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Identification of a molecular cause of a neurodevelopmental disorder
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The brain is the most complex biological structure known. All thoughts, movements, and behaviors are coordinated in this control center, where information is processed and transmitted in the form of electrical impulses and chemical signals. It perhaps comes as no surprise then, that alterations in this function can lead to neurological and psychiatric disorders. Now, a new study has pinpointed specific regions of a gene expressed in brain cells that appear to be associated with conditions such as developmental delay and intellectual disability. Neurodevelopmental disorders present early in life and are caused by impairments of growth, development, and function of the brain and central nervous system. With conditions including autism, attention deficit disorder, and schizophrenia, these disorders are characterized by deficits in cognitive, social, or personal functioning..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Genetics
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
02/25/2021
Yeast Transformation and Complementation
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CC BY-NC-SA
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In this module, students use a simple method to transform the budding yeast, Saccharomyces cerevisiae, with yeast expression plasmids containing the GAL1 promoter. At the end of this module, students will be able to:explain the processes of transformation and complmentation at the molecular leveldesign a selection strategy to isolate transformed strains explain how plasmid-encoded genes can complement gene deficienciesuse replica plating on selective media to identify transformed strains expressing plasmid-encoded genesThis module is part of a semester-long introductory laboratory course, Investigations in Molecular Cell Biology, at Boston College. 

Subject:
Biology
Genetics
Material Type:
Module
Author:
Clare OConnor
Date Added:
09/04/2018