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Mobile Autonomous Systems Laboratory
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CC BY-NC-SA
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MASLab (Mobile Autonomous System Laboratory), also known as 6.186, is a robotics contest. The contest takes place during MIT's Independent Activities Period and participants earn 6 units of P/F credit and 6 Engineering Design Points. Teams of three to four students have less than a month to build and program sophisticated robots which must explore an unknown playing field and perform a series of tasks.
MASLab provides a significantly more difficult robotics problem than many other university-level robotics contests. Although students know the general size, shape, and color of the floors and walls, the students do not know the exact layout of the playing field. In addition, MASLab robots are completely autonomous, or in other words, the robots operate, calculate, and plan without human intervention. Finally, MASLab is one of the few robotics contests in the country to use a vision based robotics problem.

Subject:
Applied Science
Career and Technical Education
Computer Science
Electronic Technology
Engineering
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Kaelbling, Leslie
None, No Faculty
Date Added:
01/01/2005
Understanding molecular mechanisms of cholangiocarcinoma
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cholangiocarcinoma (CCA) is an aggressive form of cancer that forms in the biliary tract. CCA has high mortality and high rates of recurrence. While early diagnosis is critical, the molecular mechanisms by which CCA forms are poorly understood. A new study reports key interactions between three proteins during CCA development: TLR3, a mediator of both innate and adaptive immune responses and a promising target for anti-cancer therapy; IAP proteins that regulate apoptosis and orchestrate cancer cell death; and RIPK1, a multifunctional protein that regulates inflammation and cell death through apoptosis and necroptosis.TLR3 expression was found to be significantly higher in primary CCA tissue than in adjacent normal tissue. Meanwhile, Smac mimetic, an IAPs antagonist, sensitized CCA cell lines to TLR3 ligand, Poly(I:C)-induced apoptosis. This mode of cell death was switched to necroptosis in CCA cells expressing RIPK1, RIPK3, and MLKL..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2020