This case study uses a PowerPoint (~1MB) combined with role-playing to present the epidemiology and pathophysiology of Severe Acute Respiratory Syndrome (SARS). Students learn about the etiology and pathophysiology of the disease, and then argue different health professionals' perspectives on a plan of action for dealing with its consequences. Developed for a pathophysiology course for undergraduates, the case could also be used in a microbiology course or in a course in public or international health.
As the carbon dioxide concentration of our atmosphere increases and our climate warms, the hay fever season seems to be getting longer and more severe. In this case study, students assume the a role of a public relations specialist contracted to communicate the link between climate change and pollen allergies. The activity focuses on the importance of scientific skills to careers outside science, and is most suitable for a lower-level introductory biology, human health, or environmental science course.
This case introduces students to HIV, its life cycle, treatment, and problems associated with treatment options. The case, which incorporates critical thinking skills, active learning, self-directed study, and peer-to-peer learning, was developed for use in an undergraduate upper-level biology course entitled "The Molecular Basis of Disease." It could also be used in an immunology class, a molecular evolution class, or a general biology class to introduce viruses.
In this decision case, a congressional staffer must weigh a number of competing concerns and issues, including popular reactions to genetically modified organisms, in deciding how to present information to her boss, an influential congressman drafting legislation to support agricultural research. The case explores the social and biological issues surrounding micronutrient malnutrition, including deficiencies of several vitamins and essential minerals, especially iron, iodine, and vitamin A, which affect at least one-third of the world's population, primarily in developing nations. Developed for a graduate-level seminar on "Genomics, Agriculture, Food Systems and Development," the case teaches about the issues surrounding genomic applications in agriculture and their implications to health, environmental stewardship, economic sustainability, and national development.
This case study presents a fictitious bio-terrorist plan to release anthrax in the United States. Students are assigned character roles and, through research, role-playing, and teamwork, develop a plan to minimize or avert the attack. The case is appropriate for courses designed for health professionals, general biology courses, and social science courses.
Much of the more than 30 million tons of asbestos used in the United States since 1900 is still present as insulation in offices and schools, as vinyl-asbestos flooring in homes, and in other common products. This book presents a comprehensive evaluation of the relation of these fibers to specific diseases and the extent of non-occupational risks associated with them. It covers sources of asbestiform fibers, properties of the fibers, and carcinogenic and fibrogenic risks they pose. The book may be read online, printed, or purchased from the site.
The ethics of human experimentation are explored in this case about the infamous syphilis studies performed at the Tuskegee Institute from the 1930s to the 1960s. Sponosred by the U.S. Public Health Service, 399 African American men with syphilis were recruited for a research study on the progression of the disease when left untreated. The case examines the science underlying the experiment as well as the ethical and racial issues. One of its goals is to help students understand the evolution in our thinking on issues of science, human experimentation, and race, and how they are conditioned by our culture. The case could be used in any course that explores the ethics of science.
Many difficult ethical questions have arisen from the explosive growth of biomedical research and the health-care industry since World War II. When and how should doctors be allowed to help patients end their lives? Should embryos be cloned for research and/or reproduction? Should parents be given control over the genetic make-up of their children? What sorts of living things is it appropriate to use as research subjects? How should we distribute scarce and expensive medical resources? While some of these questions are genuinely new, products of rapid changes in biomedical technology, others have been debated for centuries. Drawing on philosophy, history, and anthropology, this course will show students how problems in bioethics can be approached from a variety of perspectives, with the aim of understanding how we have gotten where we are, and how we should decide where to go next.
" This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) — what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers."
In the weeks following the September 11, 2001, terrorist attacks on the World Trade Center and the Pentagon, anthrax-laced envelopes were mailed to individuals in government and the news media. Thousands were treated for exposure, and five people were killed. At the same time, scientists solved the last remaining pieces of the anthrax puzzle and the mechanism of infection of the anthrax toxin is now well understood. Developed for a second-semester biochemistry course, this case presents students with a wealth of biochemical, microbiological, and immunological material to analyze. It also explores important societal issues related to national preparedness against bioterrorist attacks, funding for biodefense research, and the use and misuse of antibiotic therapy.
In this course, we will seek to interpret capitalism using ideas from biological evolution: firms pursuing varied strategies and facing extinction when those strategies fail are analogous to organisms struggling for survival in nature. For this reason, it is less concerned with ultimate judgment of capitalism than with the ways it can be shaped to fit our more specific objectives – for the natural environment, public health, alleviation of poverty, and development of human potential in every child. Each book we read will be explicitly or implicitly an argument about good and bad consequences of capitalism.
The objective of this presentation is to use three illustrative case studies to reinforce basic concepts and principles of terrorism preparedness and response, as well as to identify some specific practical considerations. These case studies will illustrate: (1) Plausible scenarios, (2) Typical first response activities, (3) Critical issues on-the-fly, and (4) Considerations for planning.
This interrupted case study presents a discussion about the benefits of the influenza vaccine between Mary, a nursing student, and her coworker, Karen. Karen is not convinced by Mary's arguments in favor of vaccination, and she counters with several common rationalizations for not getting the vaccine. Students work in small groups to evaluate the arguments for and against vaccination from the perspective of each woman. In addressing the questions in the case, students learn about the general biology of viral infections, treatment of infections, and immunity. The case was designed for use in an entry-level course in microbiology for nursing students or a first-year biology course for majors.
This case study highlights the epidemiological and socioeconomic factors associated with a disease which plagues thousands of people in Central and South America. The case follows the story of Adrian, a banana plantation worker in southwestern Costa Rica who develops a mysterious illness. Students learn about infectious diseases, pathogens, and vectors endemic to the region, and are asked to diagnose Adrian's illness and consider his dilemma with respect to treatment options. The case is appropriate for courses with a component on health care, pharmacology, microbiology, medical anthropology, ethnobotany, or epidemiology. Instructors can choose to focus more on the biological components of the case or more on the socioeconomic and ethical aspects, depending on course goals and subject area.
Three newborns left in the care of Dr. Matthew Mitchell have developed a mysterious rash. Under increasing pressure from hospital administrators and distressed parents, Dr. Mitchell must diagnose and treat the infants. Students are given discrete pieces of information in this interrupted case study and asked to find additional information outside of class to solve the mystery. The case was developed for use in a clinically oriented microbiology course for nursing, allied health, and pre-medical students.
In this case study, students analyze a scientific study, first by analyzing news articles reporting on the research and then by reading the original research article. In working through the case, students identify the basic elements of a scientific study; evaluate the study and offer suggestions for improvement; analyze the appropriateness of the headlines of news articles in relation to their content; and compare the accuracy of information offered to the public in a news article with the information presented in a scientific paper. Designed for an introductory course in biological sciences for non-majors, the case could be used in any course that includes the study of the scientific method as well as in a scientific journalism course.
This case describes the pioneering work of Ignaz Semmelweis and his efforts to remedy the problem of childbed fever in mid-19th century Europe. Its purpose is to teach students about the scientific method by "dissecting" the various steps involved in this important, historical medical breakthrough. The case is an interrupted case, that is, students receive only one piece of information at a time, followed by discussion, before moving on to the next piece of information to solve the mystery.
This interrupted case study focuses on the research of Dr. Beatrice Hahn, who investigates DNA sequences in chimpanzee droppings in order to explore the origins of the human immunodeficiency virus (HIV). Students first consider the types of data that can be gained through collecting chimpanzee feces and studying the behavior of these animals. Students then apply this information to learn more about microevolution when they compare DNA sequences. Finally, students learn about ELISA tests and consider the role of basic and applied science. This case study is appropriate for an introductory biology course for non-majors or majors.
In this problem-based learning/role playing case, students apply their knowledge of the biology of HIV/AIDS and antiretroviral therapy to developing foreign aid policy for the HIV/AIDS crisis in sub-Saharan Africa. The case was created for a non-majors course in human biology taken mostly by juniors or seniors. It has also been used in a microbiology course for pre-nursing students and in an upper-level microbiology course for biology majors.
This analysis case explores second-hand smoke and its impact on the decision to institute a smoking ban in the outdoor seating area of a popular coffee bar. In working through the case, students discuss the medical, ethical, legal, and societal issues of smoking in public areas. in addition, they devise experimental schemes for collecting data to determine how profitability is affected by a smoking ban. The case could be used in many science courses, including introductory biology and chemistry, in addition to liberal arts courses that deal with public policy, such as political science or civics. It could also be used in a course in public health or adapted to a business/management class.
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