The goal of this lesson is to introduce students who are interested in human biology and biochemistry to the subtleties of energy metabolism (typically not presented in standard biology and biochemistry textbooks) through the lens of ATP as the primary energy currency of the cell. Avoiding the details of the major pathways of energy production (such as glycolysis, the citric acid cycle, and oxidative phosphorylation), this lesson is focused exclusively on ATP, which is truly the fuel of life. Starting with the discovery and history of ATP, this lesson will walk the students through 8 segments (outlined below) interspersed by 7 in-class challenge questions and activities, to the final step of ATP production by the ATP synthase, an amazing molecular machine. A basic understanding of the components and subcellular organization (e.g. organelles, membranes, etc.) and chemical foundation (e.g. biomolecules, chemical equilibrium, biochemical energetics, etc.) of a eukaryotic cell is a desired prerequisite, but it is not a must. Through interactive in-class activities, this lesson is designed to spark the students’ interest in biochemistry and human biology as a whole, but could serve as an introductory lesson to teaching advanced concepts of metabolism and bioenergetics in high school depending on the local science curriculum. No supplies or materials are needed.

ATP synthase and its role in mitochondria during respiration and chloroplasts during photosynthesis.

Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Discuss the importance of electrons in the transfer of energy in living systemsExplain how ATP is used by the cell as an energy source

By the end of this section, you will be able to:Discuss the importance of electrons in the transfer of energy in living systemsExplain how ATP is used by the cell as an energy source

By the end of this section, you will be able to:Explain the role of ATP as the cellular energy currencyDescribe how energy is released through hydrolysis of ATP

By the end of this section, you will be able to:Explain the role of ATP as the cellular energy currencyDescribe how energy is released through hydrolysis of ATP

By the end of this section, you will be able to:Explain how plants absorb energy from sunlightDescribe short and long wavelengths of lightDescribe how and where photosynthesis takes place within a plant

By the end of this section, you will be able to:Explain how plants absorb energy from sunlightDescribe short and long wavelengths of lightDescribe how and where photosynthesis takes place within a plant

These lecture slides contain open with a scenario, and chapter images, lecture outlines, and brief conceptual overviews. The slides were based on the OpenStax image slides and were developed by Asha Rao, Matthew Aderholt, and Veronica Amaku.

How oxidation of co-enzymes like NADH can lead to the production of ATP through oxidative phosphorylation.

Students learn about the basic principles of electromicrobiology—the study of microorganisms’ electrical properties—and the potential that these microorganisms may have as a next-generation source of sustainable energy. They are introduced to one such promising source: microbial fuel cells (MFCs). Using the metabolisms of microbes to generate electrical current, MFCs can harvest bioelectricity, or energy, from the processes of photosynthesis and cellular respiration. Students learn about the basics of MFCs and how they function as well as the chemical processes of photosynthesis and cellular respiration