This presentation discuss how important physical activity and sleep in children is if you want to prevent obesity and cardiovascular disease. We will present the main cross sectional results from the OPUS School Meal Study. The focus will be on screen time for children, the amount of moderate-to-vigorous physical activity (MVPA), and sleep time. We will also touch upon differences in boys and girls as well as week and seasonal patterns.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder, affecting over 25% of adults worldwide. It causes inflammation and other health conditions, including hepatocellular carcinoma (HCC), a leading cause of cancer-related death. Recently, researchers have looked toward the use of senolytic drugs as a promising treatment. Senolytic drugs selectively target aging cells that no longer divide, which are associated with NAFLD-induced HCC. In a recent study, mice were given low-dose diethylnitrosamine (DEN) and a high-fat diet (HFD) to induce NAFLD-induced HCC. These and normal (CTL) mice were treated with a mixture of two senolytic drugs, dasatinib and quercetin (D+Q). Unexpectedly, the D+Q cocktail had no effect or even worsened liver disease progression in the mice and slightly increased liver damage and tumor generation. The drug cocktail also did not reduce the number of aging cells in the mouse liver, as indicated by the genetic marker p16..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Obesity and type 2 diabetes are associated with significant health impacts and a decrease in quality of life. Ob/ob and db/db mice are frequently used to research these disorders. Ob/ob mice do not express leptin, a hormone released from fat cells, while db/db mice do not express its receptor. These mutations impair food intake and energy expenditure, which leads to fat mass gain. Despite targeting the same hormone-receptor pair, db/db mice are more diabetic than ob/ob mice. To investigate the mechanisms behind these differences, researchers recently examined the two lines in detail. They found that total fat mass was comparable but that fat mass distribution was different. They also found very distinct inflammatory profiles: ob/ob mice had more inflammation in the liver, whereas db/db mice had a higher inflammatory tone in the subcutaneous adipose tissue..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Mesenchymal stromal cells, or MSCs, regulate many functions critical to maintaining organ health. They do so by sending and receiving biochemical signals across short and long distances. How this signaling function is altered by disease, however, remains unclear. In a recent study, researchers examined how obesity in mice affects the signaling functions of MSCs from fat tissue and bone marrow. The proteins secreted by MSCs in mice fed a normal diet play a role in detoxification activity in response to toxic substances and drugs. They are also involved in bone, cartilage and fat development. Further analyses revealed that mouse MSCs participate in two major signaling pathways: platelet degranulation, where signaling molecules wrapped up in granules are deployed to regulate blood clotting and inflammation; and the insulin-like growth factor pathway, which regulates cell proliferation, survival, and metabolism. Comparing proteins secreted by MSCs in normal vs. obese mice revealed key differences..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Succinate is a metabolite and extracellular signal transductor with complex, but largely inflammatory, roles in the human body. Circulating succinate is elevated in patients with obesity and type 2 diabetes and has been linked to numerous complications. Both human cells and gut bacteria generate succinate, but how microbial succinate production impacts circulating levels and host health remains unclear. In a recent study, combined evidence from human patients and mice point to intestinal succinate as a key factor in obesity-related metabolic disturbances. Specifically, gut microbiota is identified as a relevant source of the high levels of circulating succinate found in obesity. However, modulation of intestinal flora dysbiosis of obese mice with succinate-consuming bacteria as a probiotic might reduce circulating succinate levels. Odoribacter laneus was a particularly promising candidate for this purpose. O..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Our Supersized Kids: Childhood Obesity

Childhood obesity is a crippling crisis of supersized proportions. During the past four decades, obesity rates have soared among all ages, but no more so than in children ages 6 to 11. Today, nearly a third of our children and adolescents are overweight or obese. And the numbers continue to rise.

KSPS's Our Supersized Kids delves into the issues causing the childhood obesity epidemic in the Pacific Northwest and around the country and what’s being done about it. Families struggling with obesity are profiled along with successful programs.

Use the video segments and discussion questions to help students explore the major causes of the childhood obesity epidemic and what can be done about it. Visit KSPS Education for additonal educator resources.

https://www.pbslearningmedia.org/resource/our-supersized-kids-childhood-obesity/our-supersized-kids-childhood-obesity/

Overview

Childhood obesity is a crippling crisis of supersized proportions. During the past four decades, obesity rates have soared among all ages, but no more so than in children ages 6 to 11. Today, nearly a third of our children and adolescents are overweight or obese. And the numbers continue to rise.

Our Supersized Kids delves into the issues causing the childhood obesity epidemic in the Pacific Northwest and around the country and what’s being done about it. Families struggling with obesity are profiled along with successful programs.

Grades: 3 and up

Subjects: Nutrition, Childhood Obesity, Health, Fitness

Standards: This learning resource guide is aligned to the Washington State K-12 Learning Standards for Health and Physical Education.

· Standard 1: Students will comprehend concepts related to health promotion and disease prevention to enhance health.
· Standard 2: Students will analyze the influence of family, peers, culture, media, technology, and other factors on health behaviors.
· Standard 4: Students will demonstrate the ability to use interpersonal communication skills to enhance health and avoid or reduce health risks.
· Standard 5: Students will demonstrate the ability to use decision-making skills to enhance health.
· Standard 7: Students will demonstrate the ability to practice health-enhancing behaviors and avoid or reduce health risks.

This course encompasses the study of eating as it affects the health and well-being of every human. Topics include taste preferences, food aversions, the regulation of hunger and satiety, food as comfort and friendship, eating as social ritual, and social norms of blame for food problems. The politics of food discusses issues such as sustainable agriculture, organic farming, genetically modified foods, nutrition policy, and the influence of food and agriculture industries. Also examined are problems such as malnutrition, eating disorders, and the global obesity epidemic; the impact of food advertising aimed at children; poverty and food; and how each individual's eating is affected by the modern environment.

Episode 1, part 1: Interview with Sir Michael Marmot, Professor of Epidemiology and Public Health at University College London about the current state of Global Health, with special focus on Health Equity. The first episode consists of two parts.
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The Swedish Global Health Podcast - A Podcast about Global Health and Sustainable Development is aimed at anyone interested in knowing more about this exciting topic! It is co-produced by the Swedish Society of Medicine's Committee for Global Health and the Swedish Society of Medicine's student and junior doctor section.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A fundamental law of genetics states that offspring do not inherit traits from their parents that were acquired in response to environmental conditions. Recent research in the field of epigenetics, however, is turning this principle on its head. Several recent studies have come to the remarkable conclusion that unhealthy diets in males can contribute to the development of metabolic diseases in their offspring. Even when those offspring are raised with healthy diets_._ Now, a study has identified small RNAs as the molecules responsible for the transmission of these disorders. For a long time scientists thought that inheritance of traits only occurred via DNA being passed from parent to offspring. It is now clear, however, that the experiences of one generation can have an effect on the next. When parents have a high-stress lifestyle or an unhealthy diet, for example, chemical modifications can occur on genes that are then passed to their children. This is termed ‘epigenetic inheritance..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A new clinical trial has shown promising results for those trying to shed excess pounds: researchers have zeroed in on a combination of herbal extracts that can significantly increase weight loss under the right circumstances. The news could mean better health for the more than 1 billion people who are overweight or obese worldwide. Traditional pharmaceutical and surgical options for weight management are expensive and often associated with adverse effects. The herbal formulation – composed of extracts from three common culinary spices used in Indian cooking – was developed as a high-quality natural alternative. The combination tackles excess body weight through a multi-layered approach, by both preventing fat cells from maturing and boosting existing fat break down. To determine the safety and efficacy of the extracts, researchers performed a randomized, double-blind, placebo-controlled clinical trial with healthy overweight adults..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The 'Western' diet is often associated with highly processed foods rich in fat and low in fiber, which can be bad for our metabolism. But unhealthy food choices can also affect our brain, resulting in neuroinflammation and cognitive impairment. In a new study using a mouse model of obesity, researchers evaluated the effect of fiber on cognition and brain function via the gut-brain axis. β-glucan, the major soluble fiber in oat and barley grains, was fed to the mice for 15 weeks. The addition of this fiber prevented diet-induced cognitive impairment in the obese mice and counteracted diet-induced activation of inflammatory cells called microglia in the brain. β-glucan also promoted signaling to create new synapses in the brain and reversed gut barrier dysfunction in the colon. These results highlight the impact that the Western diet has on the gut-brain axis and suggests that increasing consumption of β-glucan-rich foods may help attenuate diet-induced cognitive decline..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

توقف عن فرك يدك على الإيدز، السرطان وإنفلونزا الطيور. أمراض القلب والأوعية الدموية تقتل أكير من كل شيء آخر مجتمعين -- وهي في الغالب يمكن تجنبها. د/ دين أورنيش يشرح كيف يمكن لتغيير المظام الغذائي إنقاذ الأرواح.