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2017 Updates to the Banff Classification of Allograft Pathology
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Since 1991, the international Banff Classification has been revisited every 2 years to integrate advances in clinical research into best-treatment practices for organ transplantation. At the 2017 Banff conference, 479 delegates from 23 countries reviewed two seminal concerns in the kidney-transplant field: how T cell-mediated rejection is related to inflammation in areas of interstitial fibrosis and tubular atrophy, and the evolution of molecular diagnostics, particularly for identifying antibody-mediated rejection. These discussions prompted significant updates to the Banff scheme. The relationship between i-IFTA severity and graft survival has been well established. Despite this, i-IFTA has previously been excluded as a diagnostic criterion of TCMR. Recent findings, however, suggest that inflammation in IFTA can be a manifestation of chronic active TCMR, particularly when other features of T cell-mediated alloimmunity, such as tubulitis, are present..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Biology
Unrestricted Use
CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
08/22/2012
Biology, Biological Diversity, Viruses, Virus Infections and Hosts
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:List the steps of replication and explain what occurs at each stepDescribe the lytic and lysogenic cycles of virus replicationExplain the transmission and diseases of animal and plant virusesDiscuss the economic impact of animal and plant viruses

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Date Added:
07/10/2017
Hope for a cure: Attacking the inflammatory origins of cholesteatoma
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cholesteatoma is abnormal skin growth in the middle section of the ear. The resulting damage can lead to hearing loss and even facial paralysis. Unfortunately, no medical cure for cholesteatoma currently exists, and while surgical removal of excess tissue can be effective, 12 to 30% of patients show a recurrence of cholesteatoma. To understand how this abnormality forms and returns in some cases, researchers examined cholesteatoma tissue in the lab. Experiments showed that inflammatory signaling caused overactive skin cell growth. That signaling was largely mediated by the transmembrane protein TLR4, a molecule that helps orchestrate the innate immune response during infection and injury. Signs of cholesteatoma were effectively reduced by suppressing TLR4 activity with LPS-RS, a TLR4 antagonist and toxin derived from photosynthetic bacteria..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/16/2021
Stress, Inc.
Read the Fine Print
Educational Use
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Students explore the physical and psychological effect of stress and tension on human beings. Concepts of stress and stress management are introduced. Students discover how perception serves to fuel a huge industry dedicated to minimizing risk and relieving stress. Students complete a writing activity focused on developing critical thinking skills. Note: The literacy activities for the Mechanics unit are based on physical themes that have broad application to our experience in the world concepts of rhythm, balance, spin, gravity, levity, inertia, momentum, friction, stress and tension.

Subject:
Applied Science
Engineering
Psychology
Social Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise Carlson
Jane Evenson
Malinda Schaefer Zarske
Date Added:
09/26/2008
Who's Down the Well?
Read the Fine Print
Educational Use
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Drinking water comes from many different sources, including surface water and groundwater. Environmental engineers analyze the physical properties of groundwater to predict how and where surface contaminants will travel. In this lesson, students will learn about several possible scenarios of contamination to drinking water. They will analyze the movement of example contaminants through groundwater such as environmental engineers must do (i.e., engineers identify and analyze existing contamination of water sources in order to produce high quality drinking water for consumers).

Subject:
Applied Science
Engineering
Hydrology
Physical Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Janet Yowell
Malinda Schaefer Zarske
Melissa Straten
Date Added:
09/18/2014