An integrated course stressing the principles of biology. Life processes are examined primarily at the molecular and cellular levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

This fill-in-the-blank timeline is a planning tool for teachers to use when figuring out when to begin the steps associated with conducting a two-generation artificial selection experiment using Fast Plants. Teachers preparing for any selection experiment will find this timeline helpful, including those planning for the AP Biology Lab 1 of Big Idea 1: Evolution, Artificial Selection.

The aim of the course has always been a practical one. We want to give students practice in performing the commonest techniques in molecular biology and genetic engineering as well as providing a good basic understanding of how the techniques worked. Though you won’t be doing the wet lab part of the course this semester, you will get some experience via simulations and other “lab exercises” and you will get plenty of experience in planning and designing constructs to answer biological questions. Part of our aim is to prepare students for a career in genetic engineering and this hasn’t changed.

The goal of the Genetic Origins Program is to allow students to use their own DNA variations (polymorphisms) as a means to explore our shared genetic heritage and its implications for human health and society. Genetic Origins focuses on two types of DNA variations: an Alu insertion polymorphism on chromosome 16 (PV92) and single nucleotide polymorphisms (SNPs) in the control region of the mitochondrial (mt) chromosome. With two alleles and three genotypes, PV92 is a simple genetic system that illustrates Mendelian inheritance on a molecular level. PV92 data is readily analyzed using population statistics. The mt control region is one of the simplest regions of human DNA to sequence. With a high mutation rate, the mt control region is the "classical" system for studying human and primate evolution. The Genetic Origins site and linked Bioservers site have all the information needed for students to perform the Alu and mt DNA experiments and analyze the results - including online protocols, reagents, animations and videos explaining key concepts, and database tools.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Obesity and metabolic disorders are abnormally high in the Middle East. According to the World Health Organization, approximately 41% of all deaths in Kuwait are caused by cardiovascular disease. And after the US, Kuwait is the nation with the highest rate of obesity in the world. While overeating and an increasingly sedentary lifestyle are partially to blame, they’re not the only culprits. A new study from the Dasman Diabetes Institute in Kuwait suggests that genetic adaptations once key to survival for Kuwaiti ancestors predispose today’s population to debilitating disease. Traits like insulin resistance and hypertension spell trouble for modern, largely sedentary humans. But for the nomadic forbearers of today’s Kuwaiti population, they offered an advantage. An active metabolism and high blood pressure stimulate the sympathetic nervous system’s “fight-flight-or-freeze” response, favoring survival under the harsh desert climate of the Arabian Peninsula..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The aphid -- one of the most common crop pests in the world -- has a weakness that scientists have now learned to exploit. When attacked by predators, the bugs release a pheromone to tell fellow insects to scatter. Biologists have proposed spraying these alarm pheromones directly on crops to prevent pest damage, but synthesis is costly. With the advent of genetic engineering, though, the cheaper option is to modify crops to produce the deterrents themselves. In 2015, biologists at Rothamsted Research, an agricultural research station in the UK, reported the first engineering feat of this kind in wheat. To make wheat release insect pheromones, the group inserted a gene from the peppermint plant, which allows plants to produce the appropriate chemical. Then, they tested whether the altered plants’ volatile compounds were capable of repelling the pests..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Genetic mutations provide valuable tools for analyzing biochemical pathways in yeast. In this module, students use deletion mutants to analyze the steps in methionine biosynthesis in Saccharomyces cerevisiae. At the end of this module, students will be able to:understand and use the correct genetic nomenclature for genes, proteins and mutant strainsexplain how genetic screens are used to isolate mutant strains with particular phenotypesdistinguish various met deletion strains by their ability to grow on selective media containing different sulfur sources and by their appearnace on indicator mediapredict how mutations in various MET  genes will affect the intracellular concentrations of intermediates in the methionine biosynthesis This module is part of a semester-long introductory lab class, Investigations in Molecular Cell BIology, at Boston College.

This course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease.

This activity begins with sections that help students to understand basic principles of genetics, including (1) how genotype influences phenotype via the effects of genes on protein structure and function and (2) how genes are transmitted from parents to offspring through the processes of meiosis and fertilization. Then, a coin flip activity models the probabilistic nature of inheritance and Punnett square predictions; this helps students understand why the characteristics of children in many real families deviate from Punnett square predictions. Additional concepts covered include polygenic inheritance, incomplete dominance, and how a new mutation can result in a genetic condition that was not inherited. This activity helps students meet the Next Generation Science Standards.

In this video collaboration from Khan Academy and 23andMe, you'll learn about the basics of cells, chromosomes, and the genes contained in your DNA.

In this video collaboration from Khan Academy and 23andMe, you'll learn about the basics of cells, chromosomes, and the genes contained in your DNA.

In this video collaboration from Khan Academy and 23andMe, you'll learn about the variations in human DNA called SNPs, and how they can be used to understand relationships between people.

In this video collaboration from Khan Academy and 23andMe, you'll learn about the variations in human DNA called SNPs, and how they can be used to understand relationships between people.

In this video collaboration from Khan Academy and 23andMe, you'll learn how chromosomes and genes are passed down from parent to child.

In this video collaboration from Khan Academy and 23andMe, you'll learn how chromosomes and genes are passed down from parent to child.

In this video collaboration from Khan Academy and 23andMe, you'll learn how your observable traits, or phenotypes, are the result of interactions between your genes and environment.

In this video collaboration from Khan Academy and 23andMe, you'll learn how your observable traits, or phenotypes, are the result of interactions between your genes and environment.

In this video collaboration from Khan Academy and 23andMe, you'll find out why women don't have a Y chromosome. Even with no Y, women can still learn about their paternal ancestry with genetic testing from services like 23andMe.

This site is an OER lab manual for a college level genetics course.

This document contains eight genetic problems with multiple parts.  These include crosses in which only one character are studied, crosses in which two characters are studied, crosses with multiple alleles, and crosses that are sex-linked.