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Anastasis: How cancer cells cheat death
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Apoptosis is a form of cell death that occurs as part of normal development. Once considered irreversible, apoptosis might not mark the end for all cells—including cancer cells. Growing evidence suggests that cancer cells can be rescued from the brink of death through a process called anastasis, which could explain how tumors resist anticancer therapies. From the Greek for “resurrection,” anastasis can occur through a variety of mechanisms, such as by arresting the activity of caspases, enzymes in charge of dismantling the cell during apoptosis by activating DNA repair mechanisms and by allowing cell fragments to fuse and continue living even after apoptosis has begun. Further studies are needed to explore how cancer cells cheat death through anastasis and how to adjust anticancer therapies accordingly..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
01/30/2023
Applying network science to better understand anesthetic drugs
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"For an anesthesiologist, medically induced transitions between conscious and unconscious brain states are just part of the daily routine. But precisely how general anesthetics produce a state of unconsciousness isn’t all that clear. That’s because researchers are missing a key piece to the puzzle: no one has been able to definitively pinpoint exactly where consciousness comes from. The prevailing idea is that there’s no single “seat” of consciousness – it’s more the product of multiple interactions occurring throughout the brain. A recent review article published in the journal Anesthesiology argues that, because of this global network property, the field of network science could provide the framework needed to more comprehensively understand the biological basis of consciousness…and by extension the principles underlying anesthetic-induced unconsciousness..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019