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Alirocumab lowers atherogenic lipids in patients with metabolic syndrome to potentially lower cardiovascular risk
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Individuals with metabolic syndrome have a 2-fold increased risk of cardiovascular disease, but few strategies provide adequate cardiovascular risk reduction for this group. One option to lower this risk is to reduce atherogenic lipids, particularly low-density lipoprotein cholesterol. Statins are a recommended first-line therapy for this purpose, but this approach doesn’t always provide sufficient LDL-C lowering to optimally reduce cardiovascular risk. Now, researchers have shown that alirocumab, a proprotein converstase subtilisin/kexin type 9 inhibitor, or PCSK9 inhibitor, approved for LDL-C reduction, may address this need. Pooled clinical trial data from ten phase 3 clinical trials from the ODYSSEY clinical development program showed alirocumab significantly lowered LDL-C in individuals both with and without metabolic syndrome..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Biology
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CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
08/22/2012
Biology, The Cell, Cell Communication, Response to the Signal
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:Describe how signaling pathways direct protein expression, cellular metabolism, and cell growthIdentify the function of PKC in signal transduction pathwaysRecognize the role of apoptosis in the development and maintenance of a healthy organism

Subject:
Applied Science
Biology
Material Type:
Module
Date Added:
07/10/2017
Biology, The Cell, Cellular Respiration, Connections of Carbohydrate, Protein, and Lipid Metabolic Pathways
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CC BY-NC
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By the end of this section, you will be able to:Discuss the ways in which carbohydrate metabolic pathways, glycolysis, and the citric acid cycle interrelate with protein and lipid metabolic pathwaysExplain why metabolic pathways are not considered closed systems

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Date Added:
07/10/2017
Cellular Metabolism For Anatomy and Physiology : Introduction (04:01)
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CC BY-ND
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Anatomy and Physiology students must know the basics of cellular metabolism. This is an introduction to cellular metabolism.

Lesson 1 in our Cellular Metabolism For Anatomy and Physiology series. This is part of our Anatomy and Physiology lecture series.

If this video helps you please be sure to LST -like subscribe and tell your friends. Your support help us make more videos. For the complete series please visit http://mrfordsclass.net/

Videos in cell biology series:
- Introduction (04:01): http://youtu.be/efzWdP-i3Jo
- Respiration Fundamentals (04:02): http://youtu.be/5BIVqFptifc

Subject:
Anatomy/Physiology
Life Science
Material Type:
Lecture
Provider:
Mr. Ford's Class
Author:
Scott Ford
Date Added:
10/02/2014
Cellular Metabolism For Anatomy and Physiology : Respiration Fundamentals (04:02)
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CC BY-ND
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We introduce the general formula for cellular respiration as well as cover the difference between aerobic and anaerobic respiration.

Lesson 2 in our Cellular Metabolism For Anatomy and Physiology series. This is part of our Anatomy and Physiology lecture series.

If this video helps you please be sure to LST -like subscribe and tell your friends. Your support help us make more videos. For the complete series please visit http://mrfordsclass.net/

Videos in cell biology series:
- Introduction (04:01): http://youtu.be/efzWdP-i3Jo
- Respiration Fundamentals (04:02): http://youtu.be/5BIVqFptifc

Subject:
Anatomy/Physiology
Life Science
Material Type:
Lecture
Provider:
Mr. Ford's Class
Author:
Scott Ford
Date Added:
10/02/2014
Gene Machine: The Lac Operon
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CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Life Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Spiegelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
Gene Machine: The Lac Operon (AR)
Unrestricted Use
CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Life Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Speigelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
Optotracing: Getting the most out of plant biomass
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Take. Make. Dispose. Long the mantra of modern industry, this linear model of economic growth is unsustainable. It has drained the planet of natural resources and amplified the climate-altering effects of human activity. Fortunately, it’s not too late to turn it around. The United Nations’ 2030 Agenda for Sustainable Development outlines a plan of action for preserving peace, people, prosperity, and our planet. Central to that plan is the promotion of a new industrial model of reduction, reuse, and recycling. Scientists from Sweden are taking up that cause in an unlikely but impactful place: inside plants. Biomass is a highly underutilized natural resource. Currently, humans use only about 3.5% of net growth of global biomass. It’s not hard to envision how adding more biomass to the world’s current energy mix could substantially offset harmful fossil fuels..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/27/2019
A new herbal formulation shows demonstrated clinical efficacy and safety in promoting weight loss
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A new clinical trial has shown promising results for those trying to shed excess pounds: researchers have zeroed in on a combination of herbal extracts that can significantly increase weight loss under the right circumstances. The news could mean better health for the more than 1 billion people who are overweight or obese worldwide. Traditional pharmaceutical and surgical options for weight management are expensive and often associated with adverse effects. The herbal formulation – composed of extracts from three common culinary spices used in Indian cooking – was developed as a high-quality natural alternative. The combination tackles excess body weight through a multi-layered approach, by both preventing fat cells from maturing and boosting existing fat break down. To determine the safety and efficacy of the extracts, researchers performed a randomized, double-blind, placebo-controlled clinical trial with healthy overweight adults..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019