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American Red Cross First Aid-CPR-AED Resources
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CC BY-NC-ND
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American Red Cross First Aid-CPR-AED Resources:Responding to Emergencies: Comprehensive First Aid, CPR, and AED. American Red Cross is the Author and publisher of these resource materials.

Subject:
Health, Medicine and Nursing
Material Type:
Activity/Lab
Assessment
Diagram/Illustration
Interactive
Lecture
Lecture Notes
Lesson
Lesson Plan
Primary Source
Reading
Simulation
Student Guide
Textbook
Author:
Shirley Stewart
Date Added:
01/12/2022
Anatomy of high-impact publications in orthopedics
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Citation rates and journal impact factor are the most widely used measures of influence in the academic world. But true impact extends well beyond the sphere of research. While quantifying this influence has remained incredibly challenging, social media and the alternative metrics its supplies are beginning to change that. In a new study reported in The American Journal of Sports Medicine, researchers looked at how these “altmetrics” correlate with traditional measures of impact in the field of orthopedics. Their findings point to the types of studies and publication venues that attain the greatest reach. The authors of the study analyzed 496 articles published across five high-impact journals in 2016: The Journal of Bone and Joint Surgery; Clinical Orthopaedics and Related Research; Acta Orthopaedica; Knee Surgery, Sports Traumatology, Arthroscopy; and The American Journal of Sports Medicine..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/25/2020
Anatomía y fisiología cardiaca
Conditional Remix & Share Permitted
CC BY-NC
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Esta es una lección virtual sobre los conceptos básicos de cardiología, que permitirán identificar las estructuras del sistema cardiaco, su fisiología y el sistema eléctrico del corazón, lo cual es fundamental para poder comprender temas de mayor complejidad a nivel cardiaco.

Subject:
Health, Medicine and Nursing
Material Type:
Lesson
Author:
Almy Merida
Date Added:
09/04/2021
Anesthetic protects rat brains from damage after stroke
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Scientists have long thought that anesthetic drugs might protect the brain during a stroke, but there was no way to rigorously test this idea because triggering strokes in animals requires the use of anesthesia. But now, a team of neuroengineers in China has come up with a work-around. Using lasers and a photosensitive dye, researchers set off strokes without needing to put animals to sleep, allowing them to finally disentangle the role of anesthetics on these often devastating events. The team first installed cranial windows in 22 rats to provide access to a critical artery in the brain. A day later, the neuroscientists injected the rats with a photosensitive dye. Then, by shining a laser on that artery, they could activate the dye to begin clotting, prompting an ischemic stroke -- without having to anesthetize first. Using this method, the researchers triggered strokes in two groups of rats. Half received the anesthetic isoflurane and were asleep, while the other half did not, and were awake..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/16/2022
Another mechanism for the initiation and progression of Parkinson’s disease?
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A recent study published in Acta Neuropathologica Communications has found a potential mechanism for the initiation and development of Parkinson’s disease and it appears red blood cells may be partly to blame. Parkinson’s is a chronic and progressive neurodegenerative disorder commonly associated with tremors, muscle stiffness, and impaired movement. While these symptoms are caused by the deterioration of nerve cells in the brain, the precise cause of the disease is still not fully understood. What is known is that the development of Parkinson’s is associated with the aggregation of toxic forms of a protein named alpha-synuclein (or alpha-syn, for short) in the brain. Recent evidence, however, suggests alpha-syn found in the blood can also be problematic and this has been implicated as a contributor to brain-cell breakdown..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Anterolateral structure (ALS) injury is significant risk factor for grade 3 pivot shift in knees with acute ACL injuries
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Among patients undergoing ACL reconstruction surgery, a high-grade pivot shift before surgery is widely considered to confer an increased risk of graft rupture and persistent instability after surgery. But what are the risk factors for high-grade pivot shifts themselves? A new study published in The American Journal of Sports Medicine reports injury to anterolateral structures as the most important risk factor for high-grade pivot shifts in patients suffering ACL injuries. The pivot shift test is the most specific physical exam for diagnosing ACL injuries. The examiner applies inward pressure on the lateral thigh with one hand while internally rotating the lower leg as the knee is flexed from a fully extended position. The presence of a pivot shift is indicated by an abrupt forward shift of the tibia back to its normal anatomical position. This shift is graded between 1 and 3 according International Knee Documentation Committee criteria, with 1 and 2 considered low grade, and 3 considered high grade..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/23/2020
Antiplatelet drugs might help, not harm, survivors of brain haemorrhage
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"More than one-third of people who’ve survived brain hemorrhage stop taking oral anti-blood-clotting drugs, like aspirin. Normally taken to prevent blood vessel blockage, so-called antiplatelet drugs increase the risk of bleeding in general. So they’re widely believed to increase the risk of brain hemorrhage happening again. But new research suggests that might not be the case. Researchers came to that conclusion following a randomized trial involving more than 500 survivors of brain hemorrhage in the UK. Participants were mostly men over the age of 70; all had a history of diseases that cause blockage of blood flow due to clotting but had stopped taking oral antiplatelet drugs after their brain hemorrhage. Researchers split those patients into two groups: half were encouraged to start antiplatelet drugs, and half were encouraged to stay off these drugs..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/23/2019
Análisis de poder estadístico y cálculo de tamaño de muestra en R: Guía práctica
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CC BY
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Esta guía práctica acompaña la serie de videos Poder estadístico y tamaño de muestra en R, de mi canal de YouTube Investigación Abierta, que recomiendo ver antes de leer este documento. Contiene una explicación general del análisis de poder estadístico y cálculo de tamaño de muestra, centrándose en el procedimiento para realizar análisis de poder y tamaños de muestra en jamovi y particularmente en R, usando los paquetes pwr (para diseños sencillos) y Superpower (para diseños factoriales más complejos). La sección dedicada a pwr está ampliamente basada en este video de Daniel S. Quintana (2019).

Subject:
Applied Science
Biology
Health, Medicine and Nursing
Life Science
Mathematics
Psychology
Social Science
Statistics and Probability
Material Type:
Reading
Author:
Juan David Leongómez
Date Added:
08/18/2020
Applying network science to better understand anesthetic drugs
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"For an anesthesiologist, medically induced transitions between conscious and unconscious brain states are just part of the daily routine. But precisely how general anesthetics produce a state of unconsciousness isn’t all that clear. That’s because researchers are missing a key piece to the puzzle: no one has been able to definitively pinpoint exactly where consciousness comes from. The prevailing idea is that there’s no single “seat” of consciousness – it’s more the product of multiple interactions occurring throughout the brain. A recent review article published in the journal Anesthesiology argues that, because of this global network property, the field of network science could provide the framework needed to more comprehensively understand the biological basis of consciousness…and by extension the principles underlying anesthetic-induced unconsciousness..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Aqueous humour outflow imaging: seeing is believing
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Over the past decade, a variety of new drugs and surgical techniques have been developed to lower intraocular pressure and treat glaucoma. This trend has reinvigorated interest in understanding how and where aqueous humour outflow occurs. Three main pathways are currently known: trabecular, or **_conventional_**, outflow; uveoscleral, or **_unconventional_**, outflow; and subconjunctival outflow. Current methods for imaging these pathways are at varying stages of development, with conventional outflow imaging being the most advanced. Nevertheless, each route possesses a unique biology that can be leveraged in the quest for more knowledge about aqueous humour outflow. Conventional outflow accounts for approximately 90% of aqueous humour flow under physiologic conditions. Here, imaging methods have focused on capturing structural or flow-based features. Optical coherence tomography has enabled researchers to assess ocular tissue in live human subjects..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
02/26/2021
Artificial enzymes facilitate targeted cancer therapy
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Despite their known benefits, chemotherapy and other cancer treatments can take a toll on patients. Side effects such as hair loss, nausea, immune system suppression, fatigue, cognitive impairment, and infertility are common. The reason is that many cancer-fighting treatments target cells that quickly reproduce, which is true of cancer cells but also of other, healthy cells in the body, including blood cells and those lining the gastrointestinal tract. Is it possible to target only cancerous tissues with therapeutic drugs so that healthy organs remain unaffected? Researchers at the RIKEN Cluster for Pioneering Research in Japan are engineering molecules to do just that. The team showed that artificially designed gold-based enzymes (or metalloenzymes) can be used to guide drug delivery through a technique called selective cell tagging therapy. These metalloenzymes are studded with sugar molecules that can bind to specific proteins called lectins displayed on the surface of cancer cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/12/2021
Assessing the ‘sterile womb’ and ‘in utero colonization’ hypotheses
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Research is increasingly showing the impact of the microbiome -- the diverse microbial communities living within the gut -- on human health. But, _when_ and _how_ is the microbiome established? Two opposing hypotheses have been put forward. For over a century, the prevailing thought has been that the human fetal environment is sterile and that microbes are acquired during and after birth. If this view is correct, the microbiome of infants born via C-section should differ from those born vaginally. Recent studies using molecular techniques, however, suggest that bacterial communities may be present in the placenta, amniotic fluid, and the baby’s first stool. They posit that the acquisition of the gut microbiome, therefore, begins _in utero_. If this is the case, delivery method should have less of an effect on early microbiome assembly..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/20/2020
Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Consuming high amounts of red meat is commonly linked to an increased risk of developing cancer, especially colorectal cancer. At the same time, antibodies against Neu5Gc , a carbohydrate derived from red meat, have been observed to worsen cancer in “human-like” mice. While these antibodies and red meat consumption are each believed to increase cancer risk, it remains unknown how diet affects the antibodies. Now, research suggests that consuming Neu5Gc from red meat and dairy can modulate the amounts and properties of anti-Neu5Gc antibodies in humans, providing clues to how the carbohydrate might be linked to cancer. The team behind the study calculated daily intake of Neu5Gc for more than 19,000 subjects aged 18 years or older. These participants provided regular logs of food consumed over 24-hour periods as part of the NutriNet-Santé study, which was designed to investigate relationships between nutrition and health status..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Life Science
Nutrition
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
02/26/2021
Auditory icon alarms easier to identify than standard melodic alarms in a simulated intensive care setting
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Accurate identification of medical alarm sounds can be life-saving, but current standard alarms are difficult to learn. One issue is that these alarms, despite having different melodies, possess highly similar tonal qualities. This makes it hard to distinguish, for example, an alarm indicating an abnormal heart rate from one denoting abnormal oxygen saturation. To ease interpretation, researchers have developed new auditory icon alarms. These real-world sounds are associated with the processes they represent, such as the sound made by pills rattling in a bottle to indicate a drug administration issue or the sound of assisted breathing to denote abnormal ventilation parameters. The intuitive reaction to such sounds should make the icon alarms easier to identify than standard alarms, creating new possibilities to improve patient safety. The team tested the usability of the icons in a simulated intensive care unit..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Automated anesthetic management and cognition outcomes
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Many older patients experience a kind of ‘brain fog’ following surgery, in which cognition is impaired from lingering effects of anesthesia. It’s temporary, but can still be disruptive. Now, there is early evidence that one way to prevent such problems is to automate more aspects of anesthetic management during surgery. That’s the preliminary finding from a new randomized controlled trial appearing in the journal Anesthesiology. Researchers at a hospital in Belgium tested whether automating three aspects of anesthetic management -- anesthetic depth, cardiac blood flow, and protective lung ventilation -- improved performance on cognitive tests post-op, compared to when an anesthesiologist is in manual control. Going in, the idea was that machines could do an even better job than humans at keeping parameters within the recommended ranges, and this might lead patients to have less post-op cognitive impairment..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/23/2020