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Biology
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
08/22/2012
Biology, Animal Structure and Function, The Circulatory System, Mammalian Heart and Blood Vessels
Conditional Remix & Share Permitted
CC BY-NC-SA
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By the end of this section, you will be able to:Describe the structure of the heart and explain how cardiac muscle is different from other musclesDescribe the cardiac cycleExplain the structure of arteries, veins, and capillaries, and how blood flows through the body

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
Tina B. Jones
Date Added:
07/24/2019
Biology, Animal Structure and Function, The Circulatory System, Mammalian Heart and Blood Vessels
Conditional Remix & Share Permitted
CC BY-NC
Rating
0.0 stars

By the end of this section, you will be able to:Describe the structure of the heart and explain how cardiac muscle is different from other musclesDescribe the cardiac cycleExplain the structure of arteries, veins, and capillaries, and how blood flows through the body

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Date Added:
07/10/2017
Blood Clots, Polymers and Strokes
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Educational Use
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Students are introduced to the circulatory system with an emphasis on the blood clotting process, including coagulation and the formation and degradation of polymers through their underlying atomic properties. They learn about the medical emergency of strokes the loss of brain function commonly due to blood clots including various causes and the different effects depending on the brain location, as well as blood clot removal devices designed by biomedical engineers.

Subject:
Applied Science
Education
Engineering
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Ann McCabe
Azim Laiwalla
Carleigh Samson
Victoria Lanaghan
Date Added:
09/18/2014
Body Circulation
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Educational Use
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Students are introduced to the circulatory system, the heart, and blood flow in the human body. Through guided pre-reading, during-reading and post-reading activities, students learn about the circulatory system's parts, functions and disorders, as well as engineering medical solutions. By cultivating literacy practices as presented in this lesson, students can improve their scientific and technological literacy.

Subject:
Applied Science
Engineering
Life Science
Technology
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Jay Shah
Malinda Schaefer Zarske
Todd Curtis
Date Added:
09/18/2014
CAII helps tumor endothelial cells survive in a lactic acid-rich environment
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cancer cell growth depends on the production of new blood vessels by tumor endothelial cells in a process called angiogenesis. But the growing cancer cells produce large amounts of lactic acid as a byproduct of glucose breakdown. How tumor endothelial cells are able to survive in this toxic environment is unclear. In a recent study, researchers sought to uncover the mechanism of tumor endothelial cell survival in a lactic acid-rich tumor microenvironment. Using genetics and proteomics, they compared the RNA and protein levels of pH-regulating proteins in tumor endothelial cells to those in normal endothelial cells. They found that carbonic anhydrase 2 (CAII), an important pH regulator, was elevated in tumor endothelial cells, which was induced through the VEGF signaling pathway. Blocking CAII in tumor endothelial cells decreased cell survival in lactic acid conditions, and treating tumor-bearing mice with a CAII inhibitor had decreased lung metastasis..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/29/2020
The Cardiovascular System : Introduction to Blood Vessels (14:08)
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CC BY-ND
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This video kicks off the blood vessels series. The concepts covered in this video include:
-The functions of the cardiovascular system
-The components of the cardiovascular system
-The major divisions of the cardiovascular system: pulmonary circuit and systemic circuit

Lesson 8 in our Cardiovascular System (Heart and Blood Vessels) series. This is part of our Anatomy and Physiology lecture series.

If this video helps you please be sure to LST -like subscribe and tell your friends. Your support helps us make more videos. For the complete series please visit http://mrfordsclass.net/

Blood Videos
-Introduction to Blood (13:01): http://youtu.be/-Y5U49E-CM4
-Composition of Blood (13:02): http://youtu.be/YHCIMKZ0zrg
-Hematopoiesis-Making Blood (13:03): http://youtu.be/sibrcrXHJGI
-Red Blood Cells (13:04): http://youtu.be/19_6kUCVYfk

Heart and Blood Vessels Videos
-Heart Fundamentals (14:01): http://youtu.be/Y335KJ-EuDw
-Layers of the Heart (14:02): http://youtu.be/8PlwFTwJRMQ
-Chambers in the Heart (14:03): http://youtu.be/SdNQtPzUfHg
-Introduction to Blood Vessels (14:08): http://youtu.be/GVs8cd6jv94
-Types of Blood Vessels (14:09): http://youtu.be/_jkQR8v-bAg
-Movement of Blood (14:11): http://youtu.be/x9dH5TpKntk

Subject:
Anatomy/Physiology
Life Science
Material Type:
Lecture
Provider:
Mr. Ford's Class
Author:
Scott Ford
Date Added:
10/05/2014
The Cardiovascular System : Movement of Blood (14:11)
Only Sharing Permitted
CC BY-ND
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This videos looks at the three principles the control the functions of the cardiovascular system. We also look at blood flow, heart actions, blood volume, resistance to flow, blood viscosity and the hematocrit.

All of our videos can be found at http://www.mrfordsclass.net

The concepts covered in this video include:
-Blood flow
-Heart actions
-Blood volume
-Resistance to flow
-Blood viscosity
-Hematocrit

Lesson 11 in our Cardiovascular System (Heart and Blood Vessels) series. This is part of our Anatomy and Physiology lecture series.

If this video helps you please be sure to LST -like subscribe and tell your friends. Your support helps us make more videos. For the complete series please visit http://mrfordsclass.net/

Blood Videos
-Introduction to Blood (13:01): http://youtu.be/-Y5U49E-CM4
-Composition of Blood (13:02): http://youtu.be/YHCIMKZ0zrg
-Hematopoiesis-Making Blood (13:03): http://youtu.be/sibrcrXHJGI
-Red Blood Cells (13:04): http://youtu.be/19_6kUCVYfk

Heart and Blood Vessels Videos
-Heart Fundamentals (14:01): http://youtu.be/Y335KJ-EuDw
-Layers of the Heart (14:02): http://youtu.be/8PlwFTwJRMQ
-Chambers in the Heart (14:03): http://youtu.be/SdNQtPzUfHg
-Introduction to Blood Vessels (14:08): http://youtu.be/GVs8cd6jv94
-Types of Blood Vessels (14:09): http://youtu.be/_jkQR8v-bAg
-Movement of Blood (14:11): http://youtu.be/x9dH5TpKntk

Subject:
Anatomy/Physiology
Life Science
Material Type:
Lecture
Provider:
Mr. Ford's Class
Author:
Scott Ford
Date Added:
10/05/2014
The Cardiovascular System : Types of Blood Vessels (14:09)
Only Sharing Permitted
CC BY-ND
Rating
0.0 stars

This videos looks at the different types of blood vessels in the cardiovascular system.

The concepts covered in this video include:
•Types of blood vessels
•Arteries
•Arterioles
•Metarterioles
•Capillaries
•Venules
•Veins
•The tunics of the blood vessels
•Tunica Intima/Tunica Interna
•Tunica Media
•Tunica Adventitia/Tunica Externa

Lesson 9 in our Cardiovascular System (Heart and Blood Vessels) series. This is part of our Anatomy and Physiology lecture series.

If this video helps you please be sure to LST -like subscribe and tell your friends. Your support helps us make more videos. For the complete series please visit http://mrfordsclass.net/

Blood Videos
-Introduction to Blood (13:01): http://youtu.be/-Y5U49E-CM4
-Composition of Blood (13:02): http://youtu.be/YHCIMKZ0zrg
-Hematopoiesis-Making Blood (13:03): http://youtu.be/sibrcrXHJGI
-Red Blood Cells (13:04): http://youtu.be/19_6kUCVYfk

Heart and Blood Vessels Videos
-Heart Fundamentals (14:01): http://youtu.be/Y335KJ-EuDw
-Layers of the Heart (14:02): http://youtu.be/8PlwFTwJRMQ
-Chambers in the Heart (14:03): http://youtu.be/SdNQtPzUfHg
-Introduction to Blood Vessels (14:08): http://youtu.be/GVs8cd6jv94
-Types of Blood Vessels (14:09): http://youtu.be/_jkQR8v-bAg
-Movement of Blood (14:11): http://youtu.be/x9dH5TpKntk

Subject:
Anatomy/Physiology
Life Science
Material Type:
Lecture
Provider:
Mr. Ford's Class
Author:
Scott Ford
Date Added:
10/05/2014
Clearing a Path to the Heart
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Educational Use
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Following the steps of the engineering design process and acting as biomedical engineers, student teams use everyday materials to design and develop devices and approaches to unclog blood vessels. Through this open-ended design project, they learn about the circulatory system, biomedical engineering, and conditions that lead to heart attacks and strokes.

Subject:
Applied Science
Engineering
Health, Medicine and Nursing
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Jay Shah
Malinda Schaefer Zarske
Todd Curtis
Date Added:
10/14/2015
Computational model could help streamline angiogenesis-based therapies
Unrestricted Use
CC BY
Rating
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Angiogenesis, the formation of new blood vessels, is a popular target of various therapies. Some therapies, like those used in tissue engineering, are designed to promote angiogenesis and new tissue growth, while other therapies, such as those designed to fight cancer, aim to suppress angiogenesis— a lifeline for tumor cells. Unfortunately, these therapies aren’t always effective. Now, a new mathematical model could help researchers understand what molecular levers to pull to effectively modulate angiogenesis. Trained on published experimental data, the model predicted the effects of activating two common targets of angiogenesis-based therapies: vascular endothelial growth factor, or VEGF, and fibroblast growth factor, or FGF. Computational experiments showed that the two factors modify both the ERK signaling pathway, which is linked to cell proliferation, and the Akt signaling pathway, which is associated with cell survival and migration..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/03/2020
Exosomal miR-21-5p promotes blood vessel repair in atherosclerosis by regulating autophagy
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Atherosclerosis (AS), or thickening of the arteries due to plaque buildup, is a common and potentially deadly condition. A procedure called percutaneous transluminal coronary angioplasty (PTCA) has markedly improved patient survival, but narrowing of the arteries after PTCA (restenosis) remains a problem. Unique extracellular vesicles derived from endothelial colony-forming cells (ECFC-exosomes) are known to help repair injured vessels. Therefore, a new study explored the effects of ECFC-exosomes in a human cell model and a rat model of AS-/PTCA-induced vessel injury. In lipid-injured human vascular cells, ECFC-exosomes promoted repair-related processes such as cell proliferation, migration, and tube formation by enhancing autophagy, a process in which intracellular debris is degraded and recycled. Specifically, the exosomal miRNA miR-21-5p inhibited expression of the protein SIPA1L2 to increase autophagy..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/18/2022
Explanatory artificial intelligence improves the diagnosis of congenital heart defects before birth
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Congenital heart defects affect approximately 1% of all babies born each year and account for almost 20% of all newborn deaths. Early diagnosis while still in the womb can greatly improve an affected baby’s chance of survival. Unfortunately, diagnosis relies exclusively on ultrasound imaging, where accurate readings aren’t guaranteed. Researchers in Japan are tackling this problem by enlisting the help of artificial intelligence. More importantly, they’re helping the doctors entrusted with patient care to understand how AI programs spot heart defects. Advancements in artificial intelligence have improved how congenital heart defects are diagnosed. Ultrasound videos of fetal hearts beating normally and others with structural defects can be studied with AI, which can then determine whether the fetal hearts in new videos are abnormal or not..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Computer Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
01/31/2023
Let the Blood Flow
Read the Fine Print
Educational Use
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Students work as biomedical engineers to find liquid solutions that can clear away polyvinyl acetate polymer "blood clots" in model arteries (made of clear, flexible tubing). Teams create samples of the "blood clot" polymer with different concentrations to discover the concentration of the model clot and then test a variety of liquids to determine which most effectively breaks down the model blood clot. Students learn the importance of the testing phase in the engineering design process, because they are only given one chance to present the team's solution and apply it to the model blood clot.

Subject:
Applied Science
Education
Engineering
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Ann McCabe
Azim Laiwalla
Carleigh Samson
Date Added:
09/18/2014
Potential roles of angiogenesis inhibitors in cancer treatment
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Tumor growth relies upon the production of new blood vessels, also known as angiogenesis, to supply adequate oxygen and nutrients to the cells. Angiogenesis blockade therapy was thus developed to impair blood vessel growth and cut off this supply. This is accomplished with the use of medicines targeting pro-angiogenic factors such as vascular-endothelium growth factor (VEGF), fibroblast growth factor (FGF), and stem cell factor (SCF). For example, bevacizumab is a monoclonal antibody that targets VEGF and has shown promise in combating non-small-cell lung cancer, but the use of angiogenesis inhibitors has also been linked to an increase in local tumor invasiveness and the spread of cancer to other parts of the body. New evidence suggests that these issues can be diminished by administering anti-angiogenic agents in combination with other strategies..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/18/2022
Put Your Heart into Engineering
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Educational Use
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This lesson contains background about the blood vascular system and the heart. Also, the different sizes of capillaries, veins, and arteries, and how they affect blood flow through the system. We will then proceed to talk about the heart's function in the blood vascular system. This will lead into a discussion of heart valves, how they work and what might cause them to fail. Then we will discuss prosthetic heart valves.

Subject:
Anatomy/Physiology
Applied Science
Engineering
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Alice Hammer
Date Added:
09/18/2014
A painless, radiation-free approach for looking at blood vessels
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Physicians may soon be able to get a detailed look at blood vessels surrounding breast tumors quickly, painlessly, and without radiation, thanks to the work of a team of Japanese researchers. One application of the technology is earlier and more accurate tracking of when cancer has turned deadly. The formation of new blood vessels around a tumor is a key sign that cancer is getting ready to spread. But getting a clear look at these blood vessels can be tricky. Approaches like MRI or computed tomography often come with a hefty price tag, and exposure to contrast agent or radiation may pose health risks. To sidestep these issues, the researchers optimized a way to perform photoacoustic imaging. This type of imaging utilizes the light-absorbing properties of hemoglobin to show where blood is flowing in the body. When hemoglobin is exposed to pulses of laser light, it produces small vibrations. These vibrations are picked up by scanners and used to generate a detailed map of blood vessel architecture..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Anatomy/Physiology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/23/2019