The Maryland State Department of Education is working to prevent the misuse and abuse of opioids. This is a student-centered lesson for the 9-12 grade band. This lesson can be modified or remixed to meet the needs of the students you teach.  The content of this lesson includes students identifying and analyzing influences that could lead to drug use. Students are then tasked with forming strategies to overcome factors and influences that could lead to drug use.

Anatomy and Physiology is a dynamic textbook for the two-semester human anatomy and physiology course for life science and allied health majors. The book is organized by body system and covers standard scope and sequence requirements. Its lucid text, strategically constructed art, career features, and links to external learning tools address the critical teaching and learning challenges in the course. The web-based version of Anatomy and Physiology also features links to surgical videos, histology, and interactive diagrams.

In the present moment, the centrality of the criminal justice in how our society approaches substance use and abuse is under renewed scrutiny.  Students will independently read and watch videos assigned by the instructor and address in a critical and reflective manner on how social work practice with people who use drugs would be different in a world where drug use was not criminalized. 

Drug research has contributed more to the progress of medicine during the past century than any other scientific factor. With lecture snippets of Gerhard Domagk, Gertrude Elion and Brian Kobilka this Mini Lectures introduces to the fundamental research methods of drug targeting.

Welcome to Chemistry Applications: Pharmacology, Biotechnology and Forensics, a high school curriculum. Included in this curriculum are many lesson plans that are aligned with the North Carolina Chemistry and Biology Standards, in addition to the National Science Standard. Students will learn to be critically thinking, problem solving individuals who will relate science to the real world.

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This class examines the relationship between a number of mind-altering substances and cultural processes. We look at the relationship between drugs and such phenomena as poverty, religion, technology, inter-generational conflict, colonialism, and global capitalism. We read about the physiological and psychological effects of these substances -- ranging from alcohol to LSD, cocaine and ecstasy -- and ask why different societies prohibit and sanction different drugs. We examine the use of mind-altering substances in a number of "traditional" societies, and follow the development of a global trade in such substances as sugar, coffee, tea, nicotine, cocaine, and marijuana concurrent with the evolution of global capitalism. We look at the use of LSD as a mind-control substance by the CIA and as a mind-altering substance in the 1960's counter-culture, and we look at the rise of Prozac® and Viagra® as popular, if controversial, pharmaceutical products in recent years. Finally, we evaluate America's current drug laws.

This class is a multidisciplinary introduction to pharmacology, neurotransmitters, drug mechanisms, and brain diseases from addiction to schizophrenia.
From Abilify® to Zyrtec®, the world is full of fascinating drugs. If you are poisoned by sarin nerve gas, you may be able to save your life by huffing some BZ nerve gas. This class will explain that chemical curiosity, along with a host of other interesting tidbits of pharmacology. The structure of the class interleaves basic concepts with specific examples and entertaining tangents, so it is not loaded with boring abstract theory. In the first class you will learn what a neurotransmitter is, and you will immediately apply that knowledge when we discuss the mechanism of caffeine. The class is highly multidisciplinary, including topics such as patent law, medical ethics, history, and the physics of crack pipes.

The Course book presents the basics of drugs quality control in accordance with regulatory documents (pharmacopoeia of Europe, USA, Japan, Russia) and new data from current scientific periodicals, monographs The features of the physical, spectral and chemical quality control of medicines according to the indicators «identification», «tests» and «assay» are described in detail. Part II presents a workbook, which includes questions for the self-control of the material studied and tasks for a laboratory workshop. The Course book contains reference material and samples of pharmacopoeial articles. The Course book is designed for students of the specialty «Pharmacy».

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Neuromyelitis optica spectrum disorder, or NMOSD, is a rare auto-immune demyelinating disease of the central nervous system. Now considered a separate disorder from multiple sclerosis, NMOSD can be severely disabling and life-threatening, with a reported mortality of between 7 and 32%. The hallmark of the disease is recurrent attacks of optic neuritis and/or transverse myelitis that result in accumulating, irreversible disability, including blindness and paraplegia. Approximately 75 to 90% of patients with NMOSD have a disease-specific, pathogenic IgG autoantibody against the aquaporin-4 water channel, or AQP4. This antibody is thought to bind to AQP4 on astrocyte foot processes at the blood-brain barrier. This causes damage to astrocytes and the blood-brain barrier itself through several mechanisms, including the formation of the membrane attack complex through activation of the complement component C5b9..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"NTRK, ROS1, and ALK gene fusions are recognised oncodrivers in many cancers. Oncogenic fusions result in constitutively active tyrosine kinases and downstream activation of pathways associated with tumour growth, survival, and proliferation. NTRK fusions, for example, are found in both adult and paediatric cancers and are extremely common in some rare cancers. All three fusion types are found in non–small cell lung cancer. At diagnosis, many patients with NTRK-fusion-positive solid tumours, including NTRK-positive non–small cell lung cancer, or with ROS1-positive non–small cell lung cancer also have brain metastases. These metastases are linked to a worse prognosis. Although effective drugs exist for both NTRK-positive solid tumours and ROS1-positive non–small cell lung cancer, most don’t penetrate the CNS well enough to treat brain metastases. Entrectinib, an orally active small-molecule tyrosine kinase inhibitor that selectively inhibits TRK, ROS1 and ALK, acts in both the periphery and the CNS..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets.

Small molecules are chemicals that can interact with proteins to affect their functions. Learn about the structure and biological functions of various small molecules like sugar and caffeine. Also featured on the HHMI DVD, Scanning Life's Matrix: Genes, Proteins, and Small Molecules. Available free from HHMI.

Links for Parents to use at home and then links for Teachers to use at different grade levels (National Institute on Drug Abuse)

A charts that list commonly abused drugs, their street names, DEA schedule, how they are administered, intoxication effects, and potential health consequences. (National Institute on Drug Abuse)

Natural High Presentations give students the opportunity to explore activities that give them a natural high and share it with others by answering the required questions and demonstrating or giving a visual example of their natural high.This assignment can be done in a brick and mortar classroom in person as well as in an online classroom using a program such as Flipgrid.

Explore the discovery and understanding of marine symbionts that may provide novel sources of new drugs with Scripps Institutions' Margo Haygood. (27 minutes)

Join Scripps Institution's Bill Fenical and learn how recent discoveries of antibiotic-producing Bacteria in the deep oceans suggest that the last remaining resource for new Antimicrobial drugs may well be the microorganisms that inhabit the oceans. (56 minutes)