This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Gene regulation plays a critical role in human development and disease, including cancer. Genes are regulated by a family of proteins called transcription factors. One such molecule is GLI3, a member of the "Hedgehog" signaling pathway. GLI3 can switch genes ON (such as in development and cancer) and switches gene expression OFF in Hedgehog signaling. This central molecule is important for tissue development in the brain and lungs and for the development and activation of immune cells such as B, T and NK cells. GLI3 is upregulated in many cancers, promoting growth, angiogenesis, and tumor cell proliferation and migration, but interestingly, in certain cancers, GLI3 has an anti-tumor role. and its pro-cancerous role can be modulated by GLI3-targeting microRNA. Understanding GLI3-mediated signaling will clarify its roles in disease, development, and cancer, laying the foundation to target this critical molecule in immune and cancer therapies..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

What factors lead to a natural disaster? What causes a famine? Why do cities flood? According to a recent article in The Atlantic, Houston's flooding during the 2017 Hurricane Harvey was primarily caused by impervious pavement which prevents the absorption of water into the land. This example illustrates how nature and society are interlinked, which is the main focus of Geography 30, Penn State's introductory course to nature-society geography. In addition to examining the linkages between human development and natural hazards, this course will also explore human society's connection to food systems, climate change, urbanization and biodiversity. The course will also cover topics of ethics and decision making in order to help students evaluate the tradeoffs of these interconnections.
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In this activity, students explore the relationship between developmental biology and macroevolution by focusing on how evolutionary changes in ontogeny can produce small-scale (within species) and large-scale (between species or major lineages) evolution of morphology.

In Part A, students begin the activity by measuring skull length vs. braincase width in an ontogenetic sequence of an "ancestral" wolf species. They graph the resulting data then determine whether the relationship between the two is isometric or allometric.

In part B, they choose three skulls of adult domestic dog breeds (available via online sources such as Skulls Unlimited). Measure the same two variables and compare these "descendent" data to the wolf "ancestral" data. In this way, they determine which dog breeds (e.g., pugs, bulldogs) appear to be paedomorphic and which (e.g., greyhounds) appear to be peramorphic.

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This eight-week module focuses on a “science and society” topic, engaging students in reading compelling informational text about adolescent brain development and the effects of entertainment screen time on the brain.

In Unit 1, students first read various texts that will build their background knowledge about adolescent brain development in general. Their learning will center around three areas of the brain, namely the prefrontal cortex, the limbic system, and the developing neurons. Students determine main ideas and evidence in diverse media and clarify their learning about this complex content. Then they begin to focus on the issue of screen time and how it may affect teenagers.

Find the rest of the EngageNY ELA resources at https://archive.org/details/engageny-ela-archive .

Course Overview:
This course covers the basic statistical principles, procedures, and interpretations of statistical analyses in the behavioral sciences in order to provide an understanding of what is involved in analyzing quantitative data. The course will offer introductory coverage of descriptive and inferential statistics through the use of RStudio. Course topics include data description, central tendency and variability, statistical inference, and significance tests to compare means and conduct analyses of correlation and regression.

Student Learning Objectives:
Through the successful completion of this course, students will:
1) Develop knowledge and critical understanding of fundamental issues related to methodology and the application of various statistical tools.
2) Develop basic skills in using RStudio for data entry, data management, and data analysis.
3) Learn to appropriately interpret the output of statistical software and analyses and to communicate effectively with others regarding results and conclusions.
4) Be able to identify key information in published quantitative research manuscripts.
5) Be prepared to take more advanced statistics courses, such as analysis of variance and multiple regression models.

UCSD Cognitive scientist Joan Stiles reveals the latest understandings about the intricate relationship between biology and external influences in the development of the brain. (58 minutes)

In this edition of "Grey Matters," Aniruddh Patel, of the Neurosciences Institute, discusses what music can teach us about the brain, and what brain science, in turn, can reveal about music. (51 minutes)

Is sleep for rest? To conserve energy? For development? To cool the brain? To warm it? To boost the immune system? To learn and memorize? Or to unlearn, ridding our brains of excess mental baggage? All of these ideas have been proposed, leading to the suggestion that insomniacs might do better to count sleep theories instead of sheep. Join renowned neuroscientist Ralph Greenspan of The Neurosciences Institute to explore the latest research into the question of why we sleep. (59 minutes)

During the past decade, there have been dramatic advancements in the brain and cognitive sciences. For the first time, understanding how the brain works has become a scientifically achievable goal. In this new lecture series, Grey Matters: Molecules to Mind, San Diego's leading Neuroscientists explore the human brain. The first lecture in this series addresses an issue that has often been absent in these discussions: what role do stem cells play in development of the brain? (59 minutes)

UCSD cognitive scientist Martin Sereno takes you on a captivating exploration of the brain's structure and function as revealed through investigations with new advanced imaging techniques and understandings of evolution. (57 minutes)

Why are humans the only species to have language? Is there something special about our brains? Are there genes that have evolved for language? In this talk, Jeff Elman, UCSD professor of cognitive science and co-director of the Kavli Institute for Brain and Mind, discusses some of the exciting new research that helps us understand what it is about human language that is so different from other animals' communication systems, and what about our biology might make language possible. (58 minutes)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"For scientists and other academics hoping to translate their findings into political change, policy experts offer the following advice: Tell a good story. Unfortunately, the academic literature—researchers’ go-to source for evidence that things actually work the way people claim they do—says little on how to go about crafting a compelling narrative. For that, says media expert Brett Davidson, researchers must delve into a lesser known but no less copious store of useful know-how: the grey literature. In a recent paper, Davidson outlines how this overlooked body of work provides researchers a manual for landing on the political agenda. A catch-all term for any research or materials not controlled by commercial publishers, the grey literature is a compendium of lessons learned through trial and error. Long a survival guide for policy advocates and activists working in the non-profit world, now, Davidson argues, it’s time for researchers to take advantage, too..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This collection of six images captures the magnificence of human development -- the transformation from baby to woman.

HDFS 414

Short Description:
Strategies for, and roles of professional specialists in, the solution of problems in human development and family functioning.

Word Count: 16397

Included H5P activities: 24

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Small metabolites produced by gut microbes can directly affect the central nervous system, but it’s unclear if these molecules influence very early stages of neural development. To find out, researchers recently compared normal and germ-free zebrafish embryos. There were no gross morphological differences, but neural gene expression was significantly suppressed in the germ-free embryos and this suppression was eliminated by treatment with zebrafish gut metabolites. Specifically, 354 genes were downregulated in germ-free compared with normal embryos and just a single treatment with zebrafish gut metabolites restored the normal expression levels of 39 of these genes. The downregulated genes were involved in important neurodevelopmental pathways, such as transcriptional regulation and Wnt signalling and closer investigation at the cellular level confirmed that Wnt-dependent developmental features were disrupted in the germ-free embryos..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This is a lesson dealing with a new subdivision of bioethics called neuroethics. As our knowledge of the brain and nervous system expands, so do the ethical issues that result from this knowledge. This new area of study results from our increasing research in the field of neurobiology. In the first part of this activity, students will discuss the stigma associated with psychological illness. They will then be introduced to Dr. Kay Jamison who discusses some of the ethical implications of bipolar disorder. The class will take part in an activity called a Topical Barometer where they will have to choose a position regarding an ethical decision. In Part 2 of the activity, they will write a position paper after exploring the topic of drug enhancement, another controversial issue in the world of neuroscience. From the original handout text by Caren Gough

Students learn about the anatomy of the ear and how the ears work as a sound sensor. Ear anatomy parts and structures are explained in detail, as well as how sound is transmitted mechanically and then electrically through them to the brain. Students use LEGO® robots with sound sensors to measure sound intensities, learning how the NXT brick (computer) converts the intensity of sound measured by the sensor input into a number that transmits to a screen. They build on their experiences from the previous activities and establish a rich understanding of the sound sensor and its relationship to the TaskBot's computer.

This course explores recent historical and anthropological approaches to the study of medicine and biology. Topics might include interaction of disease and society; science, colonialism, and international health; impact of new technologies on medicine and the life sciences; neuroscience and psychiatry; race, biology and medicine. Specific emphasis varies from year to year.

This lesson highlights the similarities between human sensors and their engineering counterparts. Taking this approach enables students to view the human body as a system, that is, from the perspective of an engineer. Humans have recreated most human sensors in robots – eyes, ears and sensors for temperature, touch and smell. The lesson inculdes a PowerPoint file that is programmed to run a Jeopardy-style game as a fun assessment tool.

Students learn more about how light sensors work, reinforcing their similarities to the human sense of sight. They look at the light sensing process incoming light converted to electrical signals sent to the brain through the human eye anatomy as well as human-made electrical light sensors. A mini-activity, which uses LEGO MINDSTORMS(TM) NXT intelligent bricks and light sensors gives students a chance to investigate how light sensors function in preparation for the associated activity involving the light sensors and taskbots. A PowerPoint® presentation explains stimulus-to-response pathways, sensor fundamentals, and details about the LEGO light sensor, including its two modes of gathering data and what its numerical value readings mean. Students take pre/post quizzes and watch a short online video. This lesson and its associated activity enable students to gain a deeper understanding of how robots can take sensor input and use it to make decisions via programming.