Keywords: Hardy-Weinberg Equilibrium (8)

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AP Investigative labs: An inquiry-base Approach Lab 2: Mathematical Modeling: Hardy-Weinberg
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AP Investigative labs: An inquiry-base Approach Lab 2: Mathematical Modeling: Hardy-Weinberg

In this lab, students will use mathematical methods to build a spreadsheet ... (more)

In this lab, students will use mathematical methods to build a spreadsheet that models how a hypothetical gene pool changes from one generation to the next. The second part of the investigation asks the students to generate their own questions regarding the evolution of allele frequencies in a population. Then students will explore possible answers to those questions by applying more sophisticated computer models. This investigation also provides an opportunity for students to review concepts including natural selection as the major mechanism of evolution; the relationship among genotype, phenotype, and natural selection; and fundamentals of classic Mendelian genetics. (less)

Subject:
Life Science
Material Type:
Activities and Labs
Assessments
Instructional Material
Reference
Student Guide
Teaching and Learning Strategies
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
The College Board The College Board (The College Board;)
Davenport's involvement in the American eugenics movement and Nazism, James WatsonSite: DNA Interactive (www.dnai.org)
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Davenport's involvement in the American eugenics movement and Nazism, James WatsonSite: DNA Interactive (www.dnai.org)

Interviewee: James Watson DNAi Location:Chronicle>In the third reich>taking the torch A common ... (more)

Interviewee: James Watson DNAi Location:Chronicle>In the third reich>taking the torch A common interest Eugen Fischer and Charles Davenport both believed in negative eugenics to prevent those with "bad genes" from reproducing. Taking the torch By the mid-1930s, the scientific basis of negative eugenics had been discredited. The well-documented phenomenon of hybrid vigor refuted notions of racial superiority, while Hardy-Weinberg equilibrium showed that dysgenic genes do not increase in a population. Members of Thomas Hunt Morgan's group showed that the genotype-phenotype relationship is highly variable, while Lionel Penrose found that most cases in a mental institution in Colchester, England resulted from a combination of genetic, environmental, and pathological causes. After a 1935 panel concluded that the work of the Eugenics Record Office was without scientific merit, eugenics research was phased out, and the facility was closed in December 1939. In the meantime, eugenics was gathering steam in Germany ? with help from America. In 1927, the Rockefeller Foundation provided funds for the constructon of the Kaiser Wilhelm Institute of Anthropology, Human Genetics, and Eugenics in Berlin. The director, appropriately named Eugen Fischer, collaborated with Charles Davenport in the management of the International Federation of Eugenics Organizations. On the occasion of the International Eugenics Congress in Rome, in 1929, they drafted a memo to Mussolini encouraging him to move ahead on eugenics with "maximum speed." In 1936, Harry Laughlin's contributions to race hygiene in Germany were recognized with an honorary degree from the University of Heidelberg. Hitler read Fischer's textbook Principles of Human Heredity and Race Hygiene while in prison at Landsberg and used eugenical notions to support the ideal of a pure Aryan society in his manifesto, Mein Kampf (My Struggle). When he came to power in 1933, Hitler charged the medical profession with the task of implementing a national program of race hygiene ? a key element of which was passage of an act permitting involuntary sterilization of feebleminded, mentally ill, epileptics, and alcoholics. Within a year, more than 50,000 sterilizations were ordered, and doctors competed to fill sterilization quotas. By the outbreak of the Second World War in 1939, an estimated 400,000 people had been sterilized. James Watson discusses the founding of the Kaiser Wilhelm Institute for Anthropology, Human Genetics, and Eugenics, the German equivalent of the Eugenics Record Office. (less)

Subject:
History, Law, Politics
Life Science
Social Sciences
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
Eugenics loses favor in the U.S., but gains support in Nazi Germany , James WatsonSite: DNA Interactive (www.dnai.org)
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Eugenics loses favor in the U.S., but gains support in Nazi Germany , James WatsonSite: DNA Interactive (www.dnai.org)

Interviewee: James Watson DNAi Location:Chronicle>In the Third Reich>taking the torch Eugenics lost ... (more)

Interviewee: James Watson DNAi Location:Chronicle>In the Third Reich>taking the torch Eugenics lost favor in the U.S. Hitler and German geneticists were embracing eugenics, even as people in the United States had come to view the movement as mere prejudice. Taking the torch By the mid-1930s, the scientific basis of negative eugenics had been discredited. The well-documented phenomenon of hybrid vigor refuted notions of racial superiority, while Hardy-Weinberg equilibrium showed that dysgenic genes do not increase in a population. 퉌ćMembers of Thomas Hunt Morgan's group showed that the genotype-phenotype relationship is highly variable, while Lionel Penrose found that most cases in a mental institution in Colchester, England resulted from a combination of genetic, environmental, and pathological causes. 퉌ćAfter a 1935 panel concluded that the work of the Eugenics Record Office was without scientific merit, eugenics research was phased out, and the facility was closed in December 1939. In the meantime, eugenics was gathering steam in Germany 퉌_ with help from America. In 1927, the Rockefeller Foundation provided funds for the constructon of the Kaiser Wilhelm Institute of Anthropology, Human Genetics, and Eugenics in Berlin. The director, appropriately named Eugen Fischer, collaborated with Charles Davenport in the management of the International Federation of Eugenics Organizations. On the occasion of the International Eugenics Congress in Rome, in 1929, they drafted a memo to Mussolini encouraging him to move ahead on eugenics with "maximum speed." 퉌ćIn 1936, Harry Laughlin's contributions to race hygiene in Germany were recognized with an honorary degree from the University of Heidelberg. Hitler read Fischer's textbook Principles of Human Heredity and Race Hygiene while in prison at Landsberg and used eugenical notions to support the ideal of a pure Aryan society in his manifesto, Mein Kampf (My Struggle). When he came to power in 1933, Hitler charged the medical profession with the task of implementing a national program of race hygiene 퉌_ a key element of which was passage of an act permitting involuntary sterilization of feebleminded, mentally ill, epileptics, and alcoholics. Within a year, more than 50,000 sterilizations were ordered, and doctors competed to fill sterilization quotas. By the outbreak of the Second World War in 1939, an estimated 400,000 people had been sterilized. James Watson discusses the founding of the Kaiser Wilhelm Institute for Anthropology, Human Genetics, and Eugenics, the German equivalent of the Eugenics Record Office. (less)

Subject:
History, Law, Politics
Life Science
Social Sciences
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
Evolutionary Biology
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Evolutionary Biology

This course will look at the various mechanisms of evolution, how these ... (more)

This course will look at the various mechanisms of evolution, how these mechanisms work, and how change is measured. The course will begin by reviewing the evolutionary concepts of selection and speciation. The student will then learn to measure evolutionary change and look at the history of life according to the fossil record and a discussion of the broad range of life forms as they are currently classified. Upon completion of this course, students will be able to: define evolution and describe different types of selection; provide examples of microevolutionary forces and describe how they impact the genetics of populations; describe the Hardy-Weinberg principle and solve problems related to Hardy-Weinberg equilibrium; provide examples of games used in evolutionary game theory; connect biological phenomena to game theory; develop simple phylogenies from molecular or morphological data; identify important evolutionary events that have occurred throughout geologic time; characterize and provide examples of major plant and animal phyla. (Biology 312) (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Audio Lectures
Full Course
Homework and Assignments
Lecture Notes
Readings
Simulations
Syllabi
Textbooks
Video Lectures
Provider:
The Saylor Foundation
Provider Set:
Saylor Foundation
Measuring Genetic Variability in Natural Populations by Allozyme Electrophoresis
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Measuring Genetic Variability in Natural Populations by Allozyme Electrophoresis

This resource provides detailed descriptions and instructions for running an undergraduate laboratory ... (more)

This resource provides detailed descriptions and instructions for running an undergraduate laboratory exercise focusing on the genetic variability of populations. It includes student and instructor outlines, background information, recommended analyses and sample questions for student laboratory reports. (less)

Subject:
Science and Technology
Chemistry
Life Science
Social Sciences
Education
Material Type:
Activities and Labs
Instructional Material
Lesson Plans
Reference
Student Guide
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Case Western Reserve University
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Association for Biology Laboratory Education (ABLE)
Author:
James M. Bader (Case Western Reserve University;)
Web PopGen
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Web PopGen

A Hardy-Weinberg based population genetics simulator. This program assumes a single gene ... (more)

A Hardy-Weinberg based population genetics simulator. This program assumes a single gene and two alleles. Simulation of allele frequency changes similar to Felsenstein's Simul8 or PopG. Simulates changes in allele frequency based on violations of assumptions of Hardy Weinberg. User may vary starting allele frequency, population size, genotypic fitness, mutation and migration rates and bottleneck population size. Allele frequencies for p and q are graphed for up to 5 populations. When a single population is simulated both allele frequency and genotype frequencies are graphed. (less)

Subject:
Mathematics and Statistics
Science and Technology
Material Type:
Simulations
Provider:
Radford University
Provider Set:
Individual Authors
Author:
Bob Sheehy
The connection between American eugenics and Nazi Germany, James WatsonSite: DNA Interactive (www.dnai.org)
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The connection between American eugenics and Nazi Germany, James WatsonSite: DNA Interactive (www.dnai.org)

Interviewee: James Watson DNAi Location:Chronicle>In the third reich>taking the torch Beginning eugenic ... (more)

Interviewee: James Watson DNAi Location:Chronicle>In the third reich>taking the torch Beginning eugenic sterilization When Hitler came to power in 1933, German eugenicists got the large-scale sterilization program they wanted. Taking the torch By the mid-1930s, the scientific basis of negative eugenics had been discredited. The well-documented phenomenon of hybrid vigor refuted notions of racial superiority, while Hardy-Weinberg equilibrium showed that dysgenic genes do not increase in a population. Members of Thomas Hunt Morgan's group showed that the genotype-phenotype relationship is highly variable, while Lionel Penrose found that most cases in a mental institution in Colchester, England resulted from a combination of genetic, environmental, and pathological causes. After a 1935 panel concluded that the work of the Eugenics Record Office was without scientific merit, eugenics research was phased out, and the facility was closed in December 1939. In the meantime, eugenics was gathering steam in Germany ? with help from America. In 1927, the Rockefeller Foundation provided funds for the constructon of the Kaiser Wilhelm Institute of Anthropology, Human Genetics, and Eugenics in Berlin. The director, appropriately named Eugen Fischer, collaborated with Charles Davenport in the management of the International Federation of Eugenics Organizations. On the occasion of the International Eugenics Congress in Rome, in 1929, they drafted a memo to Mussolini encouraging him to move ahead on eugenics with "maximum speed." In 1936, Harry Laughlin's contributions to race hygiene in Germany were recognized with an honorary degree from the University of Heidelberg. Hitler read Fischer's textbook Principles of Human Heredity and Race Hygiene while in prison at Landsberg and used eugenical notions to support the ideal of a pure Aryan society in his manifesto, Mein Kampf (My Struggle). When he came to power in 1933, Hitler charged the medical profession with the task of implementing a national program of race hygiene ? a key element of which was passage of an act permitting involuntary sterilization of feebleminded, mentally ill, epileptics, and alcoholics. Within a year, more than 50,000 sterilizations were ordered, and doctors competed to fill sterilization quotas. By the outbreak of the Second World War in 1939, an estimated 400,000 people had been sterilized. James Watson discusses the founding of the Kaiser Wilhelm Institute for Anthropology, Human Genetics, and Eugenics, the German equivalent of the Eugenics Record Office. (less)

Subject:
History, Law, Politics
Life Science
Social Sciences
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
A plague outside the Kaiser Wilhelm Institute, James WatsonSite: DNA Interactive (www.dnai.org)
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A plague outside the Kaiser Wilhelm Institute, James WatsonSite: DNA Interactive (www.dnai.org)

Interviewee: James Watson DNAi Location:Chronicle>In the third reich>taking the torch Kaiser Wilhelm ... (more)

Interviewee: James Watson DNAi Location:Chronicle>In the third reich>taking the torch Kaiser Wilhelm Institute The Kaiser Wilhelm Institute of Anthropology, Human Genetics, and Eugenics attempted broad description of human variation and reproduction. Taking the torch By the mid-1930s, the scientific basis of negative eugenics had been discredited. The well-documented phenomenon of hybrid vigor refuted notions of racial superiority, while Hardy-Weinberg equilibrium showed that dysgenic genes do not increase in a population. Members of Thomas Hunt Morgan's group showed that the genotype-phenotype relationship is highly variable, while Lionel Penrose found that most cases in a mental institution in Colchester, England resulted from a combination of genetic, environmental, and pathological causes. After a 1935 panel concluded that the work of the Eugenics Record Office was without scientific merit, eugenics research was phased out, and the facility was closed in December 1939. In the meantime, eugenics was gathering steam in Germany ? with help from America. In 1927, the Rockefeller Foundation provided funds for the constructon of the Kaiser Wilhelm Institute of Anthropology, Human Genetics, and Eugenics in Berlin. The director, appropriately named Eugen Fischer, collaborated with Charles Davenport in the management of the International Federation of Eugenics Organizations. On the occasion of the International Eugenics Congress in Rome, in 1929, they drafted a memo to Mussolini encouraging him to move ahead on eugenics with "maximum speed." In 1936, Harry Laughlin's contributions to race hygiene in Germany were recognized with an honorary degree from the University of Heidelberg. Hitler read Fischer's textbook Principles of Human Heredity and Race Hygiene while in prison at Landsberg and used eugenical notions to support the ideal of a pure Aryan society in his manifesto, Mein Kampf (My Struggle). When he came to power in 1933, Hitler charged the medical profession with the task of implementing a national program of race hygiene ? a key element of which was passage of an act permitting involuntary sterilization of feebleminded, mentally ill, epileptics, and alcoholics. Within a year, more than 50,000 sterilizations were ordered, and doctors competed to fill sterilization quotas. By the outbreak of the Second World War in 1939, an estimated 400,000 people had been sterilized. James Watson discusses the founding of the Kaiser Wilhelm Institute for Anthropology, Human Genetics, and Eugenics, the German equivalent of the Eugenics Record Office. (less)

Subject:
History, Law, Politics
Life Science
Social Sciences
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni ... (more)

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni smelborp gnivlos rof seuqinhcet gnipoleved no si sisahpmE .scipot decnavda detceles dna scihparg retupmoc ,gnihcraes dna gnitros ,serutcurts atad ,sdohtem laciremun ,secafretni resu lacihparg ,stpecnoc gnimmargorp revoc smelborp gnimmargorp ylkeeW .esruoc eht fo sucof eht si tnempoleved dna ngised erawtfos detneiro-tcejbO .snoitacilppa cifitneics dna gnireenigne rof sdohtem lanoitatupmoc dna tnempoleved erawtfos latnemadnuf stneserp esruoc sihT (less)