How genetics can add to our understanding of cognition, language, emotion, personality, and behavior. Use of gene mapping to estimate risk factors for psychological disorders and variation in behavioral and personality traits. Mendelian genetics, genetic mapping techniques, and statistical analysis of large populations and their application to particular studies in behavioral genetics. Topics also include environmental influence on genetic programs, evolutionary genetics, and the larger scientific, social, ethical, and philosophical implications.

This is a coloring book that I drew and designed as a fun way for my students to review information and/or doodle on. The pictures are inspired by images I use in my General Biology I class, and are presented in the same order as they are discussed in my class. The coloring book is NOT designed as an alternative to attending lecture, studying notes, etc. You can download the PDF of the coloring book and then color the pictures on an app (like using an iPad and Apple Pencil) or print out the images and color them using your preferred method (like with colored pencils).

Host Harry Kreisler Welcomes Professor Sir John Gurdon for a discussion of advances in research on cell biology. Sir John reflects on his career as a scientist including his path breaking research on cloning. He offers insights into the implications of the revolution in the biological sciences.(46 min)

Precise modification of faulty genes for repair has been one of the most important goals in medicine. It is now finally within the realm of possibility thanks to the gene editing tool CRISPR. This microbial adaptive immune system can copy and cut specific DNA sequences. This animation provides a visual introduction of this revolutionary genetic tool.

Precise modification of faulty genes for repair has been one of the most important goals in medicine. It is now finally within the realm of possibility thanks to the gene editing tool CRISPR. This microbial adaptive immune system can copy and cut specific DNA sequences. This animation provides a visual introduction of this revolutionary genetic tool.

Short Description:
This book provides an introduction to the genetic concepts of reproductive systems, recombination, mutation, segregation and linkage analysis, inbreeding, quantitative inheritance, fertility regulation, population genetics and polyploidy.

Long Description:
This book provides an introduction to the genetic concepts of reproductive systems, recombination, mutation, segregation and linkage analysis, inbreeding, quantitative inheritance, fertility regulation, population genetics and polyploidy.

Word Count: 61452

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

This course will explore the current frontiers of the world of RNA biology with primary research papers to trace how the original odd detail sometimes leads to major discoveries. As we discuss the different transcripts and processing events that enable this exciting diversity of RNA functions, we invite you to read landmark papers with us, think critically, and ask new questions, as we marvel at the wonders of RNA.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Explore the relationship between the genetic code on the DNA strand and the resulting protein and rudimentary shape it forms. Through models of transcription and translation, you will discover this relationship and the resilience to mutations built into our genetic code. Start by exploring DNA's double helix with an interactive 3D model. Highlight base pairs, look at one or both strands, and turn hydrogen bonds on or off. Next, watch an animation of transcription, which creates RNA from DNA, and translation, which 'reads' the RNA codons to create a protein.

Students learn the principles of independent assortment and gene linkage in activities which analyze inheritance of multiple genes on the same or different chromosomes in hypothetical dragons. Students learn how these principles derive from the behavior of chromosomes during meiosis and fertilization.

In this simulation activity students mimic the processes of meiosis and fertilization to investigate the inheritance of multiple genes and then use their understanding of concepts such as dominant/recessive alleles, incomplete dominance, sex-linked inheritance, and epistasis to interpret the results of the simulation. This activity can be used as a culminating activity after you have introduced classical genetics, and it can serve as formative assessment to identify any areas of confusion that require additional clarification.

During development a single totipotent cell gives rise to the vast array of cell types present in the adult human body, yet each cell has essentially the same DNA sequence. As cells differentiate, distinct sets of genes must be coordinately activated and repressed, ultimately leading to a cell-type specific pattern of gene expression and a particular cell fate. In eukaryotic organisms, DNA is packaged in a complex protein super structure known as chromatin. Modification and reorganization of chromatin play a critical role in coordinating the cell-type specific gene expression programs that are required as a cell transitions from a pluripotent stem cell to a fully differentiated cell type. Epigenetics refers to such heritable changes that occur in chromatin without altering the primary DNA sequence. This class will focus on the role of epigenetic regulation with respect to developmental fate and also consider the fact that the epigenetic mechanisms discussed have broad implications, including how seemingly normal cells can be transformed into cancerous cells.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Epigenetics - our epigenome - controls how our genes behave without altering their sequence. Just about everything affects it, from nutrition, drugs, and toxins to child rearing, culture, and society. Many diseases, from obesity to addiction to cancer, can be linked to epigenetic modifications. Furthermore, throughout development and life, from conception to death, the exposures you have will not only affect your own epigenome, but potentially also your child’s, and your grandchild’s. This rapidly expanding field of biological, physiological, sociological, and psychological research could be key to discovering why, and more importantly how, we are the way we are.

Epigenetics has consequences for medicine, pregnancy, childcare, law and how we live on an everyday basis. This book will provide a comprehensive introduction to the mechanisms and real-life consequences of epigenetics, and will arm the reader with the knowledge necessary to make informed decisions about the future of epigenetics in modern society. This is a call for serious consideration about the effects of epigenetics on society.

In this class, students engage in independent research projects to probe various aspects of the physiology of the bacterium Pseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production.
Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized.
WARNING NOTICE
The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented.
Legal Notice

This project-based laboratory course provides students with in-depth experience in experimental molecular genetics, using modern methods of molecular biology and genetics to conduct original research. The course is geared towards students (including sophomores) who have a strong interest in a future career in biomedical research. This semester will focus on chemical genetics using Caenorhabditis elegans as a model system. Students will gain experience in research rationale and methods, as well as training in the planning, execution, and communication of experimental biology.
WARNING NOTICE
The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented.
Legal Notice

Sign up for a free account on the Gizmo website (https://www.explorelearning.com/index.cfm?method=Controller.dspFreeAccount) for free access to two simulations that were collaboratively developed by the teams at Explore Learning and the Wisconsin Fast Plants Program of the University of Wisconsin-Madison. These simulations replace those previously available on our website that were developed nearly two decades ago and no longer function on modern operating systems. Fast Plants Gizmos were created as a collaboration between ExploreLearning and the Wisconsin Fast Plants Program of the University of Wisconsin-Madison. They weredesigned to support many of the experiments that students can do using Fast Plants seeds and plants. By using these Gizmos in combination with firsthand experiences growing Fast Plants, students can compare simulated growth, development and reproduction with observations of living Fast Plants. In addition, the Gizmos genetic simulation makes it possible for students to gather data from a significantly larger plant population than is typically grown in classrooms. These Gizmos also stand alone, supporting topics both in plant life cycles and Mendelian genetics and can be used by any student. Simulation, Simulations, Genetics, Inheritance

Instructional video on the formation of catenane after replication of circular bacterial chromosome.

Although textbooks describe this process and show illustrations, it is difficult to grasp without seeing a live demonstration.

Created for Biology 41 General Genetics at Tufts University.

Since the discovery of the structure of the DNA double helix in 1953 by Watson and Crick, the information on detailed molecular structures of DNA and RNA, namely, the foundation of genetic material, has expanded rapidly. This discovery is the beginning of the "Big Bang" of molecular biology and biotechnology. In this seminar, students discuss, from a historical perspective and current developments, the importance of pursuing the detailed structural basis of genetic materials.

For more than two decades J. Craig Venter and his research teams have been pioneers in genomic research. Regarded as one of the leading scientist of the 21st century, Venter discusses how he is applying tools and techniques developed to sequence the human genomes to discover new genes of microbes from around the world. (57 minutes)

This problem challenges students to design experiments using techniques measuring gene expression (reverse transcriptase PCR, microarrays, in situ hybridization).

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.