Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Describe the structure of eukaryotic cellsCompare animal cells with plant cellsState the role of the plasma membraneSummarize the functions of the major cell organelles

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Critical defects that compromise the nucleus during cell division could be the basis for the age-accelerating effects of people living with progeria. Hutchinson-Gilford progeria syndrome is a genetic disorder that causes premature aging. Affecting one in 8 million newborns worldwide, the disorder is extremely rare—and fatal. The rapid aging of the cardiovascular system causes death due to heart attack or stroke in patients by their mid-teens. Progeria is caused by a tiny point mutation in the lamin A gene. This gene is responsible for producing structural proteins called lamins, which form the scaffolding that holds the cell nucleus together. The mutated form of prelamin A called progerin destabilizes the cell nucleus—the genetic control center of cells. The result is the fast-aging effects observed in progeria. But the link from gene mutation to physical disorder has remained a mystery. Previous studies have looked only at models of progeria, not at actual patient cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The trafficking of proteins into and out of the nucleus is central to cell function In fruit flies, the process also seems to determine the fate of neural stem cells in the larval central brain Neural stem cells are essential to neurogenesis, a two-step process in Drosophila The cells first form during embryogenesis At the end of neurogenesis, the cells divide terminally and exit the cell cycle, producing new neurons A build up of the protein Prospero in the nucleus initiates this exit But what causes this accumulation? Researchers report that Prospero uses RanGAP to shuttle across the nuclear envelope Eliminating RanGAP function doesn’t affect the nuclear import of Prospero, but rather its export out of the nucleus This suggests a drop in RanGAP levels could entrap Prospero in the nucleus, hinting that an intrinsic mechanism determines the fate of neural stem cells in Drosophila and perhaps other organisms as well Wu, D., et al..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.