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BIOL 3308-UNIT I-Control of the Cell Cycle
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:Understand how the cell cycle is controlled by mechanisms both internal and external to the cellExplain how the three internal control checkpoints occur at the end of G1, at the G2/M transition, and during metaphaseDescribe the molecules that control the cell cycle through positive and negative regulation

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
Adriana Visbal
Date Added:
08/21/2018
Biology
Unrestricted Use
CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
08/22/2012
Biology, The Cell, Cell Reproduction, Control of the Cell Cycle
Conditional Remix & Share Permitted
CC BY-NC
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0.0 stars

By the end of this section, you will be able to:Understand how the cell cycle is controlled by mechanisms both internal and external to the cellExplain how the three internal control checkpoints occur at the end of G1, at the G2/M transition, and during metaphaseDescribe the molecules that control the cell cycle through positive and negative regulation

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Date Added:
07/10/2017
Cancer-associated fibroblasts help tumors resist radiation therapy
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cancer-associated fibroblasts, or CAFs, make up 50 to 90% of a solid tumor’s volume. Embedded between a tumor’s core and healthy tissue, CAFs contribute to tumor initiation, progression, and invasion, and according to a new study, CAFs might also contribute to tumors’ ability to resist radiation therapy. Researchers coaxed CAFs to form by culturing normal fibroblasts with cancer cells from different tissues, including the breast, brain, lung, and prostate. Compared to normal fibroblasts, these CAFs showed less DNA damage from gamma ray radiation. This “radioresistance” was linked to DNA repair machinery deployed by CAFs. Treating CAFs with molecules inhibiting the repair of single- and double-stranded DNA reduced their defenses against radiation. Further insight into how CAFs communicate with surrounding cancer cells and healthy tissue could prove vital, as it could help researchers and clinicians find ways to topple tumors’ defenses against anticancer therapies..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/16/2021