Online problems by Yun Zhang for use with: College Physics, by senior contributing authors, Paul Peter Urone, Roger Hinrichs, and contributing authors, Kim Dirks, Manjula Sharma. College Physics is available in OpenStax at https://openstax.org/details/books/college-physics?Book%20details.

For instructors: These problems are implemented dynamically on the Varafy Online platform, with randomized variables and instant feedback to users. Instructors can do the following to use them for online assignments: 1) set up an account in Varafy; 2) ask Varavy to share the problems. (June 10, 2020)

Table of Contents
-- OpenStax link and instructions
-- Problem: !D kinematics
-- Problem: Free fall and projectile motions
-- Problem: Vectors
-- Problem: Newton's laws circular motion and gravitation
-- Problem: Work and energy
-- Problem: Momentum and collisions
-- Problem: Fluid statics.

(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

A previously healthy 43-year-old woman first suffered from headache with dizziness, vomiting, and nausea beginning 5 months before hospital admission. CT scans showed subarachnoid hemorrhage involving the right temporal and occipital lobes, while MRI revealed abnormal signals in the left thalamus and right temporal-occipital lobes. Five months later she suffered from headache, transient unconsciousness and aggravated left upper-limb paralysis. This time, neurological examinations revealed a decrease in power and deep tendon reflexes of the left upper limb. The activated partial thromboplastin time was notably prolonged at 38.8s, while the prothrombin time was normal. Cerebrospinal fluid (CSF) contained 100 erythrocytes /mm3. Neuroimaging revealed infarcts and hemorrhages in bilateral frontal lobes (Fig. 1a) and slit-like complex softening of the right temporal-occipital lobes (Fig. 1b). MRI showed diffuse enhancement in the dural mater and sulci of bilateral frontal-parietal lobes and tentorium (Fig. 1b).MR venography disclosed occlusions in the right transverse and sigmoid sinus, suggesting thrombosis (Fig. 1c). Five days after admission, the patient died and a restricted cranial autopsy was performed.

Metastatic disease is responsible for the vast majority of deaths associated with cancer, yet our understanding of how metastases arise is still developing. In this course, we will introduce various concepts and models that have been proposed to explain how cancer cells disseminate from a primary tumor to distant anatomical sites. We’ll learn about the critical factors that influence cancer metastasis frontiers through analysis and discussion of relevant primary research articles, with an emphasis on mechanisms of metastasis that can be applied across different cancer types. Students will gain a broad understanding of the field of cancer metastasis, including state-of-the-art techniques that are being used to address pressing questions in the field.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.