Browse Materials (1603)

save
save to

Please log in to save materials.

selected filters:
  • The Human Genome
Bioinformatics, Virtual Labs, and the Human Genome Project

Bioinformatics, Virtual Labs, and the Human Genome Project

This session introduces bioinformatics using a case study of pathogenic bacterial identification ... (more)

This session introduces bioinformatics using a case study of pathogenic bacterial identification via a Howard Hughes Medical Institute's virtual lab and NCBI web database searches. Another goal is to get the students thinking, writing and talking about the impact of the human genome project. Our students do the exercise independently coming together in the laboratory to present and discuss their findings--this feature makes the exercise feasible for large or small classes with limited laboratory computer resources. The sub-theme of this session is the use of virtual laboratories (vlabs) re-enforcing scientific concepts and methods to supplement lectures, tutorials or "wet" labs. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Case Study
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
Howard Hughes Medical Institute|University of Toronto
Author:
Anne L. Cordon
Donna Messersmith
Read the Fine Print
Genomics and Its Impact on Science and Society: The Human Genome Project and Beyond (2008)

Genomics and Its Impact on Science and Society: The Human Genome Project and Beyond (2008)

This site gives a detailed overview of the science of genetics, including ... (more)

This site gives a detailed overview of the science of genetics, including the Human Genome Project. An introduction helps visitors understand genomes, DNA, genes, chromosomes, and more. Other resources include online audio and video files about genetics and the Human Genome Project, images of genomes, current research news, a glossary, frequently asked questions, and a student page. (less)

Subject:
Science and Technology
Material Type:
Readings
Collection:
U.S. Department of Energy
Provider:
Oak Ridge National Laboratory
Read the Fine Print
The Science Scoop: The Human Genome Project

The Science Scoop: The Human Genome Project

This fun Web site is part of OLogy, where kids can collect ... (more)

This fun Web site is part of OLogy, where kids can collect virtual trading cards and create projects with them. Here, they learn about the human genome project by clicking through an online slide show, hosted by kids, that answers these questions: What's a genome, anyway?What is the human genome project? What does it mean to me? (less)

Subject:
Science and Technology
Material Type:
Readings
Collection:
American Museum of Natural History
Provider:
American Museum of Natural History
Read the Fine Print
How Genetic Disorders Are Inherited

How Genetic Disorders Are Inherited

Learn how genetic disorders are passed from parents to children as explained ... (more)

Learn how genetic disorders are passed from parents to children as explained in this excerpt from Blazing a Genetic Trail, from the Howard Hughes Medical Institute. ***Access to Teacher's Domain content now requires free login to PBS Learning Media. (less)

Subject:
Science and Technology
Material Type:
Readings
Collection:
Teachers' Domain
Provider:
PBS Learning Media
Read the Fine Print
Language & Life Sciences: Mapping the Human Genome

Language & Life Sciences: Mapping the Human Genome

Rather than focus on the scientific details of this discovery, this chapter ... (more)

Rather than focus on the scientific details of this discovery, this chapter gives an overview of the important concepts related to DNA's initial discovery and later research conducted in this field. Teachers can use the lesson plans and materials to help students understand these fundamental concepts and gain a command of the vocabulary necessary to discuss them. Given the amazing advances in biological research and the new knowledge that has become available to human beings about their own biological makeup, it is important for students to know basic concepts related to DNA research and the human genome project. This following lesson provides a basic introduction to this topic in an interactive fashion. (less)

Subject:
Science and Technology
Social Sciences
Material Type:
Lesson Plans
Teaching and Learning Strategies
Collection:
U.S. Department of State
Provider:
U.S. Department of State, Bureau of Educational and Cultural Affairs
Author:
Donna M. Brinton, Christine Holten, Jodi L. Nooyen
No Strings Attached
Human Genome Project

Human Genome Project

This video segment from NOVA: "Cracking the Code of Life" looks at ... (more)

This video segment from NOVA: "Cracking the Code of Life" looks at the meaning and significance of the effort to decode the human genome. ***Access to Teacher's Domain content now requires free login to PBS Learning Media. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Collection:
Teachers' Domain
Provider:
PBS Learning Media
Author:
WGBH Educational Foundation
Read the Fine Print
High School Human Genome Project

High School Human Genome Project

The High School Human Genome Program allows high school students to sequence ... (more)

The High School Human Genome Program allows high school students to sequence DNA in their classrooms and to contribute their data to the Human Genome Project. The program was developed jointly by scientists from the University of Washington's Department of Molecular Biotechnology and high school teachers from the Puget Sound region. The goals of the program are to promote a better understanding of DNA research among students by enabling them, under the guidance of their teachers, to sequence portions of the human genome; to stimulate students interest in the ethical, legal and social implications of genome research; and to interest students in careers in science. (less)

Subject:
Science and Technology
Remix and Share
Bioinformatics

Bioinformatics

This exercise contains two interrelated modules that introduce students to modern biological ... (more)

This exercise contains two interrelated modules that introduce students to modern biological techniques in the area of Bioinformatics, which is the application of computer technology to the management of biological information. The need for Bioinformatics has arisen from the recent explosion of publicly available genomic information, such as that resulting from the Human Genome Project. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Collection:
Teaching With Data
Provider:
SERC at Carlton College
Author:
Monica Bruckner
Remix and Share
Genetics

Genetics

Genetics is the branch of biology that studies the means by which ... (more)

Genetics is the branch of biology that studies the means by which traits are passed on from one generation to the next and the causes of similarities and differences between related individuals. In this course, the student will take a close look at chromosomes, DNA, and genes. The student will learn how hereditary information is transferred, how it can change, how it can lead to human disease and be tested to indicate disease, and much more. Upon successful completion of this course, students will be able to: give a brief synopsis of the history of genetics by explaining the fundamental genetic concepts covered in this course as they were discovered through time; identify the links between Mendel's discoveries (often represented by Punnett squares) with mitosis and meiosis, dominance, penetrance, and linkage; recognize the role of simple probability in genetic inheritance; apply advanced genetic concepts, including genetic mapping and transposons, to practical applications, including pedigree analysis and corn kernel color; identify the cause behind several genetic diseases currently prevalent in society (such as color blindness and hemophilia) and recognize the importance of genetic illness throughout history; compare and contrast advanced concepts of chromosomal, bacterial, human, and population genetics; recognize the similarities and differences between nuclear, chloroplast, and mitochondrial DNA; describe the fundamentals of population genetics, calculate gene frequencies in a give scenario, predict future gene frequencies over future generations, and define the role of evolution in gene frequency shift over time; recall, analyze, synthesize, and build on the foundational material to then learn the cutting-edge technological advances in genetics, including genomics, population and evolutionary genetics, and QTL mapping. (Biology 305) (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Audio Lectures
Full Course
Homework and Assignments
Lecture Notes
Readings
Simulations
Syllabi
Video Lectures
Collection:
Saylor Foundation
Provider:
The Saylor Foundation
Read the Fine Print
National Human Genome Research Institute

National Human Genome Research Institute

The National Human Genome Research Institute began as the National Center for ... (more)

The National Human Genome Research Institute began as the National Center for Human Genome Research (NCHGR), which was established in 1989 to carry out the role of the National Institutes of Health (NIH) in the International Human Genome Project (HGP). The HGP was developed in collaboration with the United States Department of Energy (DOE) and begun in 1990 to map the human genome. Now, with the human genome sequence complete since April 2003, scientists around the world have access to a database that greatly facilitates and accelerates the pace of biomedical research. (less)

Subject:
Science and Technology
No Strings Attached
Bioinformatics in the Biology Classroom

Bioinformatics in the Biology Classroom

This educational journal article addresses the implementation of bioinformatics in the classroom. ... (more)

This educational journal article addresses the implementation of bioinformatics in the classroom. The author explains how bioinformatics could play a key role for science students pursuing higher education, foster inquiry learning of content that has often been taught in a dry manner, provide the thread that ties classes together, improve biology teaching, enhance the learning of biotech issues and ethics, expose students to real-world science, and significantly help to reform biology teaching and improve learning. The article includes links to bioinformatics resources, information about how to get involved in bioinformatics, and a glossary of terms. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Collection:
Microbial Life (MLER) (SERC)
Provider:
American Institute of Biological Sciences
Author:
Kathleen M. Gabric
Read the Fine Print
DNA Chips

DNA Chips

In this lesson from Science NetLinks, students will conduct activities from a ... (more)

In this lesson from Science NetLinks, students will conduct activities from a module called "DNA Chips: A Genetics Lab in the Palm of Your Hand." This module is part of the National Institutes of Health Snapshots series, which focuses on a single area of biomedical research to help students understand how science, people, ethics, and history all fit together. The module for this lesson is about the DNA microarray, also known as a DNA chip. (less)

Subject:
Science and Technology
Material Type:
Lesson Plans
Teaching and Learning Strategies
Collection:
Science Netlinks
Provider:
AAAS
Read the Fine Print
DNA Sequencing Used to Illustrate Mutations and Evolution

DNA Sequencing Used to Illustrate Mutations and Evolution

This workshop, which is half wet lab and half Internet lab, uses ... (more)

This workshop, which is half wet lab and half Internet lab, uses DNA sequences to examine the relatedness of different species. DNA from several insect and/or fish species are compared. This chapter includes instructions for extracting DNA from gels and making PCR products. We prepare PCR products to send to a computerized automated sequencing facility. (No radioisotopes are used in this sequencing!) We recover sequence from the facility over the Web as four-color graphics on a computer screen and as text. We make pair-wise DNA sequence comparisons between species with BLAST2 and multi-species comparisons with MultAlin. We see substitutions, insertions, and deletions. Then we make a distance-based evolutionary tree with GeneBee. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
St. Francis College|University of Utah
Author:
Kathleen A. Nolan
Russell LeMon
Theodore Gurney
Read the Fine Print
Incorporating Original Genomics Research into Genetics and Molecular Biology Courses

Incorporating Original Genomics Research into Genetics and Molecular Biology Courses

Genomics and bioinformatics have revolutionized biology over the past few years, but ... (more)

Genomics and bioinformatics have revolutionized biology over the past few years, but their impact on education has lagged. A new revolution is possible in the undergraduate curriculum. We have found novel ways to incorporate genomics research into the laboratory components of several courses. In this chapter, we show how we accomplish the typical skill development goals in a genetics or molecular biology course while accomplishing novel research, and provide the protocols for three such research projects that can be modified to suit the course goals or the instructor's research interests. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
Hiram College
Author:
Brad Goodner
Kathy Wheeler
Read the Fine Print
Genomes and Diversity

Genomes and Diversity

Millions of species of animals, plants and microbes inhabit our planet. Genomics, ... (more)

Millions of species of animals, plants and microbes inhabit our planet. Genomics, the study of all the genes in an organism, is providing new insights into this amazing diversity of life on Earth. We begin with the fundamentals of DNA, genes and genomes. We then explore microbial diversity, with an emphasis on how genomics can reveal many aspects of organisms, from their ancient history to their physiological and ecological habits. We follow with examinations of animal and plant diversity, focusing on domesticated species, such as dogs and tomatoes, as examples of how genomic methods can be used to identify genes that underlie new or otherwise interesting traits. Genomics has also transformed the study of human diversity and human disease. We examine the use of DNA to trace human ancestry, as well as the use of genomics as a diagnostic tool in medicine. With the powerful new technologies to study genomes has come an increased power to manipulate them. We conclude by considering the societal implications of this ability to alter the genomes of crop plants, livestock and potentially humans. (less)

Subject:
Science and Technology
Material Type:
Video Lectures
Collection:
New York University
Provider:
New York University
Author:
Mark L. Siegal
Read the Fine Print
An Introduction to Bioinformatics

An Introduction to Bioinformatics

This HIBBs presentation provides background information on bases, amino acids, proteins, nucleotides, ... (more)

This HIBBs presentation provides background information on bases, amino acids, proteins, nucleotides, and DNA. The presentation then explains what bioinformatics is, lists some examples, and demonstrates some tools. It demonstrates tools which compare parts of human and chimp genes, and illustrates drug resistance analysis and HIV subtype analysis. It then discusses some ethical and clinical aspects to bioinformatics. (less)

Subject:
Science and Technology
Material Type:
Assessments
Images and Illustrations
Lesson Plans
Unit of Study
Video Lectures
Collection:
African Health OER Network
Provider:
Global Health Informatics Partnership
Author:
Yashik Singh
Remix and Share
Genetic Education Modules for Teachers

Genetic Education Modules for Teachers

These teaching modules include specific teaching plans to present the history, facts ... (more)

These teaching modules include specific teaching plans to present the history, facts and genetic terminology behind the Human Genome Project, and the ethical, legal and social questions surrounding the discoveries and advancements of this research. (National Human Genome Research Institute) (less)

Subject:
Science and Technology
Social Sciences
Material Type:
Lesson Plans
Readings
Collection:
National Institutes of Health
Provider:
National Institutes of Health
No Strings Attached
Using DNA to Identify People

Using DNA to Identify People

it would be ideal if students already have learned that DNA is ... (more)

it would be ideal if students already have learned that DNA is the genetic material, and that DNA is made up of As, Ts, Gs, and Cs. It also would help if students already know that each human has two versions of every piece of DNA in their genome, one from mom and one from dad. The lesson will take about one class period, with roughly 30 minutes of footage and 30 minutes of activities. (less)

Subject:
Science and Technology
Material Type:
Video Lectures
Collection:
MIT Blossoms
Provider:
MIT, Learning International Networks Consortium
Author:
Megan E. Rokop
Remix and Share
Genetic Origins

Genetic Origins

The goal of the Genetic Origins Program is to allow students to ... (more)

The goal of the Genetic Origins Program is to allow students to use their own DNA variations (polymorphisms) as a means to explore our shared genetic heritage and its implications for human health and society. Genetic Origins focuses on two types of DNA variations: an Alu insertion polymorphism on chromosome 16 (PV92) and single nucleotide polymorphisms (SNPs) in the control region of the mitochondrial (mt) chromosome. With two alleles and three genotypes, PV92 is a simple genetic system that illustrates Mendelian inheritance on a molecular level. PV92 data is readily analyzed using population statistics. The mt control region is one of the simplest regions of human DNA to sequence. With a high mutation rate, the mt control region is the "classical" system for studying human and primate evolution. The Genetic Origins site and linked Bioservers site have all the information needed for students to perform the Alu and mt DNA experiments and analyze the results - including online protocols, reagents, animations and videos explaining key concepts, and database tools. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Simulations
Collection:
Dolan DNA Learning Center
Provider:
Cold Springs Harbor
Read the Fine Print
2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni ... (more)

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni smelborp gnivlos rof seuqinhcet gnipoleved no si sisahpmE .scipot decnavda detceles dna scihparg retupmoc ,gnihcraes dna gnitros ,serutcurts atad ,sdohtem laciremun ,secafretni resu lacihparg ,stpecnoc gnimmargorp revoc smelborp gnimmargorp ylkeeW .esruoc eht fo sucof eht si tnempoleved dna ngised erawtfos detneiro-tcejbO .snoitacilppa cifitneics dna gnireenigne rof sdohtem lanoitatupmoc dna tnempoleved erawtfos latnemadnuf stneserp esruoc sihT (less)

Subject:
Science and Technology
Material Type:
Assessments
Full Course
Homework and Assignments
Lecture Notes
Syllabi
Collection:
MIT OpenCourseWare
Provider:
M.I.T.
Author:
George Kocur
Remix and Share