identification, regulatory motif discovery, genome assembly, genome duplication and rearrangements, evolutionary theory, clustering algorithms, and scale-free networks.
"Normally, an animal gets half its DNA from its mother and half …
"Normally, an animal gets half its DNA from its mother and half from its father. But Dolly had three mothers: one mother gave Dolly her DNA; one supplied an egg; and the third, her surrogate mother, gave birth to her. Dolly is an identical twin of the mother who gave her her DNA. But Dolly is six years younger."This kid-friendly Web page helps kids understand how and why Dolly was cloned, and understand the potential benefits of cloning as well as the controversy it raises.
These images from the Smithsonian Institution depict Nancy Knowlton's work with snapping …
These images from the Smithsonian Institution depict Nancy Knowlton's work with snapping shrimp in Panama. Knowlton found that the closing of the isthmus -- dividing the Pacific Ocean from the Caribbean -- resulted in new species of shrimp.
This video segment from the Secret of Life School Video: "Genetic Medicine: …
This video segment from the Secret of Life School Video: "Genetic Medicine: Tinkering with Our Genes" explores the potential for gene therapy to cure diseases like Alzheimer's.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Glioma is the most common and lethal form of brain cancer. Among patients with the highest grade of glioma, fewer than 6% survive up to 5 years after diagnosis. Interestingly, glioma is extremely rare in one large population of patients patients with Alzheimer’s disease. That suggests that an anti-glioma molecule could play a critical role in the development of Alzheimer’s. In a recent study, researchers assessed one possible candidate: presenilin-1. Presenilin-1 is a protein that assists the formation of amyloid beta, the main component of the hallmark plaques found in the brains of patients with Alzheimer’s. Experiments showed that high presenilin-1 levels in glioma tissue from patients correlated with low tumor proliferation. Closer examination revealed that presenilin-1 kept cancer from spreading by preventing tumor cells from replicating their DNA. This mechanism could explain the poor prognosis of glioma patients with low levels of presenilin-1..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"There may be a silver lining for those at high risk for Alzheimer’s: as the chance of getting the disease goes up, certain treatments may become more effective. The risk of developing Alzheimer’s largely relies on a gene called APOE, with different variants conferring more or less risk. Usually, having a high-risk allele is bad news, but a group of researchers from New York University has reported that carrying the high-risk allele could actually boost responsiveness to immunotherapy, a promising new treatment option. The APOE gene helps determine how much beta-amyloid accumulates in the brain. Beta-amyloid starts as small misfolded bits of protein that clump together to form the plaques that are the hallmark of Alzheimer’s. As the plaques appear, the brain deteriorates, particularly in regions associated with memory. One way to potentially halt this process is to use antibodies that recognize beta-amyloid. The antibodies bind to the protein and signal to the immune system to clear it out..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This annotated slideshow adapted from KET's Electronic Field Trip to the Forest …
This annotated slideshow adapted from KET's Electronic Field Trip to the Forest illustrates how blight decimated the American chestnut tree and the methods scientists use to identify and pollinate the remaining trees to create blight-resistant trees.
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