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100th Day of School Activities
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Resources to mark the 100th day of school with math activities. Challenge students to generate 100 different ways to represent the number 100. Students will easily generate 99 + 1 and 50 + 50, but encourage them to think out of the box. Challenge them to include examples from all of the NCTM Standards strands: number sense, numerical operations, geometry, measurement, algebra, patterns, data analysis, probability, discrete math, Create a class list to record the best entries. Some teachers write 100 in big bubble numeral style and then record the entries inside the numerals.

Subject:
Mathematics
Material Type:
Activity/Lab
Provider:
Mathwire
Author:
Terry Kawas
Date Added:
02/16/2011
ATP: The Fuel of Life
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The goal of this lesson is to introduce students who are interested in human biology and biochemistry to the subtleties of energy metabolism (typically not presented in standard biology and biochemistry textbooks) through the lens of ATP as the primary energy currency of the cell. Avoiding the details of the major pathways of energy production (such as glycolysis, the citric acid cycle, and oxidative phosphorylation), this lesson is focused exclusively on ATP, which is truly the fuel of life. Starting with the discovery and history of ATP, this lesson will walk the students through 8 segments (outlined below) interspersed by 7 in-class challenge questions and activities, to the final step of ATP production by the ATP synthase, an amazing molecular machine. A basic understanding of the components and subcellular organization (e.g. organelles, membranes, etc.) and chemical foundation (e.g. biomolecules, chemical equilibrium, biochemical energetics, etc.) of a eukaryotic cell is a desired prerequisite, but it is not a must. Through interactive in-class activities, this lesson is designed to spark the students’ interest in biochemistry and human biology as a whole, but could serve as an introductory lesson to teaching advanced concepts of metabolism and bioenergetics in high school depending on the local science curriculum. No supplies or materials are needed.

Subject:
Life Science
Biology
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Christian Schubert
Date Added:
02/13/2015
Acid Stomach
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This Science NetLinks lesson is intended for a high-school, introductory chemistry class or health class. The lesson begins with an article on the history of the development of aspirin. Students will then complete a lab that compares the reaction of regular aspirin, buffered aspirin, and enteric aspirin in neutral, acidic, and basic solutions. They will then analyze the results of the experiment to gain insight into how this information was used by researchers to solve some of the problems associated with aspirin. To complete the lesson, students must understand acids and bases.

Subject:
Anatomy/Physiology
Biology
Chemistry
Material Type:
Lesson Plan
Teaching/Learning Strategy
Provider:
AAAS
Provider Set:
Science Netlinks
Date Added:
08/08/2007
Acids, pH, and Buffers: Some Basic Chemistry for Biological Science
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In this "clicker case," a three-year-old girl gets into the medicine cabinet and ingests an unknown number of aspirin tablets. Her brother calls 911 and the girl is taken to a nearby hospital, where she is treated. The case is used to discuss the Law of Mass Action, chemical equilibrium and equilibrium constants, pH, and weak acids and buffers in the context of medical management of a life-threatening emergency. It is called a "clicker" case because it is designed to be presented in a class that uses personal response systems, or "clickers." The case is presented via a series of PowerPoint slides (~400KB) punctuated by multiple-choice questions, which the students answer using their clickers. It could be adapted for use without these technologies. The case is suitable for use in an introductory biology course where integration with biologically relevant chemistry is an important course objective. It could also be used in a chemistry course.

Subject:
Life Science
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Terry Platt
Date Added:
01/01/2010
An Adventure in Stereochemistry: Alice in Mirror Image Land
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Playfully alluding to Lewis Carroll's tale of Alice Through the Looking Glass, this case study considers the problems that would arise if a person were to cross over into a mirror-image environment. Students read about a drowsy undergraduate studying for a stereochemistry exam who finds herself in a place where spearmint gum tastes like caraway seed. The case emphasizes the lock-and-key theory of enzyme action and stresses the need for molecules to have the proper chirality if they are to be biologically useful. Designed for introductory organic chemistry and biochemistry courses, the case could also be used in biology courses.

Subject:
Life Science
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Frank J. Dinan
Gordon T. Yee
Date Added:
01/01/2004
Alternative Fuels from Biomass Sources
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Is climate change real? Yes, it is! And technologies to reduce Greenhouse Gas (GHG) emissions are being developed. One type of technology that is imperative in the short run is biofuels; however, biofuels must meet specifications for gasoline, diesel, and jet fuel, or catastrophic damage could occur. This course will examine the chemistry of technologies of bio-based sources for power generation and transportation fuels. We'll consider various biomasses that can be utilized for fuel generation, understand the processes necessary for biomass processing, explore biorefining, and analyze how biofuels can be used in current fuel infrastructure.

Subject:
Chemistry
Material Type:
Full Course
Provider:
Penn State's College of Earth and Mineral Sciences (http
Penn State University
Provider Set:
// e-education.psu.edu/oer/)
Author:
Caroline Clifford
Date Added:
10/07/2019
Amanda's Absence: Should Vioxx Be Kept Off the Market?
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When chronic pain forces a top student to withdraw from college, biology instructor Dr. Sharpe learns that medications (in this case, Vioxx) may be removed from the market for many reasons, including safety concerns. As the case unfolds, students learn how the FDA balances drug safety against medical needs. As written, the case is appropriate for a non-majors biology course. It could also be adapted for use in a more advanced course in cell biology, pharmacology, or biochemistry, or modified to explore statistical analysis, specific analytical methods used for risk/benefit analysis, or bioethical issues.

Subject:
Life Science
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Dan Johnson
Date Added:
01/01/2005
Analysis of Biological Networks (BE.440), Fall 2004
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This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be studied include chemotaxis, the fixation of nitrogen into organic biological molecules, growth factor and hormone mediated signaling cascades, and signaling cascades leading to cell death in response to DNA damage. In each case, the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. The course examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular/cellular/tissue/organ-level functions. Chemical and quantitative views of the interplay of multiple pathways as biological networks are emphasized. Student work will culminate in the preparation of a unique grant application in an area of biological networks.

Subject:
Biology
Chemistry
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Essigmann, John
Sasisekharan, Ram
Date Added:
01/01/2004
Another Can of Bull?  Do Energy Drinks Really Provide a Source of Energy?
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This case is a "clicker" adaptation of a similarly titled case by Merle Heidemann and Gerald Urquhart of Michigan State University, "A Can of Bull?" The story introduces students to basic principles of metabolism and energy through a biochemical analysis of commonly available "energy drinks" that many students purchase at relatively high prices. Students learn to define energy in a biological/nutritional context, identify valid biochemical sources of energy, discuss how foods are metabolized to generate ATP, and critically evaluate marketing claims for various energy drinks. The case can be used in introductory level courses to introduce these principles or as a review of basic biochemistry and nutrition for upper-level students in nutrition, physiology, or biochemistry courses. The case is presented in class using a PowerPoint (~2.3MB) that is punctuated by multiple-choice questions students answer using personal response systems, or "clickers."

Subject:
Life Science
Anatomy/Physiology
Nutrition
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Cheryl D. Davis
Nancy A. Rice
Date Added:
01/01/2009
Bad Fish, Bad Bird: Neurotoxin Poisoning from Fish and Fowl
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This "clicker case" is based on the General Biology edition of James Hewlett's "Bad Fish" case in our collection. The case follows the story of biologist Dr. Westwood, who is accidentally poisoned, first while traveling in Asia and then in the South Pacific. Students learn about Dr. Westwood's experiences and about nerve cell physiology-focusing especially on the role of ion channels in maintaining and changing electrical gradients across the cell membrane (resting potential and action potentials). They then apply what they learn in each part of the case to determine the mechanism of neurotoxin poisonings described in the case. The case is presented in class via PowerPoint (~2MB). Students use personal response systems, or "clickers," to answer the multiple-choice questions that punctuate the PowerPoint presentation as they explore the underlying mechanism of Dr. Westwood's poisoning.

Subject:
Life Science
Anatomy/Physiology
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Kristina Hannam
Date Added:
01/01/2010
Bad Fish: General Biology Edition
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In this version, developed for a course in general biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. The General Biology Edition is designed for an introductory biology course. Its basic storyline and core objectives are carried over into a Human Anatomy& Physiology Edition and a Cell& Molecular Biology Edition, also in our collection, each of which has its own set of questions.

Subject:
Life Science
Anatomy/Physiology
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
James A. Hewlett
Date Added:
01/01/2003
Bilirubin: E-/Z-, But Not Easy
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In this case study, two students meet a professor who surprises them by telling them that a biochemically important molecule's structure has been incorrectly represented in the published literature - in an article in the Proceedings of the National Academy of Sciences, a major biochemistry textbook, and even The Merck Index. The students are challenged to find the nature of the structural errors and correct them. In addition to demonstrating that the technical literature is not without its flaws, the case reviews important concepts related to geometric isomerism and tautomerism.

Subject:
Life Science
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Frank J. Dinan
Date Added:
01/01/2003
Biochemical Engineering, Spring 2005
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This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism are also covered. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.

Subject:
Biology
Chemistry
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Prather, Kristala
Date Added:
01/01/2005
Biochemistry
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Biochemistry is the study of the chemical processes and compounds, such as cellular makeup, that bring about life in organisms. This course will look at how these formed biomolecules interact and produce many of life's necessary processes. Also it will look at the most commonly used techniques in biochemistry research. Upon successful completion of this course, students will be able to: recognize and describe the structure of the following basic biomolecules: nucleic acids, amino acids, lipids, carbohydrates; diagram how these basic biomolecules are used as building blocks for more complex biomolecules; differentiate between reactions that create biomolecules; describe how these biomolecules are used in specific cellular pathways and processes; analyze how feedback from one pathway influences other pathways; explain how energy is utilized by a cell; indicate how biomolecules and pathways are regulated; describe how enzymes play a key role in catalysis; assess which biochemical technique should be used to study a given biochemical problem. (Biology 401; See also: Chemistry 109)

Subject:
Biology
Chemistry
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
11/16/2011
Biochemistry
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This is an introductory course in biochemistry, designed for both biology and chemical engineering majors.

A consistent theme in this course is the development of a quantitative understanding of the interactions of biological molecules from a structural, thermodynamic, and molecular dynamic point of view. A molecular simulation environment provides the opportunity for you to explore the effect of molecular interactions on the biochemical properties of systems. Topics covered include: Protein Function, Structure and Function of Carbohydrates, Lipids and Biological Membranes, Metabolism, Nucleic and Acid and Biochemistry.

Subject:
Chemistry
Material Type:
Diagram/Illustration
Full Course
Interactive
Reading
Provider:
Carnegie Mellon University
Provider Set:
Open Learning Initiative
Date Added:
01/09/2013
Biochemistry Laboratory Manual For Undergraduates
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Biochemistry laboratory manual for undergraduates – an inquiry based approach by Gerczei and Pattison is the first textbook on the market that uses a highly relevant model, antibiotic resistance, to teach seminal topics of biochemistry and molecular biology while incorporating the blossoming field of bioinformatics. The novelty of this manual is the incorporation of a student-driven real real-life research project into the undergraduate curriculum. Since students test their own mutant design, even the most experienced students remain engaged with the process, while the less experienced ones get their first taste of biochemistry research. Inclusion of a research project does not entail a limitation: this manual includes all classic biochemistry techniques such as HPLC or enzyme kinetics and is complete with numerous problem sets relating to each topic.

Subject:
Life Science
Material Type:
Textbook
Provider:
De Gruyter
Author:
Scott Pattison
Timea Gerczei-Fernandez
Date Added:
12/01/2014
Biochemistry Laboratory, Spring 2009
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" The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format. Acknowledgments Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan."

Subject:
Chemistry
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Taylor, Elizabeth Vogel
Date Added:
01/01/2009
Bioinorganic Chemistry
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Exploration of the biological importance of inorganic complexes. Topics include: biochemistry and transition metal chemistry review, characterization methods, metal ion transport and cellular storage, biological electron transfer, the nitrogen cycle, oxygen transport and transfer, oxygen processing, and enzymes and proteins.

Subject:
Chemistry
Material Type:
Full Course
Provider:
The Saylor Foundation
Date Added:
08/28/2013
Biological Terrorism: The Anthrax Scare of 2001
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In the weeks following the September 11, 2001, terrorist attacks on the World Trade Center and the Pentagon, anthrax-laced envelopes were mailed to individuals in government and the news media. Thousands were treated for exposure, and five people were killed. At the same time, scientists solved the last remaining pieces of the anthrax puzzle and the mechanism of infection of the anthrax toxin is now well understood. Developed for a second-semester biochemistry course, this case presents students with a wealth of biochemical, microbiological, and immunological material to analyze. It also explores important societal issues related to national preparedness against bioterrorist attacks, funding for biodefense research, and the use and misuse of antibiotic therapy.

Subject:
Life Science
Chemistry
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Kathleen A. Cornely
Date Added:
01/01/2005