Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Explain the relationship between genotypes and phenotypes in dominant and recessive gene systemsDevelop a Punnett square to calculate the expected proportions of genotypes and phenotypes in a monohybrid crossExplain the purpose and methods of a test crossIdentify non-Mendelian inheritance patterns such as incomplete dominance, codominance, recessive lethals, multiple alleles, and sex linkage

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Most genetic studies of Alzheimer’s disease compare patient DNA to controls to identify mutations that increase disease risk. That approach has identified some risk variants, but none have led to effective treatments, and most of the genetic contributors are still unknown. Now, a team of researchers is tackling the problem from the opposite side, asking why some high-risk elderly people don’t have Alzheimer’s – a strategy that has discovered a protective mutation in a gene that may be a good drug target. To find protective mutations for Alzheimer’s, the scientists first searched the Utah Population Database for families with above-average rates of Alzheimer's that also had at least four people who were resilient to the disease -- that is, they were cognitively normal, despite being 75 years old or older, and having the APOE e4 allele, which increases risk more than 5-fold per copy..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

In this problem-based learning module, students will investigate the importance of genetic diversity will be explored by examining several case studies revealing consequences that can occur in individuals within a limited gene pool and how a variety of genes can lead to the survival of a species. Students will be able to create and interpret information from pedigree charts.

An introductory course in the molecular biology of the auditory system. First half focuses on human genetics and molecular biology, covering fundamentals of pedigree analysis, linkage analysis, molecular cloning, and gene analysis as well as ethical/legal issues, all in the context of an auditory disorder. Second half emphasizes molecular approaches to function and dysfunction of the cochlea, and is based on readings and discussion of research literature.

A video that makes the unspoken assumptions that we use in pedigree analysis explicit through a skit of two students solving a challenging pedigree question over videoconference. The students discuss certain pedigree assumptions which are often not mentioned in other pedigree teaching materials, even though they can be important to solving complex problems. The students recognize that not all assumptions are always applicable and sometimes we need to reconsider which assumptions to use.Includes two videos: a version without subtitles and a version with subtitles