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  • experimental-design
Jell-O: More Than Meets the Eye
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CC BY-NC
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Students are tasked with designing their own experiment to discover why you cannot add fresh pineapple to Jell-O. After analyzing their results, they will construct a CER that will be used to assess their understanding of the concepts.

Subject:
Biology
Life Science
Material Type:
Activity/Lab
Assessment
Date Added:
04/26/2021
Jell-O: More Than Meets the Eye
Conditional Remix & Share Permitted
CC BY-NC
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Students are tasked with designing their own experiment to discover why you cannot add fresh pineapple to Jell-O. After analyzing their results, they will construct a CER that will be used to assess their understanding of the concepts.

Subject:
Biology
Life Science
Material Type:
Activity/Lab
Assessment
Date Added:
04/30/2019
Language Disorders in Children
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CC BY-NC-SA
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This seminar focuses on reading and discussion of current linguistic theory, first language acquisition and language disorders in young children. It also focuses on development of a principled understanding of language disorders at the phonological, morphological and syntactic levels, examining ways in which these disorders confront theories of language and acquisition.

Subject:
Arts and Humanities
Languages
Linguistics
Social Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Flynn, Suzanne
Date Added:
02/01/2013
Modeling Hot and Cold Planets: Activity A Modeling Hot and Cold Planets
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In this activity, student teams design small-scale physical models of hot and cold planets, (Venus and Mars), and learn that small scale models allow researchers to determine how much larger systems function. There is both a team challenge and competition built into this activity. Experimental findings are then used to support a discussion of human outposts on Mars. The resource includes an experimental design guide for students as well as a handout outlining a method for the design of controlled experiments, and student data sheets. Student questions and an essay assignment are provided as classroom assessments. This is Activity A in the second module, titled "Modeling hot and cold planets," of the resource, "Earth Climate Course: What Determines a Planet's Climate?" The course aims to help students to develop an understanding of our environment as a system of human and natural processes that result in changes that occur over various space and time scales.

Subject:
Atmospheric Science
Geoscience
History
History, Law, Politics
Life Science
Mathematics
Physical Science
Space Science
Material Type:
Data Set
Lesson Plan
Unit of Study
Provider:
NASA
Provider Set:
NASA Wavelength
Date Added:
11/05/2014
Nitrogen Fixation and Legume Growth
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CC BY-NC
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This is a Guided Inquiry Microbiology lab where students can use different plants and bacteria to study mutualism. They observe different growth rates of plants and some root nodules on the roots, thereby demonstrating that the mutualistic relationship between bacteria and legumes benefits growth.

Subject:
Applied Science
Environmental Science
Material Type:
Activity/Lab
Date Added:
03/06/2019
Open science challenges, benefits and tips in early career and beyond
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CC BY
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The movement towards open science is a consequence of seemingly pervasive failures to replicate previous research. This transition comes with great benefits but also significant challenges that are likely to affect those who carry out the research, usually early career researchers (ECRs). Here, we describe key benefits, including reputational gains, increased chances of publication, and a broader increase in the reliability of research. The increased chances of publication are supported by exploratory analyses indicating null findings are substantially more likely to be published via open registered reports in comparison to more conventional methods. These benefits are balanced by challenges that we have encountered and that involve increased costs in terms of flexibility, time, and issues with the current incentive structure, all of which seem to affect ECRs acutely. Although there are major obstacles to the early adoption of open science, overall open science practices should benefit both the ECR and improve the quality of research. We review 3 benefits and 3 challenges and provide suggestions from the perspective of ECRs for moving towards open science practices, which we believe scientists and institutions at all levels would do well to consider.

Subject:
Biology
Life Science
Material Type:
Reading
Provider:
PLOS Biology
Author:
Christopher Allen
David M. A. Mehler
Date Added:
08/07/2020
Population Growth in Yeasts
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Educational Use
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This lesson is the second of two that explore cellular respiration and population growth in yeasts. In the first lesson, students set up a simple way to indirectly observe and quantify the amount of respiration occurring in yeast-molasses cultures. Based on questions that arose during the first lesson and its associated activity, in this lesson students work in small groups to design experiments that will determine how environmental factors affect yeast population growth.

Subject:
Applied Science
Biology
Engineering
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
09/18/2014
Projects in Microscale Engineering for the Life Sciences
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CC BY-NC-SA
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This course is a project-based introduction to manipulating and characterizing cells and biological molecules using microfabricated tools. It is designed for first year undergraduate students. In the first half of the term, students perform laboratory exercises designed to introduce (1) the design, manufacture, and use of microfluidic channels, (2) techniques for sorting and manipulating cells and biomolecules, and (3) making quantitative measurements using optical detection and fluorescent labeling. In the second half of the term, students work in small groups to design and test a microfluidic device to solve a real-world problem of their choosing. Includes exercises in written and oral communication and team building.

Subject:
Applied Science
Biology
Engineering
Life Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Aranyosi, Alexander
Freeman, Dennis
Gray, Martha
Date Added:
02/01/2007
Research Methods in Social Psychology
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CC BY-NC-SA
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Social psychologists are interested in the ways that other people affect thought, emotion, and behavior. To explore these concepts requires special research methods. Following a brief overview of traditional research designs, this module introduces how complex experimental designs, field experiments, naturalistic observation, experience sampling techniques, survey research, subtle and nonconscious techniques such as priming, and archival research and the use of big data may each be adapted to address social psychological questions. This module also discusses the importance of obtaining a representative sample along with some ethical considerations that social psychologists face.

Subject:
Psychology
Social Science
Material Type:
Module
Provider:
Diener Education Fund
Provider Set:
Noba
Author:
Rajiv Jhangiani
Date Added:
12/22/2017
Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
Unrestricted Use
CC BY
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The reliability of experimental findings depends on the rigour of experimental design. Here we show limited reporting of measures to reduce the risk of bias in a random sample of life sciences publications, significantly lower reporting of randomisation in work published in journals of high impact, and very limited reporting of measures to reduce the risk of bias in publications from leading United Kingdom institutions. Ascertainment of differences between institutions might serve both as a measure of research quality and as a tool for institutional efforts to improve research quality.

Subject:
Biology
Life Science
Material Type:
Reading
Provider:
PLOS Biology
Author:
Aaron Lawson McLean
Aikaterini Kyriakopoulou
Andrew Thomson
Aparna Potluru
Arno de Wilde
Cristina Nunes-Fonseca
David W. Howells
Emily S. Sena
Gillian L. Currie
Hanna Vesterinen
Julija Baginskitae
Kieren Egan
Leonid Churilov
Malcolm R. Macleod
Nicki Sherratt
Rachel Hemblade
Stylianos Serghiou
Theo Hirst
Zsanett Bahor
Date Added:
08/07/2020
Sampling Arthropod Diversity of a Schoolyard
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CC BY-NC-SA
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Short Description: This is an inquiry investigation, geared toward student use of outdoor schoolyard sites. Its focus is to have students applying what they've learned about the scientific method and experimental design, gathering quantitative evidence to support hypotheses.

Subject:
Biology
Life Science
Material Type:
Activity/Lab
Assessment
Lesson Plan
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
J McClelland
Date Added:
12/09/2011
Semiconductor Manufacturing
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CC BY-NC-SA
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6.780 covers statistical modeling and the control of semiconductor fabrication processes and plants. Topics covered include: design of experiments, response surface modeling, and process optimization; defect and parametric yield modeling; process/device/circuit yield optimization; monitoring, diagnosis, and feedback control of equipment and processes; and analysis and scheduling of semiconductor manufacturing operations.

Subject:
Applied Science
Career and Technical Education
Chemistry
Electronic Technology
Engineering
Mathematics
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Boning, Duane
Date Added:
02/01/2003
Students as Scientists
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Educational Use
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Through two lessons and their associated activities, students do the work of scientists by designing their own experiments to answer questions they generate. Through a simple activity involving surface tension, students learn what a hypothesis is—and isn't—and why generating a hypothesis is an important aspect of the scientific method. In the second activity, with bubble gum to capture their interest, students learn to design and conduct controlled experiments to answer their own questions about the amounts of sugar (or artificial sweetener) in bubble or chewing gum.

Subject:
Education
Material Type:
Full Course
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
10/14/2015
Two Years Later: Journals Are Not Yet Enforcing the ARRIVE Guidelines on Reporting Standards for Pre-Clinical Animal Studies
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CC BY
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A study by David Baker and colleagues reveals poor quality of reporting in pre-clinical animal research and a failure of journals to implement the ARRIVE guidelines. There is growing concern that poor experimental design and lack of transparent reporting contribute to the frequent failure of pre-clinical animal studies to translate into treatments for human disease. In 2010, the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines were introduced to help improve reporting standards. They were published in PLOS Biology and endorsed by funding agencies and publishers and their journals, including PLOS, Nature research journals, and other top-tier journals. Yet our analysis of papers published in PLOS and Nature journals indicates that there has been very little improvement in reporting standards since then. This suggests that authors, referees, and editors generally are ignoring guidelines, and the editorial endorsement is yet to be effectively implemented.

Subject:
Applied Science
Health, Medicine and Nursing
Life Science
Material Type:
Reading
Provider:
PLOS Biology
Author:
Ana Sottomayor
David Baker
Katie Lidster
Sandra Amor
Date Added:
08/07/2020
Wet Pennies
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Educational Use
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Students conduct a simple test to determine how many drops of each of three liquids water, rubbing alcohol, vegetable oil can be placed on a penny before spilling over. Because of their different surface tensions, more water can be piled on top of a penny than either of the other two liquids. However, the main point of the activity is for students to come up with an explanation for their observations about the different amounts of liquids a penny can hold. To do this, they create hypotheses that explain their observations, and because middle school students are not likely to have prior knowledge of the property of surface tension, their hypotheses are not likely to include this idea. Then they are asked to come up with ways to test their hypotheses, although they do not need to actually conduct these tests as part of this activity.

Subject:
Applied Science
Engineering
Physical Science
Physics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
10/14/2015
Who Needs What?
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Educational Use
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The teacher leads a discussion in which students identify the physical needs of animals, and then speculate on the needs of plants. With guidance from the teacher, the students then help design an experiment that can take place in the classroom to test whether or not plants need light and water in order to grow. Sunflower seeds are planted in plastic cups, and once germinated, are exposed to different conditions. In particular, within the classroom setting it is easy to test for the effects of light versus darkness, and watered versus non-watered conditions. During exposure of the plants to these different conditions, students measure growth of the seedlings every few days using non-standard measurement. After a few weeks, they compare the growth of plants exposed to the different conditions, and make pictorial bar graphs that demonstrate these comparisons.

Subject:
Applied Science
Botany
Engineering
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
09/18/2014
Willingness to Share Research Data Is Related to the Strength of the Evidence and the Quality of Reporting of Statistical Results
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CC BY
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Background The widespread reluctance to share published research data is often hypothesized to be due to the authors' fear that reanalysis may expose errors in their work or may produce conclusions that contradict their own. However, these hypotheses have not previously been studied systematically. Methods and Findings We related the reluctance to share research data for reanalysis to 1148 statistically significant results reported in 49 papers published in two major psychology journals. We found the reluctance to share data to be associated with weaker evidence (against the null hypothesis of no effect) and a higher prevalence of apparent errors in the reporting of statistical results. The unwillingness to share data was particularly clear when reporting errors had a bearing on statistical significance. Conclusions Our findings on the basis of psychological papers suggest that statistical results are particularly hard to verify when reanalysis is more likely to lead to contrasting conclusions. This highlights the importance of establishing mandatory data archiving policies.

Subject:
Psychology
Social Science
Material Type:
Reading
Provider:
PLOS ONE
Author:
Dylan Molenaar
Jelte M. Wicherts
Marjan Bakker
Date Added:
08/07/2020
A new laboratory activity to help students learn about allelopathy and experimental design
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A new report in the journal Biochemistry and Molecular Biology Education describes a laboratory activity meant to help students understand allelopathy – a type of chemical warfare used by plants to secure the resources needed to grow. In this process, plants release biochemicals that affect the growth or development of neighboring plants. It is a common tactic of invasive plant species. The mechanism has also been used in agricultural production systems as a sustainable and organic way to manage weeds and soil fertility. For example, horseradish produces the molecule sinigrin, which is hydrolyzed in the presence of the enzyme myrosinase to generate allyl isothiocyanate, or AITC. AITC has been shown to have allelopathic effects on lettuce, including reduced and delayed seed germination rates, decreased root hair growth, and decreased root length. Mustard green also contains AITC and is widely utilized to control weed growth in current agriculture production..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Biology
Chemistry
Health, Medicine and Nursing
Life Science
Physical Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019