In this lesson, you will examine how popular music reflects the diverse attitudes of the American people at different times throughout history.  Through hands-on activities, you will learn how music can empower people to fight for a common cause. You will discover how protest songs evolved throughout history. For the culminating activity, you will create an annotated playlist of your top ten protest songs of all time.StandardsCC.8.5.9-10.D: Determine the meaning of words and phrases as they are used in a text, including vocabulary describing political, social, or economic aspects of history/social science.

This webinar will focus on practical applications of the FAIR data principles, particularly in the context of clinical bioinformatics. We will highlight several example projects that have put the FAIR principles in practice, and discuss the advantages and some of the challenges involved. ELIXIR Galaxy community (elixir-europe.org/communities/galaxy) promotes the use of Galaxy projects that enhance the FAIRness in data analysis. We will demonstrate the Galaxy services that deliver practical FAIR data analysis with “Single Sign-On” capability provided by ELIXIR-AAI. The aim is to provide (medical) researchers with the practicalities of implementing and using FAIR principles in the context of the CINECA project as applied to translational research at Erasmus University Medical Center.

The “How FAIR are you” webinar series and hackathon aim at increasing and facilitating the uptake of FAIR approaches into software, training materials and cohort data, to facilitate responsible and ethical data and resource sharing and implementation of federated applications for data analysis.

Who is this course for?
Researchers, especially those working in clinical bioinformatics, with an interest in applying FAIR principles to data analysis.

This self-paced course was originally designed to help prepare incoming MIT students for their first Introductory Biology Course (known at MIT as 7.01). It will also be useful for anyone preparing to take an equivalent college-level introductory biology class elsewhere. It includes lecture videos, interactive exercises, problem sets, and one exam.  Lecture Topics: Molecules of Life, The Cell and How it Works, Information Transfer in Biology, Inheritance and Genetics, and Building with DNA.
Go to OCW’s Open Learning Library site for Pre-7.01: Getting up to Speed in Biology. The site is free to use, just like all OCW sites. You have the option to sign up and enroll in the course if you want to track your progress, or you can view and use all the materials without enrolling.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death worldwide. Despite advancements in HCC diagnosis and treatment, current staging systems lack specificity and can’t easily predict patient survival. Researchers now report a new prognostic and diagnostic approach based on tracking genes that control iron metabolism in the body. Iron is critical for normal cell metabolism, growth, and proliferation. That goes extra for tumor cells, which have an increased demand for iron. But too much iron can lead to cell death—a process known as “ferroptosis”—which some researchers are harnessing to eliminate harmful cancer cells. In the current study, researchers used high-throughput sequencing to identify genes associated with iron metabolism and ferroptosis in patients with HCC. Based on four genes, patients could be divided into a low-risk group and a high-risk group with poorer overall survival and HCC samples could be distinguished from normal samples..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Joint webinar with ASAPbio, Sumeet Pal Singh and Europe PMC

Preprints enable researchers to rapidly share their work publicly before the formal peer review process. In this webinar you will learn more about preprints and their benefits for the research community from ASAPbio (Accelerating Science and Publication in biology); will hear an author’s perspective on posting preprints from Sumeet Pal Singh, a group leader at IRIBHM, ULB; and will find out how to incorporate preprints in your literature search routine by using the preprint discovery tools developed by Europe PMC.

ASAPbio is a scientist-driven nonprofit that promotes the productive use of preprints in the life sciences. ASAPbio coordinates a global community of researchers and stakeholders interested in preprints and develops resources to advance best practices and help researchers make informed decisions about communicating their work via preprints. Iratxe Puebla, Associate Director at ASAPbio, will provide an overview of preprints and their growth in the life sciences, and cover things researchers should consider before posting a preprint.

Sumeet Pal Singh is a group leader at IRIBHM, ULB and an ASAPbio fellow. Sumeet will describe the journey of publishing his first senior author paper from a preprint to a peer-reviewed article, as well as the details related to the timing of posting a preprint and its relationship to the peer-review process. He will outline a new path provided by Review Commons that allows the authors to receive peer reviews for their manuscript prior to a journal submission, as well as post the reviewer’s comments and the authors’ response on preprint server (bioRxiv).

Europe PMC indexes over 300,000 preprints abstracts and full text COVID-19 preprints from 20 life sciences preprint servers alongside published journal articles. Preprints in Europe PMC are linked to citations, data, community peer reviews and more. In this part of the talk we will demonstrate how to find relevant preprints, cite and track preprint citations, claim preprints to ORCID, or discover relevant resources.

Who is this course for?
This webinar is suitable to any biological researchers who wish to learn more about incorporating preprints into their research. No prior knowledge is required.

Outcomes
By the end of the webinar you will be able to:

Define what a preprint is
Choose a suitable preprint server for your work
Maximise the options for publication of the preprint at a journal
Decide when to post your manuscript as a preprint
Deal with community reviews and comments
Identify how to search for relevant preprints
Find data behind the preprint
Find comments or reviews associated with a preprint
Add a preprint publication to your publication list
Cite a preprint

Preprints enable researchers to rapidly share their work publicly before the formal peer review process. This webinar will demonstrate how to incorporate preprints in your literature search routine by using the discovery tools developed by Europe PMC.

Europe PMC indexes preprints abstracts and full text COVID-19 preprints from many life sciences preprint servers alongside published articles. Preprints in Europe PMC are linked to data and platforms that comment on or peer review preprints. We will demonstrate how to find the data behind preprints as well as comments and reviews associated with a given preprint. We will also share useful tips for posting your pre-prints, claiming a pre-print to your ORCID and tracking your pre-prints’ citations, revisions or recommendations by readers.

To learn more about using Europe PMC in your research try our Europe PMC: Quick tour or our webinar Using Europe PMC for effective literature research.

Who is this course for?
This webinar is suitable to any biological researchers who wish to learn more about incorporating pre-prints into their research. No prior knowledge is required.

Outcomes
By the end of the webinar you will be able to:

Define what a preprint is
Identify how to search for relevant preprints
Find data behind the preprint
Find comments or reviews associated with a preprint
Demonstrate how to add a preprint publication to your publication list
Describe how to cite a preprint

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"In recent years, the study of microbial communities has greatly benefitted from advances in both genetic sequencing and more traditional culture-based approaches, unlocking their potential to drive the development of new medical treatments like never before, but the techniques used for sample preservation could affect which microbes are ultimately cultured and thus constrain the discovery of previously undescribed species and microbial functions. To better understand how preservation affects the study of anaerobic bacteria in the gut, researchers froze human fecal samples at -80°C after adding Cary-Blair medium with or without 20% glycerol or 5% dimethyl sulfoxide (DMSO) to some of them. These preservatives are often used when transporting and freezing fecal and other clinical specimens. They found that the preservation conditions affected the number of bacterial anaerobes cultured from the samples, as well as the recovery of particular genera..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Our gut microbiomes are rich communities of bacteria, archaea, and viruses that play critical roles in our health. But although bacteria and archaea in the gut are well-characterized, the gut virome is less understood. A recent study sought to better understand a specific component of the gut virome. Double-stranded DNA bacteriophages (dsDNA phages) – viruses that infect bacteria – play pivotal roles in structuring the human gut microbiome. Using a new multilevel framework for taxonomic classification of viruses, researchers searched human gut metagenomes for phage hallmark genes. They identified 3,738 apparently complete phage genomes, representing 451 putative genera. Several of the genera were new, only distantly related to previously identified phages. Two of the candidate families – “Flandersviridae” and “Quimbyviridae” – included common members of the gut virome that infect ubiquitous gut bacteria, while the third family, “Gratiaviridae,” comprised less abundant phages..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

In the video you can find some hints to design a primers for clone your GOI in a plasmid using restriction enzyme and ligase cloning approach

Short Description:
Now available in print at Amazon.com and via the OSU Press! Data Dashboard

Long Description:
A Primer for Computational Biology aims to provide life scientists and students the skills necessary for research in a data-rich world. The text covers accessing and using remote servers via the command-line, writing programs and pipelines for data analysis, and provides useful vocabulary for interdisciplinary work. The book is broken into three parts: Introduction to Unix/Linux: The command-line is the “natural environment” of scientific computing, and this part covers a wide range of topics, including logging in, working with files and directories, installing programs and writing scripts, and the powerful “pipe” operator for file and data manipulation. Programming in Python: Python is both a premier language for learning and a common choice in scientific software development. This part covers the basic concepts in programming (data types, if-statements and loops, functions) via examples of DNA-sequence analysis. This part also covers more complex subjects in software development such as objects and classes, modules, and APIs. Programming in R: The R language specializes in statistical data analysis, and is also quite useful for visualizing large datasets. This third part covers the basics of R as a programming language (data types, if-statements, functions, loops and when to use them) as well as techniques for large-scale, multi-test analyses. Other topics include S3 classes and data visualization with ggplot2.

Word Count: 111597

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

A Primer of Evolution is an open educational resource designed for upper-level college students. It provides a succinct introduction to evolutionary thought revolving around theory, evidence, and practice:
- It introduces some of the theoretical cornerstones and core concepts of modern evolutionary biology. The goal is for students to be able to apply these concepts and articulate testable hypotheses that explain natural phenomena from an evolutionary perspective.
- It highlights the diversity of empirical approaches and lines of evidence that scientists use to address evolutionary hypotheses.
- It helps students to practice approaching problems like scientists and evaluate data to address evolutionary hypotheses. To do so, students learn how to program in R to analyze and visualize data and articulate your interpretations and conclusions.

Each chapter provides a conceptual introduction to the topic and includes R-based exercises that allow students to visualize relevant datasets to practice the testing of evolutionary hypotheses. To help with the R exercises, each chapter also provides additional background on case studies and R programming tutorials that help students to develop the necessary skills.

Chapters:
What Evolution Is
Evidence for Evolution
A Mechanism for Change
The Raw Materials for Evolution
Evolutionary Mechanisms I: Modeling Selection
Evolutionary Mechanisms II: Mutation, Genetic Drift, Migration, and Non-Random Mating
Evolution of DNA Sequences
Evolution of Quantitative Traits
Adaptation and Phenotypic Plasticity
Social Behavior and Sexual Selection
Speciation
Evolutionary Medicine I: Aging and Diseases of Civilizations
Evolutionary Medicine II: Evolving Pathogens
Human Evolution

In this video segment from NatureScene, observe dragonflies and mayflies near Cedar Creek at Congaree Swamp National Park.

Principals of Biology: Identifying Organisms Using A Key, And Introduction To Phylogenies

BI 212
Principles of Biology
Description

Includes inheritance, the genetic code, modern and classical genetics, evolution, diversity, and systematics. May include some dissection of plants and animals. The second course in a three-course sequence for students majoring in biology and the sciences, including pre-medical, pre-dental, chiropractic, pharmacy, and related fields

This course helps in developing skills as science communicators through projects and analysis of theoretical principles. Case studies explore the emergence of popular science communication over the past two centuries and consider the relationships among authors, audiences and media. Project topics are identified early in the term and students work with MIT Museum staff. Projects may include physical exhibits, practical demonstrations, or scripts for public programs.

Biology 211, 212, and 213

Short Description:
The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Long Description:
The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research. BI211 focuses on how structure defines function in organisms and the pathways and transformation of energy in living systems. BI212 uses genetics as a model system to understand information flow in living organisms. BI213 focuses on the interactions of living systems and the ecology and evolution of biodiversity.

Word Count: 194123

ISBN: 978-1-63635-040-0

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

This textbook is designed specifically for Kansas State's Biology 198 Class. The course is taught using the studio approach and based on active learning. The studio manual contains all of the learning objectives for each class period and is the record of all student activities. Hence, this textbook is more of a reference tool while the studio manual is the learning tool.

This course provides an introduction to the chemistry of biological, inorganic, and organic molecules. The emphasis is on basic principles of atomic and molecular electronic structure, thermodynamics, acid-base and redox equilibria, chemical kinetics, and catalysis. One year of high school chemistry is the expected background for this freshman-level course.
The aims include developing a unified and intuitive view of how electronic structure controls the three-dimensional shape of molecules, the physical and chemical properties of molecules in gases, liquids and solids, and ultimately the assembly of macromolecules as in polymers and DNA. Relationships between chemistry and other fundamental sciences such as biology and physics are emphasized, as are the relationships between the science of chemistry to its applications in environmental science, atmospheric chemistry and electronic devices. 

Acknowledgements
Professor Drennan would like to acknowledge the contributions of MIT Lecturer Dr. Elizabeth Vogel Taylor, Professor Sylvia Ceyer, and Professor Robert Silbey to the development of this course and its materials.

This course presents the principles of evolution, ecology, and behavior for students beginning their study of biology and of the environment. It discusses major ideas and results in a manner accessible to all Yale College undergraduates. Recent advances have energized these fields with results that have implications well beyond their boundaries: ideas, mechanisms, and processes that should form part of the toolkit of all biologists and educated citizens.

Designed to meet the scope and sequence of your course, Principles of Finance provides a strong foundation in financial applications using an innovative use-case approach to explore their role in business decision-making. An array of financial calculator and downloadable Microsoft Excel data exercises also engage students in experiential learning throughout. With flexible integration of technical instruction and data, this title prepares students for current practice and continual evolution.

This course covers current understanding of, and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Topics include: The Genetics of Simple and Complex Traits; Karyotypic Analysis and Positional Cloning; Genetic Diagnosis; The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression, and Treatment; The Interaction between Genetics and Environment; Animal Models of Human Disease; Cancer; and Conventional and Gene Therapy Treatment Strategies.