Keywords: Thymus (8)

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Fighting Back! (Lesson)
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Fighting Back! (Lesson)

This lesson describes the major components and functions of the immune system ... (more)

This lesson describes the major components and functions of the immune system and the role of engineers in keeping the body healthy (e.g., vaccinations and antibiotics, among other things). This lesson also discusses how an astronaut's immune system is suppressed during spaceflight due to stress and other environmental factors. (less)

Subject:
Mathematics and Statistics
Science and Technology
Engineering
Life Science
Space Science
Material Type:
Activities and Labs
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denali Lander
Integrated Teaching and Learning Program,
Janet Yowell
Malinda Schaefer Zarske
TeachEngineering.org
Teresa Ellis
Foxp3 Is Required Throughout the Life of a Regulatory T Cell
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Foxp3 Is Required Throughout the Life of a Regulatory T Cell

The forkhead family transcription factor Foxp3 is critical for the development and ... (more)

The forkhead family transcription factor Foxp3 is critical for the development and function of CD4+CD25+ regulatory T cells (Tregs). A series of reports have begun to shed light on the precise role of Foxp3 in the regulation of the Treg transcriptome. Foxp3 can bind to specific gene elements, thereby altering transcription of target genes directly, and Foxp3 can alter the expression of genes encoding other transcription factors, thereby having an indirect effect on the transcription of target genes. Cells retaining aspects of Treg differentiation persist in the absence of Foxp3, which is suggestive of a Foxp3-independent aspect of Treg biology. (less)

Subject:
Life Science
Material Type:
Activities and Labs
Images and Illustrations
Instructional Material
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David M. Soper (University of Washington School of Medicine;Department of Immunology REV)
Jared E. Lopes (University of Washington School of Medicine;Department of Immunology REV)
Steven F. Ziegler (University of Washington School of Medicine;Department of Immunology REV)
Human Embryology Animations
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Human Embryology Animations

A set of animations showing changes during cardiovascular, head & neck, and ... (more)

A set of animations showing changes during cardiovascular, head & neck, and gut, with limb and urogenital development coming soon. Currently includes a pre and post tests on each segment so students can assess their learning. (less)

Subject:
Life Science
Education
Material Type:
Assessments
Instructional Material
Reference
Simulations
Student Guide
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
PhD Valerie Dean O'Loughlin (Indiana University Medical Sciences Program)
T Cells

T Cells

T cells are so named as they differentiate in the thymus. They ... (more)

T cells are so named as they differentiate in the thymus. They are long lived and are involved in cell mediated immunity. They represent 60-80% of the circulating lymphocytes and all express the markers CD2, CD3 and CD7 as well as having T cell receptors (TCR). Each T cell has 30,000 TCRs each of which is identical and recognises antigens and major histocompatability complex (MHC) II. (less)

Subject:
Life Science
Material Type:
Images and Illustrations
Readings
Provider:
WikiVet
Provider Set:
Blood
Thymus - Anatomy & Physiology

Thymus - Anatomy & Physiology

The thymus has a key role in the maturation of prothymocytes into ... (more)

The thymus has a key role in the maturation of prothymocytes into mature T cells. In juvenile animals the thymus produces significant numbers of new T lymphocytes but as the animal matures this production decreases and T cell population is maintained by division of mature T cells. (less)

Subject:
Life Science
Material Type:
Images and Illustrations
Readings
Provider:
WikiVet
Provider Set:
Anatomy & Physiology
To Be or Not to Be a Treg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms
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To Be or Not to Be a Treg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms

Regulatory T (Treg) cells are a unique CD4+ T cell lineage that ... (more)

Regulatory T (Treg) cells are a unique CD4+ T cell lineage that plays a crucial role in the maintenance of immunological tolerance. The Forkhead box transcription factor Foxp3 is critically involved in Treg cell development and responsible for determining the suppressive function of these cells. The majority of Foxp3+ Treg cells are generated during T cell development within the thymus and show features of a stable T cell lineage. New work indicates that both induction and stabilization of Foxp3 expression are under epigenetic control, which suggests that selective interference with the underlying chromatin remodeling mechanisms might enable the development of future therapeutic strategies targeting Treg cells. (less)

Subject:
Life Science
Education
Material Type:
Activities and Labs
Images and Illustrations
Instructional Material
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Aras Toker (Helmholtz Centre for Infection Research;Experimental Immunology REV)
Jochen Huehn (Helmholtz Centre for Infection Research;Experimental Immunology REV)
Unlocking the Endocrine System
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Unlocking the Endocrine System

Students learn how the endocrine system works and compare it to the ... (more)

Students learn how the endocrine system works and compare it to the mail delivery system. Students discuss the importance of communication in human body systems and relate that to engineering and astronauts. (less)

Subject:
Mathematics and Statistics
Science and Technology
Engineering
Life Science
Space Science
Education
Material Type:
Activities and Labs
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Abigail Watrous
Integrated Teaching and Learning Program,
Janet Yowell
Malinda Schaefer Zarske
TeachEngineering.org
Visualizing and quantifying the suppressive effects of glucocorticoids on the tadpole immune system in vivo
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Visualizing and quantifying the suppressive effects of glucocorticoids on the tadpole immune system in vivo

This article presents a laboratory module developed to show students how glucocorticoid ... (more)

This article presents a laboratory module developed to show students how glucocorticoid receptor activity can be pharmacologically modulated in Xenopus laevis tadpoles and the resulting effects on thymus gland size visualized and quantified in vivo. (less)

Subject:
Life Science
Material Type:
Activities and Labs
Instructional Material
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Alexander Schreiber (St. Lawrence University)
2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni ... (more)

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni smelborp gnivlos rof seuqinhcet gnipoleved no si sisahpmE .scipot decnavda detceles dna scihparg retupmoc ,gnihcraes dna gnitros ,serutcurts atad ,sdohtem laciremun ,secafretni resu lacihparg ,stpecnoc gnimmargorp revoc smelborp gnimmargorp ylkeeW .esruoc eht fo sucof eht si tnempoleved dna ngised erawtfos detneiro-tcejbO .snoitacilppa cifitneics dna gnireenigne rof sdohtem lanoitatupmoc dna tnempoleved erawtfos latnemadnuf stneserp esruoc sihT (less)