Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Define biodiversityDescribe biodiversity as the equilibrium of naturally fluctuating rates of extinction and speciationIdentify historical causes of high extinction rates in Earth’s history

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cancer-associated fibroblasts (CAFs) are part of the “soil” in which tumors grow. These cells have diverse origins and can interact with tumor cells in various ways, making it difficult to determine whether they’re friends or foes in cancer treatment. Detecting biomarkers can help address this challenge by allowing researchers to identify different CAF subsets. Several CAF biomarkers are associated with cancer promotion, such as FAP, vimentin, galectin 1, and osteopontin. For example, FAP increases cancer cell invasiveness and leads to immunotherapy resistance. Other CAF biomarkers are associated with cancer inhibition, like meflin, which is linked to a good prognosis in pancreatic and lung cancers. However, some biomarkers can either encourage or suppress cancer depending on the context..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Studying disease- and treatment-associated changes in bacterial abundance can clarify microbiome-related pathogenic and therapeutic mechanisms. However, the existing tests are not ideal for microbiome data, as they often have high positive rates or lack of power. Most of them also perform poorly when heterogeneous effects are present, and some are ill-suited for more than two groups or covariate adjustment. As an alternative, researchers recently developed a non-parametric zero-inflated quantile approach (ZINQ), which uses a two-part model. In part 1, logistic regression determines whether the variable of interest is associated with taxon presence/absence. In part 2, on selected quantile levels, quantile regression on the non-zero observations tests whether the variable is associated with altered taxon abundance. Finally, the marginal p-values are combined, with a significant aggregate p-value indicating differential abundance..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.