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High-dose saccharin does not induce gut microbiota changes or glucose intolerance
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Non-caloric artificial sweeteners (NCAS) are widely used as a substitute for dietary sugars to control body weight or glycemia. With a drastic increase in their use recently, health officials have been concerned about the effects of NCAS use. Epidemiological studies have had conflicting results, with some studies suggesting that NCAS can alter the gut microbiota or induce glucose intolerance. A new clinical study explored the effects of pure saccharin on the gut microbiota and glucose tolerance in healthy individuals. In a double-blind, placebo-controlled, parallel arm study involving men and women, researchers found that the maximum acceptable daily intake of saccharin, lactisole, or saccharin with lactisole did not alter microbial diversity or oral glucose tolerance. A parallel study with healthy mice had similar results, with no treatment altering microbial diversity, glucose absorption, or microbial activity..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
03/11/2021