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  • natural-products
Metabolomic analysis differentiates chemicals produced by sponges and symbiotic microbes
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Sponges are a diverse group of aquatic animals with porous bodies that produce a vast array of natural products, some with important medicinal properties, but their porous body structure also provides ample habitat for symbiotic microorganisms, which can account for up to 35% of their total body weight. Previous studies looking at the unique natural products produced by sponges have rarely taken this close relationship into account, making the extent to which microorganisms actually produce them unclear. To fill this gap, a team of researchers identified the chemical compounds found in the tissues of six sponge species from the Great Barrier Reef and their symbiotic microbes. Several compounds with potential roles in competition and defense against intruding organisms and oxidative stress were specifically attributed to the microbial cells, while the compounds produced by the sponge tissues may provide nutrients to the symbiotic microorganisms and aid in sponge defense..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/18/2022
Microbial Megaproducers: Discovery, Biosynthesis, Engineering and Applications of Natural Products
Conditional Remix & Share Permitted
CC BY-NC-SA
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The natural world is a mega-factory of small molecules, peptides, fatty acids, phospholipids, and a host of other compounds, known as natural products (NPs). Immensely diverse in structure and function, NPs have strongly influenced how we treat infectious disease, cancer, pain, and a host of other conditions. Roughly half of the drugs that have been approved in the past 30 years are NPs, derivatives of NPs or NP-inspired. In this discussion-based course, we will delve into research on discovering NPs from producing organisms, investigating the biochemistry of NP production, and using synthetic biology to create NP derivatives—all with a particular emphasis on how genomic data guides and informs all these studies.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subject:
Applied Science
Biology
Chemistry
Engineering
Health, Medicine and Nursing
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Hetrick, Kenton
Ulrich, Emily
Date Added:
09/01/2020
Plantas Medicinais - Cordel
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CC BY
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Aqui é apresentado um cordel construído por discentes da Escola Estadual Presidente Arthur da Costa e Silva, Gerência da Regional de Educação Recife Sul (GRE-Recife Sul), Pernambuco, Localizado no Bairro da Mustardinha, Zona Sul do Recife-PE. Este trabalho faz parte da dissertação de Mestrado de Vilmar da Silva Nascimento, que teve como título: "Revitalização de hortas escolares com plantas medicinais como cenário pedagógico". Sob a orientação do prof. Dr. Paulo Euzébio Cabral Filho e co-orientação de Valéria Sandra de Oliveira Costa do Programa de Mestrado Profissional em Rede Nacional para o Ensino das Ciências Ambientais (ProfCiAmb) pólo UFPE. 

Subject:
Health, Medicine and Nursing
Material Type:
Reading
Author:
Paulo Cabral Filho
Vilmar Silva Nascimento
Valéria Sandra de oliveira Costa
Date Added:
09/26/2021