This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Research has identified remarkably effective treatments for breast cancer But translation of these results to all patients requires pharmacogenetic research using diverse patient populations Although tamoxifen has been used to reduce the risk of breast cancer recurrence for the past 40 years Little is known about how well the drug works in American Indian and Alaska Native (AIAN) people A recent study focused on genetic variants of the cytochrome P450 gene CYP2D6, which is critical for tamoxifen activation Looking at AIAN participants in Alaska and Montana they identified common CYP2D6 variants in these populations that may affect tamoxifen metabolism Patients with these variants may not respond well to tamoxifen treatment and may benefit from alternative therapies This study highlights the key role of CYP2D6-mediated metabolism in tamoxifen response and suggests that considering genetic variation in diverse populations can help to improve the efficacy of breast cancer treatment We thank women from the Confed.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

A unique perspective on the confluence of the three basic conceptual frameworks in human experience. Contains several studies, with data, of remarkable world views of disparate cultures based on their specific cultures language. The premise is that how people experience the world, then think about it, then create a language around it, alters their perception of the world in very fundamental ways. The radical notion is that thought and language, creates the circumstances of, and contribute to significantly different realities for different peoples.

The internalization and realization of this concept is significant and can possibly radically alter and change how different cultures assess their ability to, at the most basic levels, understand other cultures realities.

A curriculum unit of three lessons in which students explore Hopi place names, poetry, song, and traditional dance to better understand the ways Hopi people connect with the land and environment through language. The unit is centered on the practice of growing corn. Students make inferences about language, place, and culture and also look closely at their own home environment and landscape to understand the places, language, and songs that give meaning to cultures and communities

A guided exploration of "Hopitutskwa," the Hopi homeland, through maps and place names. Using English translations, students make inferences about the Hopi cultural relationship to landscape and place. They examine regional place names of their own home communities and create personal maps by identifying and naming places of importance in their lives.

An exploration of the symbolism and imagery of corn and environment as manifested in Hopi song and traditional dances. Students analyze examples of historical and contemporary Hopi song and examine images of Hopi dance in order to expand cultural awareness.

Recently, you may have noticed a lot of big news coming out of Indigenous America, from protests at Standing Rock to the return of wild bison to efforts to bring home ancestral remains and artifacts. But when you talk to the movers and shakers, the conversation often comes back around to a bitter history – the Plains Indian Wars. In Season 6 of the Modern West Podcast, we hear the story from the point of view of the Plains tribes themselves. We discover how raw that story still is, and yet how communities are coming together to heal it.

This lesson discusses the differences between common representations of Native Americans within the U.S. and a more differentiated view of historical and contemporary cultures of five American Indian tribes living in different geographical areas. Students will learn about customs and traditions such as housing, agriculture, and ceremonial dress for the Tlingit, Dinè, Lakota, Muscogee, and Iroquois peoples.

Native American groups had to choose the loyalist or patriot cause"”or somehow maintain a neutral stance during the Revolutionary War. Students will analyze maps, treaties, congressional records, first-hand accounts, and correspondence to determine the different roles assumed by Native Americans in the American Revolution and understand why the various groups formed the alliances they did.

Students study the interaction between environment and culture as they learn about three vastly different indigenous groups in a game-like activity that uses vintage photographs, traditional stories, photos of artifacts, and recipes.

In this lesson, students explore issues of culture and identity and learn about Navajo culture by examining the perspectives of those portrayed in the film, Return of Navajo Boy.