Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Describe four types of signaling found in multicellular organismsCompare internal receptors with cell-surface receptorsRecognize the relationship between a ligand’s structure and its mechanism of action

This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular interactions, as well as the application of these quantitative analyses to biological problems across a wide range of levels of organization, from individual molecular interactions to populations of cells.

This article describes the following five basic terms that are essential to understand the coordination chemistry.1. Central ion/atom 2. Ligand3. Coordination Number 4. Coordination sphere and complex ion 5.Oxidation number of the central metal atom

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"(Pro)renin receptor, or (P)RR, is a cell receptor expressed throughout the body. Historically, knowledge about (P)RR has been limited to its functions in the heart and kidneys. But now, growing evidence suggests (P)RR plays a major role in various cancers. Over the last 5 years, researchers have discovered that certain cancers produce abnormally high amounts of (P)RR . which can trigger the formation of tumors in the pancreas, colon, and brain. A recently published review outlines the numerous newly recognized roles of (P)RR in cancer. as well as ways that (P)RR can be used against cancer. including as a target for monoclonal antibody therapy. To read the full review, visit biosignaling.biomedcentral..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"G protein-coupled receptors (GPCRs) are key proteins that help transmit extracellular signals into cells. Arrestin molecules help regulate GPCR signaling by recognizing and binding to GPCR residues that have been phosphorylated specifically by the kinase GRK. Two models, the barcode model and the flute model, have been proposed to explain this process. In the barcode model, different protein kinases produce different phosphorylation “barcodes” on GPCRs and arrestins “read” the barcodes produced by GRK to produce certain signaling outcomes. In the flute model, different phosphorylation patterns form different sequences of “notes”. These notes can then be “played” in various ways by the different structural features of arrestins, enabling multiple “songs” (outcomes) to be produced from one set of notes..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.