The physically demanding sport of competitive rowing is the backdrop for this case about homeostasis in which students follow the physiological changes that occur in an athlete competing in a 2000-meter race. The case was developed for use in a second-year anatomy and physiology course. It would also be appropriate in exercise and sports science classes.

Playfully alluding to Lewis Carroll's tale of Alice Through the Looking Glass, this case study considers the problems that would arise if a person were to cross over into a mirror-image environment. Students read about a drowsy undergraduate studying for a stereochemistry exam who finds herself in a place where spearmint gum tastes like caraway seed. The case emphasizes the lock-and-key theory of enzyme action and stresses the need for molecules to have the proper chirality if they are to be biologically useful. Designed for introductory organic chemistry and biochemistry courses, the case could also be used in biology courses.

In chronicling the life and death of a woman who developed diabetes as a teenager, this case study explores such basic science topics as metabolism, hormones, cell receptors, eye anatomy, and immunology as well as issues in nutrition, exercise, stem cell research, transplantation, drug delivery systems, genetic engineering, and health care. The case has been used in a physiology course as part of a unit on metabolism and hormonal control.

In this version, developed for classes in cell and molecular biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. This is the Cell & Molecular Biology Edition, which has a different set of questions than the General Biology Edition or the Human Anatomy& Physiology Edition, also in our collection.

In this version, developed for a course in general biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. The General Biology Edition is designed for an introductory biology course. Its basic storyline and core objectives are carried over into a Human Anatomy& Physiology Edition and a Cell& Molecular Biology Edition, also in our collection, each of which has its own set of questions.

In this version, developed for a course in human anatomy and physiology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. This is the Human Anatomy& Physiology Edition, which has a different set of questions than the General Biology Edition or the Cell& Molecular Biology Edition, also in our collection.

This case involves the transfer of a food allergy to a patient who received a combined kidney and liver transplant from a donor who died as the result of an allergic reaction. In addition to learning about the various roles of immune cells, the physiology of anaphylaxis, and the function of antibodies in immune physiology, students explore concepts related to histocompatibilities, organ donation, and organ rejection. The case is appropriate for use in a course in human physiology, a combined course in human anatomy and physiology, or an introductory course in immunology.

This case is based on an actual article entitled "Baby Alert" that appeared in Consumer Reports (May 1999). The article raises some concerns about the safety of polycarbonate baby bottles, and recommends that parents dispose of them as a precaution. However, the American Plastics Council and the Food and Drug Administration have raised concerns about the experimental methodology used as well as the recommendations made in this article. The case has been used to help develop students' critical thinking skills in an introductory chemistry course for non-majors. It may be used to illustrate applications in polymer chemistry, quantitative chemical analysis, toxicology, endocrine disruption, and risk-benefit analysis.

In this case study, two students meet a professor who surprises them by telling them that a biochemically important molecule's structure has been incorrectly represented in the published literature - in an article in the Proceedings of the National Academy of Sciences, a major biochemistry textbook, and even The Merck Index. The students are challenged to find the nature of the structural errors and correct them. In addition to demonstrating that the technical literature is not without its flaws, the case reviews important concepts related to geometric isomerism and tautomerism.

In this case study, students read about the injuries sustained by a young man hurt in a serious diving accident. To solve the case, they must determine the type of central nervous system injury described using their knowledge of the differences between symptoms and signs of brain and spinal cord injury. The case was developed for upper-level neuroscience courses and rehabilitation courses that cover the neuroanatomy of the central nervous system and the symptoms of different types of central nervous system injury.

This case study takes a combined directed and discussion approach to explore risk factors for breast cancer. After a preparatory reading assignment, students assess various medical histories derived from actual women with breast cancer and rank their overall risk for breast cancer and make recommendations for risk reduction. The task is complicated by the different and often combined sources of risk (e.g., reproductive history, hormone replacement therapy and family history). Originally written for an introductory biology course, the case study could easily be adapted for upper division curses in genetics, physiology, or biochemistry to explore the biological and biochemical basis underlying various risk factors.

"Samuel Dexter" is 52 years old, overweight, and a heavy smoker. He wakes one morning with weakness on his right side. When he attempts to walk to the bathroom, he stumbles and then falls. His wife, who suspects he has suffered a stroke, calls 911. Students read the short case scenario, including a brief clinical history of the patient and description of his injury, then answer a set of directed questions designed to probe the students' knowledge of the anatomy, physiology, and pathology underlying the patient's condition. The case has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.

"Amanda Richards," a 20-year-old junior in college, is majoring in biology and hopes to be a pediatrician one day. For about a month, she has been waking up frequently at night to go to the bathroom. Most recently, she has noticed that she needs to go to the bathroom during the day more often, almost houlyr. Students read about these symptoms and then answer a set of directed questions designed to teach facts and principles of physiology using reference books, textbooks, the Internet, and each other as sources of information. The case has been used in a sophomore-level course in human anatomy and physiology as well as in senior-level course in general physiology.

"Dolores Welborn," a 28-year-old attorney, is pregnant with her first child. Lately she has been tiring easily and is often short of breath. She has also had periods of light-headedness, cramping in her legs, and a sore tongue. Students read a brief clinical history and a description of signs and symptoms, then answer a set of directed questions designed to probe the underlying anatomy, physiology, and pathology of the Dolores's condition. In the process, they learn about the human hemolymphatic system. The case has been used in a sophomore-level course in human anatomy and physiology taught to pre-med and nursing students as well as in senior-level elective course in general physiology taken primarily by pre-med students.

"Allison Jacobson" is a 19-year-old sophomore majoring in pre-med. The past few weeks she has been studying for finals. She feels tired, even though she knows she has been getting enough sleep at night. She also has frequent headaches, and several times it has felt like her heart "missed a beat." Yesterday at lunch she fainted while waiting in line at the cafeteria. Students read a short description of the patient's history and symptoms, then answer a set of directed questions designed to probe their understanding of the anatomy, physiology, and pathology underlying the Allison's condition. The case has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.

Seven-year-old "Jason Hornbuckle" has been complaining for the past 12 hours of pain when he swallows. He also has a headache and has vomited twice. His mother decides to take him to the pediatrician. Students read a brief clinical history of the patient and a description of the relevant signs and symptoms, then answer a set of directed questions designed to probe the underlying anatomy, physiology, and pathology underlying Jason's condition. The case has been used in a sophomore-level course in human anatomy and physiology for pre-med and nursing students.

This clinical case study was developed to engage students by making connections between core concepts in chemistry and physiological processes in the body. The case pertains to medication-induced methemoglobinemia, its etiology, diagnosis, and treatments. Concepts taught by the case include the use of conversion factors, pH, buffering, Le Chatelier's principle, blood chemistry, and respiratory and metabolic acidosis and alkalosis. The case is suitable for use in a General, Organic, and Biological (GOB) Chemistry course or other introductory general chemistry course as well as undergraduate physiology courses. The case also could be adapted for use in undergraduate pharmacology and medicinal chemistry courses.

"Melanie Johnson" is a 32-year-old accountant who has moved to Green Bay, Wisconsin, from her hometown of Sarasota, Florida. For the first time in her life, she has been experiencing periods of depression, lethargy, and excessive sleeping. Students read about these symptoms then answer a set of directed questions designed to teach facts and principles of anatomy and physiology using reference books, textbooks, the Internet, and each other as sources of information. The case has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.

"Jason Hendrix," a 21-year-old student majoring in economics, is injured in a serious motorcycle accident while on spring break in Florida. Students read the short case scenario, which provides a brief clinical history of the patient and a description of his injury, then answer a set of directed questions designed to probe the students' knowledge of the anatomy, physiology, and pathology underlying the patient's condition. The case study has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.