All resources in OpenStax Biology 2e

Pharmacogenetics: Using Genetics to Treat Disease

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This case study investigates the applications of genetics to medicine by exploring one of the first examples of a pharmacogenetic test to enter mainstream clinical practice. Pharmacogenetics examines how genetic variations in an individual correlate with responses to a specific medication in order to develop tailored medical treatments. Through a scenario based on clinical observations, students learn about acute lymphocytic leukemia as well as the wide range of individual responses to the drug used to treat it. Then, students interpret data similar to those initially published in scientific journals in order to construct an understanding of how genetic variation can be used to "tailor" medical care. Lastly, students are asked to apply their understanding of what they have learned in the case by making the appropriate medical recommendation based on a particular individual's genotype.

Material Type: Case Study

Author: Jeanne Ting Chowning

Biology, The Chemistry of Life, The Chemical Foundation of Life, Atoms, Isotopes, Ions, and Molecules: The Building Blocks

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By the end of this section, you will be able to:Define matter and elementsDescribe the interrelationship between protons, neutrons, and electronsCompare the ways in which electrons can be donated or shared between atomsExplain the ways in which naturally occurring elements combine to create molecules, cells, tissues, organ systems, and organisms

Material Type: Module

Biology

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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Material Type: Full Course

Diffusion, Osmosis and Active Transport

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Movement of ions in and out of cells is crucial to maintaining homeostasis within the body and ensuring that biological functions run properly. The natural movement of molecules due to collisions is called diffusion. Several factors affect diffusion rate: concentration, surface area, and molecular pumps. This activity demonstrates diffusion, osmosis, and active transport through 12 interactive models.

Material Type: Data Set, Lecture Notes, Simulation

Author: The Concord Consortium

Biology, Preface to Biology, Preface to Biology

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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Material Type: Module

6.5 Nerves, Hormones & Homeostasis

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6.5 Nerves, Hormones & Homeostasis | i-Biologyi-biology.net/ibdpbio/06-human-health.../nerves-hormones-homeostasis/‎Cached SimilarEssential Biology 6.5 Nerves, Hormones and Homeostasis .........o0O0o. ... Tutorial and game from think-bank ..... Online Learning ... Creative Commons License

Material Type: Diagram/Illustration, Interactive, Unit of Study

Author: Stephen Taylor

Introduction to Concepts in Statistics

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After the completion of this module, the student will be able to *read scatter plots and bar graphs *identify error bars on a graph *explain the role of a trend line *produce simple graphs in Excel The curricular materials contain a workbook (pdf and docx formats) and spreadsheets to work on the data and generate graphs.

Material Type: Activity/Lab, Homework/Assignment

Author: Claudia Neuhauser

Adolescent Health and Development

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The course consists of lectures, readings, discussions, panels of guest speakers, group and individual projects. The purpose of the lectures, readings, discussion and panels of guest speakers is to explore a variety of aspects of adolescence and adolescent health. The group and individual projects are meant to help students develop skills to work in multi-disciplinary teams and analyze adolescent health concerns through conceptual frameworks and recommend effective solutions through interventions.

Material Type: Full Course, Lecture Notes, Syllabus

Author: Blum, Robert

Case Studies in Primary Health Care

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This course introduces students to the origins, concepts, and development of community-based primary health care through case studies from both developing and developed countries. As in clinical bedside teaching, we use real cases to help students develop problem-solving skills in practical situations. We also discuss participatory approaches in the organization and management of health services and other factors such as equity, socio-cultural change, environmental protection, and the process of community empowerment.Included among this course's lecture materials are several recorded presentations by Carl Taylor, a giant in the field of international health. Dr. Taylor recorded the presentations for this course in January of 2008, just 2 years before he passed away in February of 2010.

Material Type: Full Course, Homework/Assignment, Lecture, Reading, Syllabus

Authors: Carl Taylor, Henry Perry, Henry Taylor

Child Health and Development

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This course focuses on the core processes of growth and development in early to middle childhood. Considers developmental theories, issues and research findings related to physical growth and cognitive, emotional, and social development. Considers appropriate instruments to assess growth and development. Evaluates efficacy of popular early intervention programs designed to enhance development in at-risk populations of children.

Material Type: Full Course, Homework/Assignment, Lecture, Lecture Notes, Reading, Syllabus

Authors: Lynne Michael Blum, Robert Blum

Epidemiology of Infectious Diseases

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Introduces the basic methods for infectious disease epidemiology and case studies of important disease syndromes and entities. Methods include definitions and nomenclature, outbreak investigations, disease surveillance, case-control studies, cohort studies, laboratory diagnosis, molecular epidemiology, dynamics of transmission, and assessment of vaccine field effectiveness. Case-studies focus on acute respiratory infections, diarrheal diseases, hepatitis, HIV, tuberculosis, sexually transmitted diseases, malaria, and other vector-borne diseases.

Material Type: Case Study, Full Course, Homework/Assignment, Lecture Notes, Syllabus

Author: Kenrad Nelson

Fundamentals of Epidemiology I

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Fundamentals of Epidemiology I is the first half of a course that introduces the basic concepts of epidemiology and biostatistics as applied to public health problems. Emphasis is placed on the principles and methods of epidemiologic investigation, appropriate summaries and displays of data, and the use of classical statistical approaches to describe the health of populations. Topics include the dynamic behavior of disease; usage of rates, ratios and proportions; methods of direct and indirect adjustment, and clinical life table which measures and describes the extent of disease problems.

Material Type: Full Course, Lecture Notes, Reading, Syllabus

Authors: Marie Diener-West, Sukon Kanchanaraksa

Human Growth and Development

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This course addresses essential learning outcomes in normal growth, development and nutrition across the lifespan, inclusive of aging. Its focus is on normal function rather than disease. Includes lectures, handouts, schedules, and student notes.

Material Type: Full Course, Lecture Notes, Lesson Plan, Student Guide

Antiobiotic Resistance

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In the explorable explanation players can learn how antibiotic resistance happens. They can interact with bacteria in this simulation to learn how when living things reproduce, there is a small amount of variance in their offspring. This allows organisms to respond to changes in their environment over several generations. Applied to bacteria, when they treated with antibiotics, only the strongest survive and multiply, creating an increasing resilient population.

Material Type: Activity/Lab, Game, Interactive, Simulation

Breathing Lessons

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Here learners investigate, diagnose, and assess the severity of emphysema in the lungs of three patients using transverse CT images of the upper and lower lungs. Students use the imaging software WebImage, a Web-based customized version of ImageJ, to determine the area of "dead air" in each section and hence the extent of emphysema.

Material Type: Activity/Lab, Diagram/Illustration, Interactive, Lesson Plan, Simulation, Unit of Study

Heart Attack and Blocked Arteries

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Dr. Rosenthal uses a model of a heart and an artery to describe how blockages lead to heart attack and tissue damage. This video presentation is also featured on the DVD Potent Biology: Stem Cells, Cloning, and Regeneration, available free from HHMI. This video is 51 seconds in length, and available in MOV (25 MB) and WMV (38 MB). All Stem Cells videos are located at: http://www.hhmi.org/biointeractive/stemcells/video.html.

Material Type: Lecture, Reading, Simulation

Author: Dr. Rosenthal

Medicines by Design

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Medicines By Design aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. Much of the most promising pharmacological research going on at universities across the country is sponsored by the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH), U.S. Department of Health and Human Services. Working at the crossroads of chemistry, genetics, cell biology, physiology, and engineering, pharmacologists are fighting disease in the laboratory and at the bedside.

Material Type: Textbook

Authors: National Institute of General Medical Sciences, National Institute of Health, US Department of Health and Human Services