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Bacterial Gene Transfer Chapter 3
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This laboratory investigates one form of genetic recombination in bacteria. This process, ...

This laboratory investigates one form of genetic recombination in bacteria. This process, called conjugation, occurs when one bacteria transfers DNA to another bacteria. Two different strains of Escherichia coli are used: an Hfr strain with the F factor integrated into the bacterial chromosome acting as the donor, and an F-strain lacking the fertility factor acting as a recipient. The F-strain is auxotrophic for certain genetic markers and the ordered transfer of markers from the Hfr strain to the F-strain is used to map gene locations on the bacterial chromosome.

Subject:
Biology
Material Type:
Activities and Labs
Lesson Plans
Provider:
Association for Biology Laboratory Education (ABLE)
Author:
John Mordacq
Roberta Ellington
DNA Build
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Students reinforce their knowledge that DNA is the genetic material for all ...

Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Engineering
Genetics
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Denise W. Carlson
Integrated Teaching and Learning Program,
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Finding a Gene on the Chromosome Map
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In this activity, learners use pedigree and jigsaw puzzles to explore how ...

In this activity, learners use pedigree and jigsaw puzzles to explore how scientists use genetic information from a family to identify a gene associated with a genetic disorder. This activity will help learners explore the basics of human genetics including chromosomes, alleles, inheritance, mutations, and genetic pedigrees.

Subject:
Genetics
Material Type:
Activities and Labs
Games
Images and Illustrations
Instructional Material
Lesson Plans
Simulations
Provider:
Genetic Science Learning Center
NSDL Staff
Science and Math Informal Learning Educators (SMILE)
Provider Set:
Teach.Genetics
Key Concepts in Biology
SMILE Pathway: Science and Math Activities in One Search
Author:
April Mitchell
Ellen T. Wilson
Howard Hughes Medical Institute Precollege Science Education Initiative for Biomedical Research Institutions Award
Jennifer Logan
Louisa Stark
The University of Utah
University of Utah
Genetics
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Genetics is the branch of biology that studies the means by which ...

Genetics is the branch of biology that studies the means by which traits are passed on from one generation to the next and the causes of similarities and differences between related individuals. In this course, the student will take a close look at chromosomes, DNA, and genes. The student will learn how hereditary information is transferred, how it can change, how it can lead to human disease and be tested to indicate disease, and much more. Upon successful completion of this course, students will be able to: give a brief synopsis of the history of genetics by explaining the fundamental genetic concepts covered in this course as they were discovered through time; identify the links between Mendel's discoveries (often represented by Punnett squares) with mitosis and meiosis, dominance, penetrance, and linkage; recognize the role of simple probability in genetic inheritance; apply advanced genetic concepts, including genetic mapping and transposons, to practical applications, including pedigree analysis and corn kernel color; identify the cause behind several genetic diseases currently prevalent in society (such as color blindness and hemophilia) and recognize the importance of genetic illness throughout history; compare and contrast advanced concepts of chromosomal, bacterial, human, and population genetics; recognize the similarities and differences between nuclear, chloroplast, and mitochondrial DNA; describe the fundamentals of population genetics, calculate gene frequencies in a give scenario, predict future gene frequencies over future generations, and define the role of evolution in gene frequency shift over time; recall, analyze, synthesize, and build on the foundational material to then learn the cutting-edge technological advances in genetics, including genomics, population and evolutionary genetics, and QTL mapping. (Biology 305)

Subject:
Biology
Genetics
Material Type:
Activities and Labs
Assessments
Audio Lectures
Full Course
Homework and Assignments
Lecture Notes
Readings
Simulations
Syllabi
Video Lectures
Provider:
The Saylor Foundation
Inside DNA
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In this activity (on pages 34-39), learners make a fairly detailed model ...

In this activity (on pages 34-39), learners make a fairly detailed model of DNA using licorice and gumdrops. The sugar and phosphate backbone of DNA is represented by alternating red and black licorice, and the base pairs are represented by gumdrops arranged so that gumdrop colors are paired. After a pair of learners have made a DNA section, they find another team and link them up to make a model of a gene. They then split the model and "copy" it using the base pair rules from earlier, comparing their copy to the original to see if there are any differences (mutations).

Subject:
Life Science
Genetics
Chemistry
Anthropology
Material Type:
Activities and Labs
Data
Instructional Material
Provider:
Science and Math Informal Learning Educators (SMILE)
University of Nebraska State Museum, Nebraska 4-H Youth Development
Provider Set:
SMILE Pathway: Science and Math Activities in One Search
Author:
Howard Hughes Medical Institute
Nebraska Cooperative Extension 4-H Youth Development
NSF Informal Science Education Program
University of Nebraska State Museum
Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made ...

Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell. For comparison, multiple eggs can be prepared representing different species and their DNA. Introduce the demonstration by talking about the actual size of cells and DNA. Activity contains extension questions to assess learners' understanding.

Subject:
Engineering
Life Science
Mathematics
Chemistry
Material Type:
Activities and Labs
Data
Instructional Material
Lesson Plans
Simulations
Provider:
Science and Math Informal Learning Educators (SMILE)
Provider Set:
SMILE Pathway: Science and Math Activities in One Search
Author:
American Society for Microbiology
David R. Wessner, Ph.D.
Mark Gallo, Ph.D.
Meiosis
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Meiosis is the process by which gametes (eggs and sperm) are made. ...

Meiosis is the process by which gametes (eggs and sperm) are made. Gametes have only one set of chromosomes. Therefore, meiosis involves a reduction in the amount of genetic material. Each gamete has only half the chromosomes of the original germ cell. Explore meiosis with a computer model of dragons. Run meiosis, inspect the chromosomes, then choose gametes to fertilize. Predict the results of the dragon offspring and try to make a dragon without legs. Learn why all siblings do not look alike.

Subject:
Life Science
Genetics
Mathematics
Material Type:
Activities and Labs
Data
Instructional Material
Lecture Notes
Provider:
Concord Consortium
Provider Set:
Concord Consortium Collection NGSS Aligned Records
Author:
The Concord Consortium
Sex Determination: More Complicated Than You Thought
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From something as small and complex as a chromosome to something as ...

From something as small and complex as a chromosome to something as seemingly simple as the weather, sex determination systems vary significantly across the animal kingdom. Biologist and teacher Aaron Reedy shows us the amazing differences between species when it comes to determination of gender. A quiz, thought provoking question, and links for further study are provided to create a lesson around the 6-minute video. Educators may use the platform to easily "Flip" or create their own lesson for use with their students of any age or level.

Subject:
Women's Studies
Material Type:
Video Lectures
Provider:
TED
Provider Set:
TED-Ed
Author:
Reedy, Aaron
Techniques in Karyology: The Bone Marrow Extraction Method
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This 2-hour laboratory exercise isolates chromosomes from bone marrow. After the chromosomes ...

This 2-hour laboratory exercise isolates chromosomes from bone marrow. After the chromosomes are isolated, they are stained and chromosomal spreads are examined microscopically to establish diploid number and chromosome morphology. This technique is applicable to all small mammals.

Subject:
Biology
Material Type:
Activities and Labs
Lesson Plans
Provider:
Association for Biology Laboratory Education (ABLE)
Author:
Deanna Tolliver
Lynn Robbins
What Sort?
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In this activity (on pages 22-33), learners do the kind of work ...

In this activity (on pages 22-33), learners do the kind of work genetic scientists do, sorting and comparing (images of) genetic material strands called chromosomes. First, learners use two meters of thread to represent the length of DNA in a cell. Then, using a special chart called a karyotype, learners sort the genetic material of three babies based on the size and pattern of each chromosome. The introductory "What We Know" section introduces the concepts of genes, chromosomes, and genetic science.

Subject:
Life Science
Genetics
Chemistry
Anthropology
Material Type:
Activities and Labs
Instructional Material
Provider:
Science and Math Informal Learning Educators (SMILE)
University of Nebraska State Museum, Nebraska 4-H Youth Development
Provider Set:
SMILE Pathway: Science and Math Activities in One Search
Author:
Howard Hughes Medical Institute
National Science Foundation Informal Science Education Program
Nebraska Cooperative Extension 4-H Youth Development
University of Nebraska State Museum
Who Robbed the Bank?
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Students use DNA profiling to determine who robbed a bank. After they ...

Students use DNA profiling to determine who robbed a bank. After they learn how the FBI's Combined DNA Index System (CODIS) is used to match crime scene DNA with tissue sample DNA, students use CODIS principles and sample DNA fragments to determine which of three suspects matches evidence obtain at a crime location. They communicate their results as if they were biomedical engineers reporting to a police crime scene investigation.

Subject:
Engineering
Genetics
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Denise W. Carlson
Frank Burkholder
Integrated Teaching and Learning Program,
Malinda Schaefer Zarske