This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"More than one-third of people who’ve survived brain hemorrhage stop taking oral anti-blood-clotting drugs, like aspirin. Normally taken to prevent blood vessel blockage, so-called antiplatelet drugs increase the risk of bleeding in general. So they’re widely believed to increase the risk of brain hemorrhage happening again. But new research suggests that might not be the case. Researchers came to that conclusion following a randomized trial involving more than 500 survivors of brain hemorrhage in the UK. Participants were mostly men over the age of 70; all had a history of diseases that cause blockage of blood flow due to clotting but had stopped taking oral antiplatelet drugs after their brain hemorrhage. Researchers split those patients into two groups: half were encouraged to start antiplatelet drugs, and half were encouraged to stay off these drugs..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Students learn about the separation techniques of sedimentation and centrifugation and investigate whether blood is a homogeneous or a heterogeneous mixture. Working in groups as if they are biomedical researchers, they employ the scientific method and make observations about the known characteristics of urine, milk and blood. They probe further by analyzing research on the properties and fractionation modes of blood. As students learn about certain strange characteristics with the fractionation behavior of blood, they formulate hypotheses on the unique nature of blood. Using provided materials —olive oil, tomato juice and petroleum jelly—they design an experiment and construct a blood model. They test their hypotheses by conducting experiments on the blood model, and then propose theories for the nature of blood as a mixture—arriving at the theory of mixture dualism in blood—that blood is a complex mixture system. An activity-guiding handout and PowerPoint® presentation are provided for this student-directed, project-based activity.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Anticoagulation is the cornerstone of therapy for venous thromboembolism, or VTE, in cancer patients, but it may also cause bleeding. Recent studies examining the frequency of these events have primarily focused on the elderly population. A new report in the American Journal of Hematology aimed to take a closer look at the effects of the drugs in younger patients. The work specifically focused on cancer patients who were predominantly under 65 years of age. Researchers evaluated the recurrence of VTE and major bleeding following treatment of a first episode of VTE. Using a retrospective cohort study design, they assessed the outcomes of nearly 14,000 commercially-insured patients initiated on rivaroxaban, warfarin, or low-molecular-weight heparin. Only data from patients with lower extremity deep vein thrombosis and pulmonary embolism were included. Patients were required to have initiated anticoagulation within 7 days of their VTE..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Untreated portal vein thrombosis (PVT) leads to the onset or worsening of portal hypertension Anticoagulation is the mainstay of PVT treatment but its efficacy is not ideal Transjugular intrahepatic portosystemic shunt (TIPSS) can be used for portal vein recanalization after thrombosis This systematic review and meta-analysis evaluated published data on the efficacy and safety of endovascular therapy in PVT The results from 399 patients showed that TIPSS placement was feasible in 95% Major complications occurred in 10%, and additional catheter‐directed thrombolysis was associated with more complications The portal vein recanalization rate was 79% at 12 months The results were limited by a small sample size, largely heterogeneous data and the use of non-controlled, retrospective cohorts This study concluded that TIPSS for PVT recanalization was highly feasible, effective, and safe Randomized trials comparing TIPSS to anticoagulation are therefore needed These future studies will guide c.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.