Becoming Human is an interactive documentary experience that tells the story of human origins. Multimedia, research and scholarship are presented to promote greater understanding of the course of human evolution. This site includes classroom materials, subject-designed exercises, games and activities to help make connections between the concepts that are presented and student learning. PDF versions of the resources may be downloaded from the site.

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

LEARNING OUTCOMESDifferentiate between two kinds of chromosomes: autosomes and sex chromosomesUnderstand how DNA is protected and compacted inside cells

Your body is made of cells -- but how does a single cell know to become part of your nose, instead of your toes? The answer is in your body's instruction book: DNA. Joe Hanson compares DNA to detailed manual for building a person out of cells -- with 46 chapters (chromosomes) and hundreds of thousands of pages covering every part of you.

Instructional video on the formation of catenane after replication of circular bacterial chromosome.

Although textbooks describe this process and show illustrations, it is difficult to grasp without seeing a live demonstration.

Created for Biology 41 General Genetics at Tufts University.

In this video collaboration from Khan Academy and 23andMe, you'll find out why women don't have a Y chromosome. Even with no Y, women can still learn about their paternal ancestry with genetic testing from services like 23andMe.

Students randomly select jelly beans (or other candy) that represent genes for several human traits such as tongue-rolling ability and eye color. Then, working in pairs (preferably of mixed gender), students randomly choose new pairs of jelly beans from those corresponding to their own genotypes. The new pairs are placed on toothpicks to represent the chromosomes of the couple's offspring. Finally, students compare genotypes and phenotypes of parents and offspring for all the "couples" in the class. In particular, they look to see if there are cases where parents and offspring share the exact same genotype and/or phenotype, and consider how the results would differ if they repeated the simulation using more than four traits.

The Genetics Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Students use model chromosomes and answer analysis and discussion questions to learn about meiosis and fertilization. As they model meiosis and fertilization, students follow the alleles of a human gene from the parents' body cells through gametes to zygotes; thus, students learn how a person inherits one copy of each gene from each of his/her parents. To learn how meiosis contributes to genetic variation, students analyze the results of crossing over and independent assortment. Students also compare and contrast meiosis and mitosis, and they learn how a mistake in meiosis can result in Down syndrome or death of an embryo. This activity helps students meet the Next Generation Science Standards.

This initial module from the GENIQUEST project introduces the dragons and the inheritance of their traits, then delves into meiosis and its relationship to inherited traits. Students examine the effects of choosing different gametes on dragon offspring, and learn about genetic recombination by creating recombination events to generate specific offspring from two given parent dragons. Students learn about inbred strains and breed an inbred strain of dragons themselves.

This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics.

This course is a reading supplement to Cells: Molecules and Mechanism by E.V. Wong

In a class discussion format, the teacher presents background information about basic human genetics. The number of chromosomes in both body cells and egg and sperm cells is covered, as well as the concept of dominant and recessive alleles. Students determine whether or not they possess the dominant allele for the tongue-rolling gene as an example.