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A gene co-association network regulating gut microbial communities in Duroc pigs
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The gut microbiota is a diverse ecosystem. While bacteria are present in the greatest numbers, other microorganisms such as fungi and protists are also present, influencing many physiological functions. Analyses of the gut microbiome in livestock species have increased recently with improvements in technology and decreased cost. However, little is known about host genetic control over gut microbial communities. A recent study examined this relationship using healthy Duroc pigs. Using genome-wide association studies, researchers identified a gene regulatory network comprising 3,561 genes and 738,913 connections. Within this complex and polygenic network, five main regulators stood out. The proteins were associated with immune cell development, cell signaling in immune cells, and the vaccine response and a large number of predicted targets were genes associated with microbiota in pigs, mice, and humans. Host genetic variants associated with microbial functions were also identified..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
02/26/2021