The course includes survey and special topics designed for graduate students in the brain and cognitive sciences. It emphasizes ethological studies of natural behavior patterns and their analysis in laboratory work, with contributions from field biology (mammology, primatology), sociobiology, and comparative psychology. It stresses mammalian behavior but also includes major contributions from studies of other vertebrates and of invertebrates. It covers some applications of animal-behavior knowledge to neuropsychology and behavioral pharmacology.

This experiment demonstrates the effect of muscarinic agonists and its parasympathetic effects such as lacrimation (shedding of red tears), salivation, defaecation, urination pilo-erection, rhinorrhea, sweating and labored breathing.This module has been internally reviewed by a cross-disciplinary committee within KNUST prior to releasing as an Open Educational Resource.

Bulletin of Environment, Pharmacology and Life Sciences [BEPLS] is a monthly peer reviewed open access international journal focused towards the rapid publication of fundamental research papers on all areas of Environment, Pharmacology and Life Sciences. BEPLS is official publication of Academy for Environment and Life Sciences [Regd. Under Societies Registration Act XXI, 1860]

The focus and the scope of journal include:
Biochemistry
Biotechnology
Endocrinology
Molecular Biology
Cellular Biology
Environmental Biology
Environmental Chemistry
Pharmacology
Economic Zoology and Botany
Embryology
Nanotechnology
Microbiology
Agricultural Sciences
Ecology
Medical Sciences
Toxicology, etc.

Resources for Canadian Medical Trainees

Long Description:
The first comprehensive open textbook on Clinical Pharmacology, Toxicology and Prescribing Competence for medical students across Canada. There is well documented evidence that knowledge and appropriate prescribing of medication reduces patient mortality and disability, and improves the cost-effectiveness and sustainability of the healthcare system. There is a large learning gap amongst medical students, strong interest in a national resource amongst medical school faculty, and the lack of any national online resource. This open textbook provides access to these resources in a coherent, organized manner.

Word Count: 5567

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Successful Pharmacology course completion requires students to mentally overlay complex mechanisms of drug action onto intricate body physiology to make sense of how drugs both correct and cause disease. Unfortunately, many students (undergraduate – health professional) lack the needed study/critical thinking skills required to navigate this complex curriculum. Providing students with lecture content and study guides is only a partial solution as they often fail, alone, to adequately convey the thought structure required for student success. Therefore, this series of application/critical thinking worksheets was developed to demystify, model, and guide students through the critical thinking processes that need to be employed when engaging the Pharmacology curriculum.

Scientists who are working to discover new medicines often use robots to prepare samples of cells, allowing them to test chemicals to identify those that might be used to treat diseases. Students will meet a scientist who works to identify new medicines. She created free software that ''looks'' at images of cells and determines which images show cells that have responded to the potential medicines. Students will learn about how this technology is currently enabling research to identify new antibiotics to treat tuberculosis. Students will complete hands-on activities that demonstrate how new medicines can be discovered using robots and computer software, starring the student as ''the computer.'' In the process, the students learn about experimental design, including positive and negative controls.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The physiological effects of melatonin are far reaching, from acting as an neuroprotective agent to regulating circadian rhythms and sleep cycles. An imbalance of this hormone has even been linked to neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s. The precise molecular mechanism by which melatonin exerts these effects, however, remains a mystery. To shed light on this process, a team of researchers has developed a melatonin-like compound that is unable to penetrate the cell membrane and binds only to cell-surface receptors. Melatonin’s physiological effects on the brain are controlled by the lock-and-key-like properties of this hormone and its receptors. When melatonin binds to its corresponding receptor, a biochemical signal is sent into the cell. But recent data suggests that this interaction may also occur inside the cell, itself. Specifically, on mitochondria within brain cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This class is a multidisciplinary introduction to pharmacology, neurotransmitters, drug mechanisms, and brain diseases from addiction to schizophrenia.
From Abilify® to Zyrtec®, the world is full of fascinating drugs. If you are poisoned by sarin nerve gas, you may be able to save your life by huffing some BZ nerve gas. This class will explain that chemical curiosity, along with a host of other interesting tidbits of pharmacology. The structure of the class interleaves basic concepts with specific examples and entertaining tangents, so it is not loaded with boring abstract theory. In the first class you will learn what a neurotransmitter is, and you will immediately apply that knowledge when we discuss the mechanism of caffeine. The class is highly multidisciplinary, including topics such as patent law, medical ethics, history, and the physics of crack pipes.

This class is a multidisciplinary introduction to pharmacology, neurotransmitters, drug mechanisms, and brain diseases from addiction to schizophrenia.

The target learner will have started in a dental hygiene program and have basic knowledge of common medical emergencies that may occur in the dental office. As a dental hygiene student, this lesson will enhance the learner's knowledge on basic emergency drug use as a dental hygienist in a clinic. Ideally, the learner would have completed the lesson regarding emergency drugs in their pharmacology course and can utilize this lesson as a supplement to self refelect on their retention of knowledge and key take aways.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"NTRK, ROS1, and ALK gene fusions are recognised oncodrivers in many cancers. Oncogenic fusions result in constitutively active tyrosine kinases and downstream activation of pathways associated with tumour growth, survival, and proliferation. NTRK fusions, for example, are found in both adult and paediatric cancers and are extremely common in some rare cancers. All three fusion types are found in non–small cell lung cancer. At diagnosis, many patients with NTRK-fusion-positive solid tumours, including NTRK-positive non–small cell lung cancer, or with ROS1-positive non–small cell lung cancer also have brain metastases. These metastases are linked to a worse prognosis. Although effective drugs exist for both NTRK-positive solid tumours and ROS1-positive non–small cell lung cancer, most don’t penetrate the CNS well enough to treat brain metastases. Entrectinib, an orally active small-molecule tyrosine kinase inhibitor that selectively inhibits TRK, ROS1 and ALK, acts in both the periphery and the CNS..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

An isolated frog heart preparation is useful in the study of cardiac cell excitation. The small size of the frog's heart means that drugs applied to the outside of the heart will peneterate the myocardium and modify the functions of the heart's cardiac chambers. Thus, the effect of the autonomic neurotransmitter substance together with their modification by other drugs can be studied by addition of these agents to the heart.This module has been internally reviewed by a cross-disciplinary committee within KNUST prior to releasing as an Open Educational Resource.

A Conceptual Approach

Short Description:
This adapted open-access Canadian Nursing Pharmacology textbook was designed specifically for the entry-level undergraduate nursing student. It is also applicable to other health disciplines for use. This textbook explores pharmacological concepts by showing the connections between pathophysiology, pharmacological principles, and common medication classes. This textbook also provides learning tools to improve the students retention with quizzes, videos, concept maps, drug cards, and is organized using a concept-based teaching approach.

Word Count: 148970

ISBN: 978-1-77420-211-1

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

This module contains a series of demonstration videos on how to do isolated smooth muscle preparation in vitro using the Harvard Kymograph simulator. This series is complementary to the video Setting Up the Harvard Kymograph.This module has been internally reviewed by a cross-disciplinary committee within KNUST prior to releasing as an Open Educational Resource.

This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets.

Medicines By Design aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. Much of the most promising pharmacological research going on at universities across the country is sponsored by the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH), U.S. Department of Health and Human Services. Working at the crossroads of chemistry, genetics, cell biology, physiology, and engineering, pharmacologists are fighting disease in the laboratory and at the bedside.

The neuropharmacology course will discuss the drug-induced changes in functioning of the nervous system. The specific focus of this course will be to provide a description of the cellular and molecular actions of drugs on synaptic transmission. This course will also refer to specific diseases of the nervous system and their treatment in addition to giving an overview of the techniques used for the study of neuropharmacology.
This course is offered during the Independent Activities Period (IAP), which is a special 4-week term at MIT that runs from the first week of January until the end of the month.

Word Count: 143265

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Word Count: 143694

ISBN: 9781734914108

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Word Count: 161926

ISBN: 9781734914122

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)