This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Some pain after a major operation is expected -- but some patients suffer more than others. More than 60% of surgical patients have moderate-to-severe postoperative pain, potentially predisposing them to persistent postsurgical pain. But who falls into which category? To better predict patients’ pain -- and thereby provide better treatment -- researchers at the University of Florida studied a large group of surgical patients to identify different pain trajectories. The team’s work published in _Anesthesiolog_y revealed five distinct patterns determined in large part by patient-specific factors such as age, sex, and psychologic features. The researchers monitored patents’ pain reports for 7 days in 360 patients recovering from a variety of different surgeries. Pain was evaluated using the [Brief Pain Inventory], which asks for a patient’s average, worst, and least pain in the last 24 hours on a scale from zero to 10..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"In ecology research, population density is an important metric for community analysis studies. Yet even though microbiomes are small ecosystems, microbiome studies rarely report the bacterial density. To evaluate the significance of bacterial density in gut microbiome research, a recent retrospective study examined rectal swabs from hospitalized patients. The authors found that bacterial density had important methodologic significance, as it predicted vulnerability to sequencing contamination. Specifically, low-bacterial-density specimens had higher levels of sequencing contamination. Clinical factors like age, exposure to antibiotics, and comorbidities also varied with bacterial density. Older patients and those with multiple co-morbidities had high bacterial density, while antibiotic exposure correlated with low density. Lastly, bacterial density showed potential as a prognostic indicator, as the density at time of admission correlated with subsequent infection..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Evidence-based clinical aspects of audiologic identification, assessment, intervention, and prevention of hearing impairments relevant to the practice of speech-language pathology; strategies for working with individuals and their families across the lifespan; culturally and linguistically appropriate practice.

The target learner will have started in a dental hygiene program and have basic knowledge of common medical emergencies that may occur in the dental office. As a dental hygiene student, this lesson will enhance the learner's knowledge on basic emergency drug use as a dental hygienist in a clinic. Ideally, the learner would have completed the lesson regarding emergency drugs in their pharmacology course and can utilize this lesson as a supplement to self refelect on their retention of knowledge and key take aways.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Exosomes are tiny membrane-bound vesicles that could be cutting-edge tools for cancer diagnosis and treatment. Exosomes are released by nearly every cell type to transport biomolecule cargo between cells and can be found in most body fluids. Among exosome cargos, microRNAs have draw significant attention for their role in the development of various diseases. MicroRNAs are small non-coding RNA molecules that can regulate the expression of protein-encoding genes. Exosomal microRNAs have shown promise as diagnostic biomarkers and as therapeutic targets or even therapeutics themselves. Studies have suggested that the microRNAs in cancer cell exosomes resemble the microRNA pool from their parent cancer cell. Exosomal microRNAs may be of particular use for the detection and treatment of hematologic neoplasms, which include cancers like lymphoma and multiple myeloma. However, there are several barriers than need to be addressed before exosomal microRNAs can be used in clinical settings..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"An effective, tightly regulated immune response is critical for patients to recover from viral infections like COVID-19. Understanding immune regulation can allow researchers to develop better therapeutics and management techniques for patients. One class of factors involved with immune regulation are soluble immune mediators, which play roles in the dynamic interactions between ligands and membrane-bound receptors. Normally, soluble immune mediators help maintain and restore health after pathological events, but sometimes their dysregulation causes pathology instead. SARS-CoV-2 infection impacts many of these soluble immune mediators and, through them, many physiological processes. Thus, dysregulated shifts in the concentration of some of these molecules could be playing a significant role in COVID-19 severity and mortality..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This includes an instruction page on how students that reach a healthcare capstone course in high school are to complete their weekly journal assignments for the class.    Each week when the students are experiencing a different location or department this provides a reflection as their summative for the weekly clinical experience.   The journal includes students reflecting on: professions, pathologies, treatment/cures, and overall experiences.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Extracellular vesicles (EVs) are small membrane-bound structures released by cells into the surrounding environment. EVs carry various biomolecules including proteins, DNA, RNA, and lipids and play critical roles in intercellular communication, including influencing the behavior and function of recipient cells. EVs have great potential in the clinical environment as diagnostic markers, treatment delivery vehicles, or therapeutic targets. However, to best utilize them researchers need to understand the mechanisms influencing EVs. Significant progress has been made in understanding the factors that regulate communication between cells via EVs, but there is still much to learn about what regulates EV targeting and uptake by recipient cells. Also, little is currently known about cargo release and relocation within the recipient cell. This is due to the extremely small size of EVs and a lack of imaging technology to visualize them..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Spinal cord stimulation offers long-term relief to patients managing chronic pain, without the need for opioids. This winning combination has spurred incredible growth in the industry, with approximately 50,000 spinal cord stimulators being implanted each year and an estimated market of 7 billion U.S. dollars by 2020. But despite this progress, exactly how the technology works remains unclear. Especially with regard to potential changes in brain activity. A new review article in the journal Anesthesiology takes a closer look at these potential supraspinal pathways and actions. Covering both preclinical and clinical articles, the review starts with the 1960s, when an idea known as Gate Control Theory was proposed to explain how conventional tonic stimulation works. The theory suggests that a combination of presynaptic inhibition and inhibitory interneuronal communication occurs in the spinal cord following the electrical activation of large-diameter afferent fibers..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Advancements in next-generation sequencing have opened the door to detailed analyses of the human microbiome. This technique has many applications, and pancreatic cancer research is one of them. Pancreatic cancer is a devastating disease with an estimated 5-year survival rate of only 11%. Most cases, over 80%, are not found until the cancer is too advanced to successfully treat, but pancreatic cancer patients show shifts in their oral microbiome, which could be detected years earlier than current methods allow. Pathogenic oral bacteria have also been found within pancreatic tumors, which is another potential link between them. However, these findings barely scratch the surface of how the oral microbiome relates to pancreatic cancer. The oral microbiome is influenced by a combination of host-related and environmental factors, which include genetics, race, ethnicity, smoking, socioeconomics, and age..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.