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Human skin microbes change following chronic exposure to environmental pollutants
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Environmental pollution can have harsh effects on many systems in the body, but in addition to well-appreciated internal effects, pollutants can also harm our body’s outer barrier – our skin. Polyaromatic hydrocarbons (PAHs), organic molecules found in air pollution, can damage the skin. accelerating aging, altering skin pigmentation, and affecting pathways underlying acne and skin cancer. Unfortunately, exactly how PAH pollution harms the skin remains poorly understood. In a new study, researchers evaluated the cheek and scalp microbiota of over 200 individuals from two cities in China: one with high pollution levels and one with less PAH pollution. They found that individuals from the city with heavier pollution had higher PAH contamination of their skin, and certain bacteria were more prevalent in the high-PAH city, including some that contribute to skin conditions..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/03/2020
Introduction to Human Osteology
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CC BY-NC-ND
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This text was designed for use in the human osteology laboratory classroom. Bones are described to aid in identification of skeletonized remains in either an archaeological or forensic anthropology setting. Basic techniques for siding, aging, sexing, and stature estimation are described. Both images of bone and drawings are included which may be used for study purposes outside of the classroom. The text represents work that has been developed over more than 30 years by its various authors and is meant to present students with the basic analytical tools for the study of human osteology.

Subject:
Anatomy/Physiology
Life Science
Material Type:
Textbook
Provider:
Grand Valley State University
Provider Set:
ScholarWorks@GVSU
Author:
Georg Neumann
Gwyn Madden
Holm Neumann
Kenneth Beals
Roberta Hall
Date Added:
05/14/2012
Introduction to Psychology
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CC BY-NC-SA
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When you teach Introduction to Psychology, do you find it difficult — much harder than teaching classes in statistics or research methods? Do you easily give a lecture on the sympathetic nervous system, a lecture on Piaget, and a lecture on social cognition, but struggle with linking these topics together for the student? Do you feel like you are presenting a laundry list of research findings rather than an integrated set of principles and knowledge? Have you wondered how to ensure your course is relevant to your students? Introduction to Psychology utilizes the dual theme of behavior and empiricism to make psychology relevant to intro students. The author wrote this book to help students organize their thinking about psychology at a conceptual level. Five or ten years from now, he does not expect his students to remember the details of most of what he teaches them. However, he does hope that they will remember that psychology matters because it helps us understand behavior and that our knowledge of psychology is based on empirical study.

This is a derivative of INTRODUCTION TO PSYCHOLOGY by a publisher who has requested that they and the original author not receive attribution, which was originally released and is used under CC BY-NC-SA. This work, unless otherwise expressly stated, is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Subject:
Psychology
Social Science
Material Type:
Textbook
Provider:
University of Minnesota
Provider Set:
University of Minnesota Libraries Publishing
Date Added:
01/01/2017
Introduction to Sociology 2e
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CC BY
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Introduction to Sociology 2e adheres to the scope and sequence of a typical, one-semester introductory sociology course. It offers comprehensive coverage of core concepts, foundational scholars, and emerging theories, which are supported by a wealth of engaging learning materials. The textbook presents detailed section reviews with rich questions, discussions that help students apply their knowledge, and features that draw learners into the discipline in meaningful ways. The second edition retains the book’s conceptual organization, aligning to most courses, and has been significantly updated to reflect the latest research and provide examples most relevant to today’s students. In order to help instructors transition to the revised version, the 2e changes are described within the preface.

Subject:
Social Science
Sociology
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
02/01/2012
Introduction to Sociology 2e (superseded)
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CC BY
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Introduction to Sociology is intended for a one-semester introductory sociology course. Conceived of and developed by active sociology instructors, this up-to-date title and can be downloaded now by clicking on the "Get this book" button below. This online, fully editable and customizable title includes sociology theory and research; real-world applications; simplify and debate features; and learning objectives for each chapter

Note: this resource now links to the third edition, released in 2021. Its record is in OER Commons to allow users to see endorsements, reviews, etc...

Subject:
Social Science
Sociology
Material Type:
Textbook
Provider:
Rice University
Provider Set:
OpenStax College
Author:
Eric Strayer
Faye Jones
Gail Scaramuzzo
Jeff Bry
Nathan Keirns
Sally Vyain
Susan Cody-Rydezerski
Tommy Sadler
Date Added:
02/23/2015
Ion activity in mice offers insight into how to save stroke-stricken older brains
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A critical cellular process that occurs in the wake of a stroke in mice could hint at how to salvage otherwise compromised brain tissue. Strokes happen when the flow of blood to the brain is blocked, most often by a blood clot in a vessel. This creates two zones of injury: a central core and a radiating penumbra. Deprived of oxygen and glucose, brain cells in the core can die within minutes. Those in the penumbra are not as severely damaged. But if blood flow isn’t re-established within hours, those cells will succumb too. That’s why fast responses to strokes are so important—especially among the elderly, who are less resilient than younger sufferers of stroke. New research shows that that disparity between aged and young brains could be due to differences in calcium ion activity brought on by stroke. After inducing stroke in old and young mice, researchers found that spontaneous calcium activity was reduced in the brains of young mice, whereas it was increased in the brains of old mice..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Anatomy/Physiology
Applied Science
Health, Medicine and Nursing
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Isabel Allende: How to live passionately—no matter your age
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CC BY-NC-ND
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What do you plan on doing with your one wild and precious life?
Live it passionately.

When do we get old?
Society decides when we get old, usually around 65 they give us Medicare.
We start aging at birth, we are aging right now. We all experience it differently.

We all feel younger than our age cuz the spirit never dress.
Aging is attitude and health

Live passionately and presently in the moment.
How can i will myself to be passionate at an old age, with an open heart.
Say yes to life!!

Subject:
Arts and Humanities
Material Type:
Teaching/Learning Strategy
Date Added:
05/02/2017
It’s the fiber, not the fat: Significant effects of dietary challenge on the gut microbiome
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Today's obesity epidemic is driven by increased consumption of foods that are high in fat and low in soluble fiber, which alters the makeup of the gut microbiome. These changes also vary by age and sex, causing differences in susceptibility to obesity. Unfortunately, most animal studies compare diets that vary in both fat and fiber, making it difficult to determine which has an effect. Now, a new study suggests that fiber could play the more prominent role. The authors of the study profiled the microbial community in mice fed diets varying in either fiber or fat, but not both. 16S rRNA sequencing revealed that changes in fiber accounted for most of the variance in microbes. While these changes were age- and sex-specific, they were not dependent on dietary fat. Although further studies are needed to fully understand these effects, the results suggest that in animal obesity studies, the choice of control diet matters..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Nutrition
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/16/2020
MicroRNAs: Influencers and targets in hematopoietic stem cell aging
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Hematopoietic stem cells (HSCs) are immature cells that can develop into all types of blood cells, making them critical regulators of blood composition. However, during aging, HSCs undergo a process called senescence, in which their functionality starts to fade, leading to issues like reduced immune cell populations or leukemia. HSC senescence is influenced by various age-related factors, like accumulated DNA damage or epigenetic (non-DNA-altering) changes in gene expression, and it’s regulated by small RNA molecules known as microRNAs (miRNAs). For example, the miR-212/132 cluster binds to the FOXO3 gene to affect HSC life cycles, function, and survival and is upregulated with aging, while miR-125b, which can help HSCs resist stress and cell death, is downregulated in aging HSCs..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/01/2023
Neurology, Neuropsychology, and Neurobiology of Aging
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CC BY-NC-SA
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Lectures and discussions in this course cover the clinical, behavioral, and molecular aspects of the brain aging processes in humans. Topics include the loss of memory and other cognitive abilities in normal aging, as well as neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. Discussions based on readings taken from primary literature explore the current research in this field.

Subject:
Applied Science
Biology
Health, Medicine and Nursing
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Corkin, Suzanne
Ingram, Vernon
Date Added:
02/01/2005
New research brings causes of progeria into closer focus
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"St. Louis University researchers have discovered some of the molecular processes that lead to decline in patients with progeria. Their work also helps explain why certain drugs seemingly rejuvenate progeria cells, which could hint at more potent therapies against progeria. Hutchinson–Gilford progeria syndrome is a rare genetic disease that causes premature aging. Rapid aging of different tissues causes death by teenage years, normally due to cardiovascular complications. Currently, therapies for this devastating disease provide patients minimal benefit. The origin of progeria is a mutation in the lamin A gene—responsible for fabricating structural proteins that help keep the cell nucleus sturdy and the genome intact. The mutated lamin A protein “progerin” destabilizes the cell nucleus, causes DNA damage, and ultimately leads to the aging effects found in patients with progeria. Now, the researchers have delved deeper to understand how progerin wreaks damage at the molecular level..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Genetics
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Over the Hill - Aging on a Normal Curve
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Public Domain
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Students will use census data from a sample of 136 U.S. counties and other sample data to make estimates about the U.S. population that is 65 or older in all other counties and about other variables, using normal distribution models.

Subject:
Mathematics
Statistics and Probability
Material Type:
Activity/Lab
Provider:
U.S. Census Bureau
Provider Set:
Statistics in Schools
Date Added:
10/15/2019
Personal and Social Frameworks for Nutrition and Healthy Aging: Course website
Unrestricted Use
CC BY
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Provides an overview of the impact of nutrition on aging and the impact of aging on nutrient needs. Examines food access, procurement, preparation, and enjoyment using a socio-ecological framework of health and wellness. Evaluates age-associated psycho-social, economic, and environmental influences on individual food security and institutional program delivery. Emphasizes nutrition and food for healthy aging.

Learning Outcomes
Use an understanding of the relationship between nutrition and aging to identify challenges to healthy aging.
Create effective wellness promotion strategies that account for psycho-social, economic, and environmental influences on individuals and communities.
Apply knowledge of clinical, community, and commercial resources to promote the nutritional well-being of older adults.

Subject:
Life Science
Nutrition
Material Type:
Full Course
Author:
Debra Lippoldt
Jennifer Sasser
Kate Malone Kimmich
Radha Moghe
Rondi Schei
Sara Seely
Tanya Littrell
Date Added:
06/28/2019
Secondary Data Preregistration
Unrestricted Use
Public Domain
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Preregistration is the process of specifying project details, such as hypotheses, data collection procedures, and analytical decisions, prior to conducting a study. It is designed to make a clearer distinction between data-driven, exploratory work and a-priori, confirmatory work. Both modes of research are valuable, but are easy to unintentionally conflate. See the Preregistration Revolution for more background and recommendations.

For research that uses existing datasets, there is an increased risk of analysts being biased by preliminary trends in the dataset. However, that risk can be balanced by proper blinding to any summary statistics in the dataset and the use of hold out datasets (where the "training" and "validation" datasets are kept separate from each other). See this page for specific recommendations about "split samples" or "hold out" datasets. Finally, if those procedures are not followed, disclosure of possible biases can inform the researcher and her audience about the proper role any results should have (i.e. the results should be deemed mostly exploratory and ideal for additional confirmation).

This project contains a template for creating your preregistration, designed specifically for research using existing data. In the future, this template will be integrated into the OSF.

Subject:
Life Science
Social Science
Material Type:
Reading
Author:
Alexander C. DeHaven
Andrew Hall
Brian Brown
Charles R. Ebersole
Courtney K. Soderberg
David Thomas Mellor
Elliott Kruse
Jerome Olsen
Jessica Kosie
K.D. Valentine
Lorne Campbell
Marjan Bakker
Olmo van den Akker
Pamela Davis-Kean
Rodica I. Damian
Stuart J Ritchie
Thuy-vy Nguyen
William J. Chopik
Sara J. Weston
Date Added:
08/03/2021
Social Problems: Continuity and Change
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CC BY-NC-SA
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Social Problems: Continuity and Change is a textbook covering social problems, poverty, racial and ethnic inequality, gender and sexual diversity inequality, aging, substance abuse, crime, sexual behavior, family, schools and education, work and the economy, urban and rural problems, health and healthcare, population and the environment, war, and terrorism.

Subject:
Social Science
Sociology
Material Type:
Textbook
Provider:
The Saylor Foundation
Author:
Saylor Academy
Date Added:
02/15/2024
Transparency and Open Science Symposium GSA 2019
Unrestricted Use
Public Domain
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The past decade has seen rapid growth in conversations around and progress towards fostering a more transparent, open, and cumulative science. Best practices are being codified and established across fields relevant to gerontology from cancer science to psychological science. Many of the areas currently under development are of particular relevance to gerontologists such as best practices in balancing open science with participant confidentiality or best practices for preregistering archival, longitudinal data analysis. The present panel showcases one of the particular strengths of the open science movement - the contribution that early career researchers are making to these ongoing conversations on best practices. Early career researchers have the opportunity to blend their expertise with technology, their knowledge of their disciplines, and their vision for the future in shaping these conversations. In this panel, three early career researchers share their insights. Pfund presents an introduction to preregistration and the value of preregistration from the perspective of “growing up” within the open science movement. Seaman discusses efforts in and tools for transparency and reproducibility in neuroimaging of aging research. Ludwig introduces the idea of registered reports as a particularly useful form of publication for researchers who use longitudinal methods and/or those who work with hard-to-access samples. The symposium will include time for the audience to engage the panel in questions and discussion about current efforts in and future directions for transparent, open, and cumulative science efforts in gerontology.

Subject:
Life Science
Social Science
Material Type:
Reading
Author:
Eileen K Graham
Gabrielle N
Jennifer Lodi-smith
Kendra Leigh Seaman
Rita M
Date Added:
08/03/2021
Wild macaque gut microbiota lends insight into effects of age on the human gut microbiome
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Much recent research points toward a strong link between the microorganisms living in the gut and human health. Changes in this microbial community as a person grows older are thought to stem from changes in lifestyle and wellbeing associated with modern society, but evidence to support this claim is lacking. To gain a better understanding of how age affects the gut microbial community under natural conditions, researchers looked toward wild macaques. Using gene sequencing techniques, they found that the gut bacterial composition of individual macaques exhibited a unique personal signature and that this signature became increasingly unstable with age. This instability was linked to an increase in the relative abundance of rare bacterial groups. The uniqueness of an individual’s gut microbiota also increased with age, potentially due in part to a decrease in social interaction..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/14/2023