OpenStax Biology 2e

Access, develop and share resources created by the OpenStax community that align with OpenStax Biology 2e. As of March 28, 2018, resources shared here pertain to OpenStax Biology 2e and not the original edition of OpenStax Biology.
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All resources in OpenStax Biology 2e

Biology, The Chemistry of Life, The Chemical Foundation of Life, Atoms, Isotopes, Ions, and Molecules: The Building Blocks

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By the end of this section, you will be able to:Define matter and elementsDescribe the interrelationship between protons, neutrons, and electronsCompare the ways in which electrons can be donated or shared between atomsExplain the ways in which naturally occurring elements combine to create molecules, cells, tissues, organ systems, and organisms

Material Type: Module

6.5 Nerves, Hormones & Homeostasis

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6.5 Nerves, Hormones & Homeostasis |‎Cached SimilarEssential Biology 6.5 Nerves, Hormones and Homeostasis .........o0O0o. ... Tutorial and game from think-bank ..... Online Learning ... Creative Commons License

Material Type: Diagram/Illustration, Interactive, Unit of Study

Author: Stephen Taylor

Introduction to Concepts in Statistics

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After the completion of this module, the student will be able to *read scatter plots and bar graphs *identify error bars on a graph *explain the role of a trend line *produce simple graphs in Excel The curricular materials contain a workbook (pdf and docx formats) and spreadsheets to work on the data and generate graphs.

Material Type: Activity/Lab, Homework/Assignment

Author: Claudia Neuhauser

Adolescent Health and Development

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The course consists of lectures, readings, discussions, panels of guest speakers, group and individual projects. The purpose of the lectures, readings, discussion and panels of guest speakers is to explore a variety of aspects of adolescence and adolescent health. The group and individual projects are meant to help students develop skills to work in multi-disciplinary teams and analyze adolescent health concerns through conceptual frameworks and recommend effective solutions through interventions.

Material Type: Full Course, Lecture Notes, Syllabus

Author: Blum, Robert

Case Studies in Primary Health Care

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This course introduces students to the origins, concepts, and development of community-based primary health care through case studies from both developing and developed countries. As in clinical bedside teaching, we use real cases to help students develop problem-solving skills in practical situations. We also discuss participatory approaches in the organization and management of health services and other factors such as equity, socio-cultural change, environmental protection, and the process of community empowerment.Included among this course's lecture materials are several recorded presentations by Carl Taylor, a giant in the field of international health. Dr. Taylor recorded the presentations for this course in January of 2008, just 2 years before he passed away in February of 2010.

Material Type: Full Course, Homework/Assignment, Lecture, Reading, Syllabus

Authors: Carl Taylor, Henry Perry, Henry Taylor

Child Health and Development

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This course focuses on the core processes of growth and development in early to middle childhood. Considers developmental theories, issues and research findings related to physical growth and cognitive, emotional, and social development. Considers appropriate instruments to assess growth and development. Evaluates efficacy of popular early intervention programs designed to enhance development in at-risk populations of children.

Material Type: Full Course, Homework/Assignment, Lecture, Lecture Notes, Reading, Syllabus

Authors: Lynne Michael Blum, Robert Blum

Epidemiology of Infectious Diseases

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Introduces the basic methods for infectious disease epidemiology and case studies of important disease syndromes and entities. Methods include definitions and nomenclature, outbreak investigations, disease surveillance, case-control studies, cohort studies, laboratory diagnosis, molecular epidemiology, dynamics of transmission, and assessment of vaccine field effectiveness. Case-studies focus on acute respiratory infections, diarrheal diseases, hepatitis, HIV, tuberculosis, sexually transmitted diseases, malaria, and other vector-borne diseases.

Material Type: Case Study, Full Course, Homework/Assignment, Lecture Notes, Syllabus

Author: Kenrad Nelson

Fundamentals of Epidemiology I

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Fundamentals of Epidemiology I is the first half of a course that introduces the basic concepts of epidemiology and biostatistics as applied to public health problems. Emphasis is placed on the principles and methods of epidemiologic investigation, appropriate summaries and displays of data, and the use of classical statistical approaches to describe the health of populations. Topics include the dynamic behavior of disease; usage of rates, ratios and proportions; methods of direct and indirect adjustment, and clinical life table which measures and describes the extent of disease problems.

Material Type: Full Course, Lecture Notes, Reading, Syllabus

Authors: Marie Diener-West, Sukon Kanchanaraksa

Human Growth and Development

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This course addresses essential learning outcomes in normal growth, development and nutrition across the lifespan, inclusive of aging. Its focus is on normal function rather than disease. Includes lectures, handouts, schedules, and student notes.

Material Type: Full Course, Lecture Notes, Lesson Plan, Student Guide

Antiobiotic Resistance

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In the explorable explanation players can learn how antibiotic resistance happens. They can interact with bacteria in this simulation to learn how when living things reproduce, there is a small amount of variance in their offspring. This allows organisms to respond to changes in their environment over several generations. Applied to bacteria, when they treated with antibiotics, only the strongest survive and multiply, creating an increasing resilient population.

Material Type: Activity/Lab, Game, Interactive, Simulation

Breathing Lessons

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Here learners investigate, diagnose, and assess the severity of emphysema in the lungs of three patients using transverse CT images of the upper and lower lungs. Students use the imaging software WebImage, a Web-based customized version of ImageJ, to determine the area of "dead air" in each section and hence the extent of emphysema.

Material Type: Activity/Lab, Diagram/Illustration, Interactive, Lesson Plan, Simulation, Unit of Study

Heart Attack and Blocked Arteries

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Dr. Rosenthal uses a model of a heart and an artery to describe how blockages lead to heart attack and tissue damage. This video presentation is also featured on the DVD Potent Biology: Stem Cells, Cloning, and Regeneration, available free from HHMI. This video is 51 seconds in length, and available in MOV (25 MB) and WMV (38 MB). All Stem Cells videos are located at:

Material Type: Lecture, Reading, Simulation

Author: Dr. Rosenthal

Medicines by Design

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Medicines By Design aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. Much of the most promising pharmacological research going on at universities across the country is sponsored by the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH), U.S. Department of Health and Human Services. Working at the crossroads of chemistry, genetics, cell biology, physiology, and engineering, pharmacologists are fighting disease in the laboratory and at the bedside.

Material Type: Textbook

Authors: National Institute of General Medical Sciences, National Institute of Health, US Department of Health and Human Services

Sometimes Less is Better: The Treatment of Thromboembolism

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"Ed Cramer" is a 47-year-old mechanical engineer who is being treated for venous thromboembolism. He was 45 when he first developed a blood clot in the lower part of his left leg and had to be hospitalized for five days. A year later, he developed a second blood clot, which almost killed him. This case study explores the physiology and treatment of venous thromboembolism, a condition which kills 60,000 people each year in the United States. The case was developed for use in graduate-level courses in medicine and pharmacy.

Material Type: Case Study

Authors: Angela Wisniewski, David Newberger, Thuy N. Nguyen

Virtual Cell Animation Collection

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The Virtual Cell Animation Collection currently contains 24 animations in 3D and with motion, which cover many molecular and cellular biology (MCB) topics. The Animation Collection is available on a website (, a YouTube channel (, and as an Apple iOS app. Biology education research indicates that 1) multiple viewing of animations increase learning gains beyond a single viewing either before a lecture, as in a “flipped” classroom, or during a lecture, 2) increased learning gains result from engagement with animations over engagement with static graphics, and 3) students perceive that engagement with animations greatly facilitates their understanding of MCB processes.

Material Type: Simulation

Authors: Alan White, Katie Reindl, Phillip McClean

Activities for engaging students in Biology using animations

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This resource includes three classroom-tested activities that were created using the ideas outlined in the article “Getting more out of animations” by Pruneski and Donovan (in press). The driving idea is that animations can be a powerful tool for learning complex biological processes, but when students are passive viewers, it limits their usefulness and may become simply another source of content to be memorized. Engaging students with animations can greatly increase the amount of information that can be extracted and can help students develop important learning skills that can be useful in the future. These sample assignments help make the use of animations more effective and active by structuring student viewing using guiding questions. These questions focus on particular objects, features, or steps of the process to help students accomplish specific learning objectives for that topic. The assignments also help students think about animations as media objects that are created by scientists and animators using specific tools and conventions that affect how the process is depicted and the ways in which it should be viewed. Lastly, by comparing and contrasting multiple animations of the same process, students can extract more information, overcome the limitations of each individual animations, and generate a more complete view of the process.

Material Type: Activity/Lab, Homework/Assignment

Authors: Stacey Kiser, Sam Donovan, Justin Pruneski