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The endometrial microbiota is associated with outcomes of assisted reproduction
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The composition of the vaginal microbiome is associated with pregnancy complications. However, it’s unclear whether the microbiome of the uterine lining (endometrium) is related to specific outcomes in patients undergoing assisted reproductive technology (ART). To find out, researchers recently analyzed the association of the endometrial microbiome with live birth, biochemical pregnancy, clinical miscarriage, and lack of pregnancy in 342 ethnically diverse infertile patients across 3 continents. 16S rRNA sequencing of endometrial fluid and biopsies before embryo transfer revealed that dysbiosis was related to poor reproductive outcomes. Specifically, increased proportions of pathogenic bacteria such as Gardnerella, Streptococcus, Atopobium, and Klebsiella were associated with a lack of live birth, while dominance of Lactobacillus bacteria was associated with live birth..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/16/2022