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Alcoholic Fermentation in Yeast
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Students learn about the basics of aerobic cellular respiration and alcoholic fermentation and design and carry out experiments to test how variables such as sugar concentration influence the rate of alcoholic fermentation in yeast. In an optional extension activity students can use their yeast mixture to make a small roll of bread.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Breathing and Holding Your Breath
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Students begin with interactive activities to develop a basic understanding of why cells need oxygen and need to get rid of carbon dioxide, how the circulatory and respiratory systems cooperate to bring oxygen and remove carbon dioxide from cells all over the body, and how the nervous system regulates breathing. Then, students carry out an experiment to test whether changing levels of oxygen and carbon dioxide influence how long they can hold their breath.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Cell Structure and Function Lessons
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This overview presents key concepts that students often do not learn from standard textbook presentations and suggests a sequence of learning activities to help students understand how the parts of a cell work together to accomplish the multiple functions of a dynamic living cell. Suggested activities also reinforce student understanding of the relationships between molecules, organelles and cells, the diversity of cell structure and function, and the importance and limitations of diffusion. This overview provides links to Web resources, hands-on activities and discussion activities.

Subject:
Life Science
Material Type:
Activity/Lab
Game
Lesson Plan
Unit of Study
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Cell Vocabulary Review Game
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This game helps students to enjoy reviewing vocabulary related to cells, organelles, and the plasma membrane. Each card in the deck has a target vocabulary word and two related taboo words that the student may not use when giving clues so the other students in his or her small group can guess the target word. Many students have trouble learning the substantial new vocabulary required for biology, and this game lets students have fun while reinforcing their understanding of key terms.

Subject:
Life Science
Material Type:
Game
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Cells As Molecular Factories
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This minds-on analysis and discussion activity reviews how eukaryotic cells are molecular factories in two senses: cells produce molecules and cells are made up of molecules. The questions guide students to think about how the different parts of a eukaryotic cell cooperate to function as a protein-producing factory and as a recycling plant. Additional questions require students to identify the locations and functions of different types of molecules in eukaryotic cells.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Cellular Respiration and Photosynthesis Lessons
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This overview of energy, cellular respiration and photosynthesis summarizes important concepts and common misconceptions. It also suggests a sequence of learning activities to overcome misconceptions, develop student understanding of important concepts, and relate these concepts to familiar topics such as breathing, food, body weight, and plant growth.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Unit of Study
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
DNA
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DNA
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In this activity, students extract DNA from their cheek cells and relate the steps in the procedure to the characteristics of cells and biological molecules. Students learn key concepts about the function of DNA during the intervals required for the extraction procedure. A second optional section develops student understanding of the fundamentals of DNA structure, function and replication; this section includes hands-on modeling of DNA replication. This activity, together with our activity, "From Gene to Protein - Transcription and Translation", can be used to teach the basic concepts of molecular biology.

Subject:
Life Science
Material Type:
Activity/Lab
Data Set
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
DNA Structure, Function and Replication
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This analysis and discussion activity can be used to introduce your students to key concepts about DNA structure, function and replication or to review these topics. This activity includes hands-on modeling of DNA replication.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Diffusion across a Selectively Permeable Membrane
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Students investigate the effects of molecule size on diffusion across a synthetic selectively permeable membrane. This investigation includes observation and analysis of osmosis (diffusion of water across a selectively permeable membrane). Additional questions guide students in analyzing the relative advantages of different types of model of the cell membrane.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Diffusion and Cell Size and Shape
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This minds-on analysis and discussion activity helps students understand that cell size is limited by the very slow rate of diffusion over any substantial distance and the insufficient surface-area-to-volume ratio for larger cells. In addition, students calculate why these problems do not apply to long slender cells or parts of cells (e.g. the axons of neurons that extend from your spinal cord to your foot). To maximize student participation and learning, I recommend that you have your students complete the questions individually or in pairs and then have a whole class discussion.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Dragon Genetics -- Independent Assortment and Gene Linkage
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Students learn the principles of independent assortment and gene linkage in activities which analyze inheritance of multiple genes on the same or different chromosomes in hypothetical dragons. Students learn how these principles derive from the behavior of chromosomes during meiosis and fertilization.

Subject:
Life Science
Genetics
Material Type:
Activity/Lab
Lesson Plan
Simulation
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Dragon Genetics -- Understanding Inheritance
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In this simulation activity students mimic the processes of meiosis and fertilization to investigate the inheritance of multiple genes and then use their understanding of concepts such as dominant/recessive alleles, incomplete dominance, sex-linked inheritance, and epistasis to interpret the results of the simulation. This activity can be used as a culminating activity after you have introduced classical genetics, and it can serve as formative assessment to identify any areas of confusion that require additional clarification.

Subject:
Life Science
Genetics
Material Type:
Activity/Lab
Lesson Plan
Simulation
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Bob Farber
Enzymes Help Us Digest Food
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Experiments with the enzyme lactase and discussion questions help students to learn about enzyme function, enzyme specificity, and the molecular basis of lactose intolerance. Students also learn about the scientific method by interpreting evidence to test hypotheses and designing the second and third experiments to answer specific scientific questions about lactase. (An alternative version of the Student Handout gives specific instructions for all three of the experiments.)

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Evolution and Adaptations
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In common experience, the term "adapting" usually refers to changes during an organism's lifetime. In contrast, evolutionary biologists use the term "adaptation" to refer to a heritable trait that increases fitness. To help students reconcile these different concepts, this activity introduces the concept of phenotypic plasticity (the ability of an organism to adapt to different environments within its lifetime). Questions guide students in analyzing how the balance between the advantages and disadvantages of a characteristic (e.g. an animal's color) can vary in different circumstances, how phenotypic plasticity can be a heritable trait that can optimize fitness in a variable environment, and how natural selection can influence the amount of phenotypic plasticity in a population. This activity is designed to help high school students meet the Next Generation Science Standards and the Common Core State Standards.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Evolution by Natural Selection
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Principles of natural selection are demonstrated by a simulation that involves different color pom-poms and student feeders equipped with different types of feeding implements. Students analyze results to see how different traits contribute to fitness in different habitats. Additional examples and questions help students to understand the process of natural selection, including three necessary conditions for natural selection to take place.

Subject:
Life Science
Material Type:
Activity/Lab
Interactive
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Food, Energy and Body Weight
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This minds-on analysis and discussion activity helps students to understand the relationships between food molecules as a source of energy, cellular respiration, physical activity, and changes in body weight.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
From Gene to Protein -- Transcription and Translation
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In this hands-on activity students learn how a gene provides the instructions for making a protein, and how genes can cause albinism or sickle cell anemia. Simple paper models are used to simulate the molecular processes of transcription and translation. This activity can be used to introduce students to these topics or to reinforce student understanding. In addition, students evaluate the advantages and disadvantages of different types of models included in this activity.

Subject:
Life Science
Material Type:
Activity/Lab
Interactive
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Genetic Engineering Challenge - Preventing Vitamin A Deficiency
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"Genetic Engineering Challenge - How can scientists develop a type of rice that could prevent vitamin A deficiency?" is an analysis and discussion activity. This activity begins with an introduction to vitamin A deficiency, rice seeds, and genetic engineering. Next, several questions challenge students to design a basic plan that could produce a genetically engineered rice plant that makes rice grains that contain pro-vitamin A. Subsequent information and questions guide students in developing an understanding of the basic techniques of genetic engineering. Students use fundamental molecular biology concepts as they think about how to solve a practical problem. This activity can be used to introduce students to genetic engineering or to reinforce basic understanding of genetic engineering.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Genetics
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This activity helps students to understand basic principles of genetics, including relationships of genotype to phenotype, concepts of recessive and dominant alleles, and how understanding meiosis and fertilization provides the basis for understanding inheritance, as summarized in Punnett squares. The Student Handout includes an analysis of the inheritance of albinism that teaches all of these concepts, a Coin Toss Genetics activity that helps students understand the probabilistic nature of Punnett square predictions, and an analysis of the inheritance of sickle cell anemia that reinforces the basic concepts and introduces some of the complexities of genetics. The Genetics Supplement includes two additional activities, an analysis of student data on the sex makeup of sibships and pedigree analyses of recessive and dominant alleles with challenge questions that introduce the role of mutations and an evaluation of Punnett squares and pedigrees as models of inheritance.

Subject:
Life Science
Genetics
Material Type:
Activity/Lab
Lesson Plan
Simulation
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Scott Poethig
Genetics Concepts and Activities
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These lessons demonstrate how a good understanding of mitosis, meiosis and fertilization and a basic understanding of the roles of DNA and proteins can provide the basis for understanding genetics. Important genetics concepts for students to learn are summarized and multiple learning activities are suggested to help students understand Punnett squares, pedigrees, dominant/recessive alleles, X-linked recessive alleles, incomplete dominance, co-dominance, test crosses, independent assortment, genetic linkage, polygenic inheritance, etc. This overview provides links to suggested activities which include hands-on simulation and laboratory activities, analysis of class data, review games and discussion activities and questions.

Subject:
Life Science
Genetics
Material Type:
Activity/Lab
Game
Lesson Plan
Unit of Study
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Genetics Vocabulary Review Game
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Rating

This game helps students to enjoy reviewing genetics vocabulary. Each card in the deck has a target vocabulary word and two related taboo words that the student may not use when giving clues so the other students in his or her small group can guess the target word. Many students have trouble learning the substantial new vocabulary required for biology, and this game lets students have fun while reinforcing their understanding of key terms.

Subject:
Life Science
Genetics
Material Type:
Game
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Get the Lead Out! Game
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This board game reinforces learning about the sources and biological hazards of lead exposure. The first file has the game and the second file has teacher notes, including background information on lead.

Subject:
Life Science
Material Type:
Game
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Edison Freire
Ingrid Waldron
Golden Rice - Evaluating the Pros and Cons
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This activity engages students in evaluating the evidence and arguments related to Golden Rice and other possible strategies for preventing vitamin A deficiency. Students use this information to develop evidence-based conclusions about Golden Rice and the prevention of vitamin A deficiency. Students also develop questions that could provide important additional information for evaluating the arguments in favor of and opposed to Golden Rice and related policy proposals. In addition, students analyze how two reasonably accurate articles can present totally opposing points of view on this complex policy issue.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
HIV/AIDS - Molecular and Evolutionary Biology
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This analysis and discussion activity introduces students to the biology of HIV infection and treatment, including the molecular biology of the HIV virus life cycle and the importance of understanding molecular biology and natural selection for developing effective treatments. The questions in this activity challenge students to apply their understanding of basic molecular and cellular biology and natural selection and interpret the information presented in prose and diagrams in order to understand multiple aspects of the biology of HIV/AIDS and treatment.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Hands-on Activities for Teaching Biology
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These hands-on, minds-on activities engage students in experiments or simulation activities and incorporate multiple questions designed to foster student understanding of important concepts in the life sciences. Topics covered include biological molecules, diffusion, metabolism, cell division, genetics, molecular biology, evolution, diversity, human physiology and design and interpretation of experiments. These activities were designed for teaching high school or middle school students, but many of these activities can also be used in non-major introductory college biology classes. To accommodate limited budgets, most of these activities can be carried out with minimum equipment and expense for supplies. Additional minds-on activities for teaching biology, including discussion activities, are available at http://serendip.brynmawr.edu/exchange/bioactivities. Most of the activities are described in student handouts and teacher notes; the student handouts are available as Word files for teachers to customize for their students.

Subject:
Life Science
Material Type:
Activity/Lab
Interactive
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
How Do Biological Organisms Use Energy?
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This analysis and discussion activity is designed to help students understand the basic principles of how biological organisms use energy, with a focus on the roles of ATP and cellular respiration. This activity provides a useful basic understanding of cellular respiration and provides an important conceptual framework for students who will be learning the complex specifics of cellular respiration. This activity concludes with a brief introduction to two important principles: conservation of energy and the inefficiency of energy transformations.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
How Mistakes in Cell Division Can Result in Down Syndrome and Miscarriages
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This analysis and discussion activity reinforces student understanding of the process of meiosis and the importance of having exactly the right number of copies of each chromosome in our body's cells. This activity also helps students to understand that miscarriages are often the result of genetic abnormalities and that genetic conditions sometimes are not inherited (e.g. Down syndrome due to meiotic nondisjunction). Optional additional questions can be used to promote student understanding of sex chromosome abnormalities and X chromosome inactivation.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
How could complex eyes have evolved?
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This analysis and discussion activity introduces students to evidence from comparative anatomy, mathematical modeling, and DNA analysis. This evidence suggests a sequence of steps that appear to have contributed to the evolution of the human eye. Questions in the Student Handout guide students in analyzing this evidence, evaluating whether the similarities between human and octopus eyes are due to convergent evolution and/or common descent with modification, and understanding the role of gene duplication in evolution. This activity is designed to help high school students meet the Next Generation Science Standards and the Common Core State Standards.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Introduction to Osmosis
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This activity begins with a student investigation of the phenomenon of osmosis and then moves to analysis of the mechanism and implications of osmosis. In Part I, "What is happening to these eggs?" students observe and analyze the effects of osmosis on eggs. In Part II, "Understanding Osmosis", analysis and discussion questions introduce students to the molecular basis for osmosis and challenge students to apply their understanding of osmosis to several real-world phenomena.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Amy Dewees
Ingrid Waldron
Invertebrate Diversity
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In this introduction to invertebrate diversity, students compare the external anatomy and locomotion of earthworms, mealworms, crickets and crayfish, all of which can be purchased at low cost from local pet stores. Discussion questions help students understand the evolutionary basis of observed similarities and differences. This activity can be used as an introduction to the Annelid and Arthropod phyla and the principle that form matches function.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Minds-On Activities for Teaching Biology
Conditions of Use:
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Rating

These minds-on activities include analysis and discussion activities, experiments, and simulation activities to foster student understanding of important concepts in the life sciences. Topics covered include biological molecules, membranes and osmosis, cellular respiration and photosynthesis, cell structure and function, cell division, genetics, molecular biology, evolution, diversity, human physiology and health, and design and interpretation of experiments. These activities were designed for teaching high school and middle school students, but many of them can also be used in non-major introductory college biology classes. Most of the activities are described in student handouts and teacher notes; the student handouts are available as Word files for teachers to customize for their students. The hands-on experiments and simulation activities are available at http://serendip.brynmawr.edu/sci_edu/waldron/. To accommodate limited budgets, most of the hands-on activities can be carried out with minimum equipment and expense for supplies.

Subject:
Life Science
Material Type:
Activity/Lab
Game
Interactive
Lecture Notes
Lesson Plan
Unit of Study
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Mitosis, Meiosis and Fertilization
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Students use model chromosomes to simulate the processes of mitosis, meiosis and fertilization, and they answer questions designed to promote understanding of these processes. To demonstrate the principle that genes are transmitted from parents to offspring through the processes of meiosis and fertilization, students follow two alleles of a gene through gametes to zygotes as they model meiosis and fertilization. Students also learn how a mistake in meiosis can result in Down Syndrome.

Subject:
Life Science
Material Type:
Activity/Lab
Interactive
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Lori Spindler
Scott Poethig
Mitosis, Meiosis and Fertilization Lessons
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These teacher notes summarize important concepts for students to understand concerning mitosis and meiosis, including the principle that understanding meiosis and fertilization provides the basis for understanding the fundamentals of inheritance. The proposed sequence of learning activities will help students understand and learn these major concepts and progress beyond common misconceptions. This overview provides links to suggested activities which include a hands-on simulation of mitosis meiosis and fertilization, a card sort of activity, a vocabulary review game and discussion questions.

Subject:
Life Science
Material Type:
Activity/Lab
Game
Lesson Plan
Unit of Study
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Mitosis, Meiosis and Fertilization Vocabulary Review Game
Conditions of Use:
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Rating

This game helps students to enjoy reviewing vocabulary related to mitosis, meiosis and fertilization. Each card in the deck has a target vocabulary word and two related taboo words that the student may not use when giving clues so the other students in his or her small group can guess the target word. Many students have trouble learning the substantial new vocabulary required for biology, and this game lets students have fun while reinforcing their understanding of key terms.

Subject:
Life Science
Material Type:
Game
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty
Mitosis and Meiosis Card Sort
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Rating

This minds-on activity is designed to help students review the processes of mitosis and meiosis and to ensure that students understand how chromosomes move during mitosis vs. meiosis. Students arrange the cards from a shuffled deck of the stages of mitosis and meiosis in the sequence of steps that occur during cell division by mitosis and another sequence of steps that occur during cell division by meiosis.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Moldy Jell-O
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Rating

Students design experiments to determine how substrate and environmental conditions influence growth of common molds. Students carry out their experiments, analyze and interpret their evidence, and prepare a report.

Subject:
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Jennifer Doherty