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Abl kinase’s disordered region plays roles in protein function and stability
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The non-receptor tyrosine kinase Abelson (Abl) is a key player in oncogenesis, causing diseases including chronic myelogenous and acute lymphoblastic leukemia. Drugs targeting Abl kinase activity serve as paradigms of targeted therapy. Drosophila is an ideal model for studying Abl’s function because there is only a single fly Abl family member. In flies, Abl is essential for embryonic morphogenesis, playing diverse roles in embryonic and adult viability. To examine the role of the intrinsically disordered region (IDR) of Abl, researchers deleted the IDR in Drosophila. They found that Abl lacking the IDR was not able to rescue the roles of Abl in viability and embryonic morphogenesis. The IDR was also essential for cell shape changes and cytoskeletal regulation during embryonic morphogenesis and, surprisingly, for modulating protein stability..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/16/2021
Abnormal
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CC BY-NC-SA
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Selection of reading resources for Abnormal Psychology courses.
These resources were compiled by Dr. Susan Harvey, Professor at Delta College

Subject:
Life Science
Material Type:
Reading
Date Added:
09/19/2018
Abnormal
Conditional Remix & Share Permitted
CC BY-NC-SA
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Selection of reading resources for Abnormal Psychology courses.
These resources were compiled by Dr. Susan Harvey, Professor at Delta College

Subject:
Life Science
Material Type:
Reading
Date Added:
09/19/2018
Abnormal Language
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CC BY-NC-SA
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Introduction to the linguistic study of language pathology, concentrating on experimental approaches and theoretical explanations. Discussion of Specific Language Impairment, autism, Down syndrome, Williams syndrome, normal aging, Parkinson's disease, Alzheimer's disease, hemispherectomy and aphasia. Focuses on the comparison of linguistic abilities among these syndromes, while drawing clear comparisons with first and second language acquisition. Topics include the lexicon, morphology, syntax, semantics and pragmatics. Relates the lost linguistic abilities in these syndromes to properties of the brain.

Subject:
Applied Science
Arts and Humanities
Health, Medicine and Nursing
Life Science
Linguistics
Physical Science
Social Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Hirsch, Christopher
Wexler, Ken
Date Added:
09/01/2004
Abnormal Psychology
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CC BY-NC-SA
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Selection of reading resources for Abnormal Psychology courses.
These resources were compiled by Dr. Susan Harvey, Associate Professor at Delta College

Subject:
Life Science
Material Type:
Reading
Date Added:
07/16/2018
Abomasum - Anatomy & Physiology
Only Sharing Permitted
CC BY-NC-ND
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The abomasum is the fourth chamber in the ruminant. It functions similarly to the carnivore stomach as it is glandular and digests food chemically, rather than mechanically or by fermentation like the other 3 chambers of the ruminant stomach.

Subject:
Anatomy/Physiology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
WikiVet
Provider Set:
Anatomy & Physiology
Date Added:
02/05/2015
About ECG
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CC BY-NC
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This video explains electrocardiogram wave forms.

Subject:
Life Science
Material Type:
Lecture
Date Added:
06/24/2016
About the Bioscience Image Library
Unrestricted Use
Public Domain
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BCC Bioscience Image Library is a media file repository of images and video clips made freely available to the public, with special attention to the needs of educators and students in the biological sciences. The resources are licensed under Creative Commons 0. This means all content is free, with no restrictions on how the material may be used, reused, adapted or modified for any purposes, without restriction under copyright or database law.


This project was partially funded by a $20,000,000 grant awarded by the U.S. Department of Labor’s Employment and Training Administration, Grant # TC-26450-14-60-A-25. The product was created by the grantee and does not necessarily reflect the official position of the U.S. Department of Labor. The U.S. Department of Labor makes no guarantees, warranties, or assurances of any kind, express or implied, with respect to such information, including any information on linked sites and including, but not limited to, accuracy of the information or its completeness, timeliness, usefulness, adequacy, continued availability, or ownership.


If you have any questions contact professor Faye Reynolds at: bioimagesoer@gmail.com

Subject:
Education
Life Science
Material Type:
Diagram/Illustration
Lesson
Module
Author:
Fayette A. Reynolds M.S.
Date Added:
07/11/2022
Abrupt climate change, greenhouse gases, and the bipolar see-saw
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CC BY-NC-SA
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In this activity, students work with paleoclimate proxy data (d18O, CH4, CO2)from the Byrd and GISP2 ice cores to investigate millennial-scale climate changes during the Last Glacial/Deglacial time periods. Students must prepare a publication quality plot of the data and answer several questions about the similarities and differences between the time-series (north-south phasing, amplitude, symmetry) and use this information to assess the bipolar see-saw mechanism for abrupt climate changes. Students are encouraged to read two journal articles for more information and to synthesize their results with other information from lectures and earlier readings.

(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)

Subject:
Applied Science
Biology
Environmental Science
Life Science
Mathematics
Measurement and Data
Material Type:
Activity/Lab
Homework/Assignment
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Teach the Earth
Author:
Kathleen Johnson
Date Added:
08/28/2019
Academic Journal of Surgery
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CC BY-NC
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Academic Journal of Surgery (AJS) is the official scientific journal of Research Center for Improvement of Surgical Outcomes & Procedures (RCISOP) affiliated to Tehran University of Medical Sciences. AJS is an open access, peer-reviewed, and quarterly journal that considers for publication articles in all fields and specialties of surgery in English language. This journal has both online and print versions and no charges are levied for publication.

Currently, AJS is indexed and abstracted in: Citefactor, UlrichsWeb, Index Copernicus (IC), Directory of Research Journal Indexing (DRJI), Google Scholar, International Committee of Medical Journal Editors (ICMJE), Open Academic Journals Index (OAJI), Advanced Science Index (ASI), Unversal Impact Factor (UIF), Directory of Abstract Indexing for Journals (DAJI), JournalTOCs, Electronic Journal Library (EZB), Scientific Indexing Services (SIS), AcademicKeys, Research Bible, InfoBase Index, Cosmoc Impacr Factor, Scholar Steer, Magiran, and IranMedex.

AJS focuses on all fields and specialties of surgery including General Surgery, Orthopedic Surgery, Pediatric Surgery, Neurosurgery, Plastic Surgery, Cardiothoracic Surgery, Vascular Surgery, Endocrine Surgery, GI Surgery, Colorectal Surgery, Urology, Surgical Oncology, Radiology, Anaesthesia, Trauma Services, ENT, particularly about surgical practice and research. Content includes Original Articles, Systematic Review or Meta-Analysis, Review Articles, Case Reports, Letters to the Editor, Clinical Trials and Health Policy Challenge.

Subject:
Applied Science
Health, Medicine and Nursing
Life Science
Material Type:
Reading
Provider:
Tehran University of Medical Sciences
Date Added:
01/01/2014
Accessibility: Disabilities Treasure Hunt
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CC BY-NC-SA
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This is a treasure hunt game that simulates various disabilities and gives a sense of how frustrating non-accessible content can be for people with disabilities. Suitable for a general audience, no programming experience necessary.
An editable copy is also given, along with ideas about how to make it more accessible.

Subject:
Arts and Humanities
Education
Life Science
Physical Science
Social Science
Material Type:
Activity/Lab
Provider:
CUNY Academic Works
Provider Set:
Brooklyn College
Author:
Kletenik, Devorah
Date Added:
06/16/2022
Accessing InterPro programmatically
Unrestricted Use
CC BY
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This is the third and last part of a webinar series on InterPro which is held between May 6th 2020 and May 20th 2020.

InterPro is a database that helps users to understand the possible functions of proteins sequence by identifying what family it belongs to or what domains and motifs it contains. To deal with the growing volume of protein sequence data and an increasing demand to retrieve subsets of the data, often via programmatic access, the InterPro website has been entirely redesigned. It provides additional features and more flexibility in querying, presenting and retrieving data. The website relies on an Application Programming Interface (API) which can also be utilised by users for direct access to the data.

This webinar describes how the InterPro data is structured in the API, and how it could be accessed programmatically for further bioinformatics analyses.

You can access the slides via GitHub.

Who is this course for?
This webinar is aimed at scientists and bioinformaticians, with basic programming knowledge, who are interested in accessing the InterPro database programmatically.

Subject:
Applied Science
Life Science
Material Type:
Lecture
Provider:
EMBL-EBI
Date Added:
05/20/2020
Accessing Streamflow Data via the Worldwide Web
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CC BY-NC-SA
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This is a computer-based activity in which students retrieve data from websites maintained by the US Geological Survey (USGS) and the National Weather Service (NWS), and then use that data to test different hypotheses regarding streamflow and precipitation. Students import data from web sites into a spreadsheet program where they can construct scatter plots and perform simple statistical tests. The activity has two components, the first focusing on relations between streamflow and drainage basin characteristics (drainage area, slope, precipitation), the second focusing on trends in annual precipitation at two locations in the USA: Burlington, VT, and Boulder, CO. As part of the second component, students conduct a statistical test to determine if the long-term trends in precipitation are significant.

(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)

Subject:
Biology
Hydrology
Life Science
Mathematics
Measurement and Data
Physical Science
Statistics and Probability
Material Type:
Activity/Lab
Data Set
Interactive
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Teach the Earth
Author:
John Pitlick
Date Added:
08/18/2020