This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Harmful masses that accompany regular spinal or intrathecal infusions of opiates for pain management might one day be a concern of the past. Researchers have uncovered the cellular mechanisms behind these lesions, which occur with some opioids but not others. Their findings could help improve spinal pain therapy for patients without compromising their health or quality of life. Intrathecal opioids such as morphine are highly effective for managing pain. Direct access to opioid receptors in the spinal cord has made round-the-clock pain management possible, most notably through the use of so-called “pain pumps”. One concern, however, has been the possible formation of collagen-rich masses around the area of drug delivery. These masses, or granulomas, occur in about 8% of patients receiving spinal morphine infusions and have been linked, ironically, to increased pain and reduced neurological function..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"It may be surprising to learn that drugs like morphine can actually make it harder to heal from injuries, including surgery. Researchers report that using opioids to manage this type of acute pain can make the pain last longer, potentially drawing out the need for pain relief. Although it’s unclear exactly why this happens, scientists are beginning to uncover some of the physiological causes of this delayed healing. And they think it has something to do with the brain’s immune system. That conclusion comes from an in-depth look at how morphine affects recovery in mice. Using a mouse model of orthopedic surgery, researchers looked at the consequences of postoperative morphine use. Mice were subjected to tibial fracture and repair and given a 7-day course of either morphine or an inactive vehicle. Some mice underwent a sham operation – they were anesthetized and received skin incisions, but no bone fracture – followed by the same treatment regimen..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan

By the end of this section, you will be able to:Describe the diagnostic criteria for substance use disordersIdentify the neurotransmitter systems affected by various categories of drugsDescribe how different categories of drugs effect behavior and experience

The Maryland State Department of Education is working to prevent the misuse and abuse of opioids. This is a student-centered lesson for 3th grade students. This lesson, Substance Abuse and Making Healthy Choices, can be modified or remixed to meet the needs of the students you teach. The content of this lesson includes explaining by definition what is a drug. Students then learn drugs can come in many forms and can have different uses, and because of this students should not use drugs/medicine unless instructed to by a trusted adult. The content of this lesson is from Anne Arundel County Public Schools.