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The psychedelic compound psilocybin may ‘reset’ the brain to help manage treatment-resistant major depression
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Accumulating evidence suggests that psilocybin – the primary psychedelic compound found in so-called magic mushrooms – can be used to safely treat a range of psychiatric conditions. Prior studies have shown that just one or two doses of psilocybin can have a rapid and lasting positive impact on mental health, but the associated brain mechanisms aren’t well understood. Now, researchers based in the United Kingdom have used functional magnetic resonance imaging to map the brain activity of nineteen patients with treatment-resistant major depression who were given psilocybin. The results shed light on how the compound changes human brain function. The patients were dosed with the drug as part of an open-label clinical trial. Before and one day after treatment, the researchers used fMRI to look at cerebral blood flow and brain functional connectivity – a measure of how different regions of the brain interact..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Anatomy/Physiology
Applied Science
Health, Medicine and Nursing
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019