The uses of animals in biotechnology are expansive, and many times overlooked.  This lesson will have students exploring the wide range of uses of animals in biotechnology and formulating an opinion about the uses of animals in biotechnology.

Bioremediation is a useful biotechnology application that can help maintain and preserve our natural resources from harmful substances.  However, bioremediation can be complicated and present numerous challenges, as well.  Many times, we are unaware of environmental contamination present in our local areas.  Through this lesson, students will explore the basics of bioremediation and then participate in a local case study.

Everyday, we are surrounded by, and use, numerous products that are the result of biotechnology. However, some of these products face more criticism and controversy than others.  Through this lesson, students will be presented with two scenarios regarding biotechnology products, and they must complete research and formulate opinions regarding these topics.  The class will participate in a class discussion related to the biotechnology products and topics. 

If the dialysis is the most know method used for buffer exchange, other methods less as desalting and tangential flow filtrations can be useful to speed up or scale up the buffer exchange process.

This course has been designed as a seminar to give students an understanding of how scientists with medical or scientific degrees conduct research in both hospital and academic settings. There will be interactive discussions with research clinicians and scientists about the career opportunities and research challenges in the biomedical field, which an MIT student might prepare for by obtaining an MD, PhD, or combined degrees. The seminar will be held in a case presentation format, with topics chosen from the radiological sciences, including current research in magnetic resonance imaging, positron emission tomography and other nuclear imaging techniques, and advances in radiation therapy. With the lectures as background, we will also examine alternative and related options such as biomedical engineering, medical physics, and medical engineering. We'll use as examples and points of comparisons the curriculum paths available through MIT's Department of Nuclear Science and Engineering. In past years we have given very modest assignments such as readings in advance of or after a seminar, and a short term project.

Many biotechnology applications rely on the DNA replication process.  Through this lesson, students will better understand the DNA replication process and connect it to other biotechnology processes.

Gene mutations occur naturally through the DNA replication process with some results being fatal and others being helpful.  This lesson will explore the types of mutations that occur, the effect they have on DNA, and examples of diseases or conditions caused by the specific type of mutation.  Students will participate in a gallery walk to learn more about the types of mutations. 

Many times, gene mutations lead to some sort of genetic disease or disorder.  Through this lesson, students will explore a genetic disease, caused by a specific type of gene mutation (previously learned about) and present their findings to the class.   

Through six lesson/activity sets, students learn about the functioning of sensors, both human and robotic. In the activities, student groups use LEGO MINDSTORMS(TM) NXT robots and components to study human senses (sight, hearing, smell, taste, touch) in more detail than in previous units in the series. They also learn about the human made rotation, touch, sound, light and ultrasonic sensors. "Stimulus-sensor-coordinator-effector-response" pathways are used to describe the processes as well as similarities between human/animal and robotic equivalent sensory systems. The important concept of sensors converting/transducing signals is emphasized. Through assorted engineering design challenges, students program the LEGO robots to respond to input from various LEGO sensors. The overall framework reinforces the theme of the human body as a system with sensors that is, from an engineering perspective. PowerPoint® presentations, quizzes and worksheets are provided throughout the unit.

This class is a project-based introduction to the engineering of synthetic biological systems. Throughout the term, students develop projects that are responsive to real-world problems of their choosing, and whose solutions depend on biological technologies. Lectures, discussions, and studio exercises will introduce (1) components and control of prokaryotic and eukaryotic behavior, (2) DNA synthesis, standards, and abstraction in biological engineering, and (3) issues of human practice, including biological safety; security; ownership, sharing, and innovation; and ethics. Enrollment preference is given to freshmen.
This subject was originally developed and first taught in Spring 2008 by Drew Endy and Natalie Kuldell. Many of Drew's materials are used in this Spring 2009 version, and are included with his permission.
This OCW Web site is based on the OpenWetWare class Wiki, found at OpenWetWare: 20.020 (S09)

This course, intended for both graduate and upper level undergraduate students, will focus on understanding of the basic molecular structural principles of biological materials. It will address the molecular structures of various materials of biological origin, such as several types of collagen, silk, spider silk, wool, hair, bones, shells, protein adhesives, GFP, and self-assembling peptides. It will also address molecular design of new biological materials applying the molecular structural principles. The long-term goal of this course is to teach molecular design of new biological materials for a broad range of applications. A brief history of biological materials and its future perspective as well as its impact to the society will also be discussed. Several experts will be invited to give guest lectures.

I ProteoCool is a an open source with simple but Cool Protocols for newbies in the field of molecular biology and protein chemistry.

Check the video to see how you can stain and destain your SDS-page in few minutes thanks to the use of a microwave owen.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Fixing carbon through biological methanation is a promising technology for generating renewable energy. It remains unclear, however, how microbial species interact to generate biogas. To find out, researchers explored the community dynamics of microbes found in biofilms from four biogas reactors. Metagenomics revealed 59 species of microbes with five accounting for more than 70% of total abundance in the four reactors under investigation. Experiments showed that Firmicutes spp. GSMM966 and GSMM974 and Limnochordia sp. GSMM975 played a central role in biofilm formation. And metabolic reconstruction indicated complex metabolisms for the two dominant species M. wolfeii GSMM957 and Limnochordia sp. GSMM975. Simulations of the core biofilm community showed that these same species exhibit the highest increases in growth rate with increasing uptake. And cross-feeding interactions, not easily measured in vivo, were visualized..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This website was created by the GMO working group in the UConn College of Agriculture, Health and Natural Resources. We offer clear descriptions and explanations of a variety of issues related to genetically modified organisms, or GMOs. We hope you find the information useful, and we welcome your feedback. We thank Purdue Agriculture for inspiration, the format and assistance in building this site.