In this subject, we consider two basic topics in cellular biophysics, posed here as questions:

Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential?
How are potentials generated across the membranes of cells? What do these potentials do?

Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the interplay between theory and experiment transcends the value of the specific knowledge gained in the subject matter.
This course is jointly offered through four departments, available to both undergraduates and graduates.

This course elaborates on the application of the principles of energy and mass flow to major human organ systems. It discusses mechanisms of regulation and homeostasis. It also discusses anatomical, physiological, and pathophysiological features of the cardiovascular, respiratory, and renal systems. There is emphasis on those systems, features, and devices that are most illuminated by the methods of physical sciences.

In this lesson the students will learn how the heart functions. Students will be introduced to the concept of action potential generation. The lesson will explain how action potential generation causes the electrical current that causes muscle contraction in the heart. Students will be introduced to the basic electrical signal generated by the heart; P, QRS, and T waves. The lesson will approach the heart from an engineering standpoint and encourage students to design ways to improve heart function. Students will also learn the basic steps of the engineering design process.

Systems Neuroscience Laboratory consists of a series of laboratories designed to give students experience with basic techniques for conducting systems neuroscience research. It includes sessions on anatomical, neurophysiological, and data acquisition and analysis techniques, and the ways these techniques are used to study nervous system function. Training is provided in the art of scientific writing with feedback designed to improve writing skills. Assignments include weekly preparation for lab sessions, two major research reports and a series of basic computer programming tutorials (MATLAB). The class involves the use of experimental animals. Enrollment is limited.