This page hosts training materials associated with the Northern Academy's Best Practices in …
This page hosts training materials associated with the Northern Academy's Best Practices in Emergency Response (ER) training. This hands-on, Safety Organized Practice (SOP)-based class offers participants advanced training in the use of best practices designed to enhance family engagement and balanced assessments during Child Welfare ER investigation, assessment and front end intervention services to improve outcomes and long-term safety for children.
Biology is designed for multi-semester biology courses for science majors. It is …
Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.
By the end of this section, you will be able to:List the …
By the end of this section, you will be able to:List the components of the endomembrane systemRecognize the relationship between the endomembrane system and its functions
This resource provides access to the Northern California Training Academy's extensive list …
This resource provides access to the Northern California Training Academy's extensive list of published guides, tips and tools for child welfare practice improvement.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Coronary heart disease is a serious condition, and its prognosis is largely determined by the degree of myocardial ischemia/reperfusion (MI/R) injury. MI/R injury occurs when blood returns to cardiac tissues and is partly a function of calcium overload and endoplasmic reticulum (ER) stress. There is growing evidence that estrogen is protective against MI/R injury and a recent study examined the potential mechanisms of this protective effect in rats and cultured cells. Reducing estrogen levels by removing both ovaries exacerbated MI/R injury and reduced levels of SERCA2a, a critical calcium ion pump, but SERCA2a could be increased to nearly normal levels by estrogen supplementation (17β-estradiol). Both supplemental estrogen and exogenous SERCA2a overexpression decreased signs of ER stress and alleviated myocardial damage. Conversely, reducing SERCA2a expression exacerbated ER stress and myocardial damage, and adding estrogen after that reduction could not protect against the damage or ER stress..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
Keynote presentations, workshop materials, and other helpful resources from the 2020 Partnerships …
Keynote presentations, workshop materials, and other helpful resources from the 2020 Partnerships for Well-Being Institute hosted by Human Services at UC Davis Continuing and Professional Education. This includes content from both the June 3 Virtual Mini-Institute and the in-person institute currently scheduled for Dec. 8-10 in Garden Grove, CA.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Multiple myeloma (MM) is a common type of plasma cell cancer that remains aggressive and incurable despite the development of several treatments. Approximately 70–80% of patients with MM have myeloma bone disease, which involves bone fractures and high blood calcium (Ca2+) and affects MM prognosis. Various calcium channels and transporters help balance calcium levels, so they may be closely related to MM prognosis. For example, plasma membrane calcium channels allow calcium ions to enter cells, while proteins involved in store-operated calcium entry (SOCE) mediate calcium release from sites in the endoplasmic reticulum (ER)/sarcoplasmic reticulum (SR). Mitochondrial calcium channels regulate calcium uptake into mitochondria, which contributes to SOCE, and calcium-ATPases pump calcium ions from the cytoplasm back into the ER/SR or extracellular space. These molecules have been reported to be altered in the context of MM, but the specific mechanism by which their dysfunction leads to MM remains unclear..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Chronic infection with the hepatitis C virus is a major cause of chronic liver disease, even after the virus has been eradicated by antiviral treatment. The problem appears to lie in the lingering activation of harmful Wnt/β-catenin signaling, which active viruses exploit for replication. A new study suggests the enzyme PKA could play a role. PKA is part of a signaling cascade that is activated during hepatitis C infection. To determine its role, researchers prevented PKA activation by treating cells with a PKA inhibitor. Inhibition was found to be beneficial. Inhibiting PKA reduced cells’ capacity to support both the hepatitis C virus and Wnt/β-catenin signaling, as mediated by another enzyme, GSK-3β. Interestingly, similar benefits were observed when another harmful effect of viral infection was repressed, namely, endoplasmic reticulum stress..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
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