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Extracting DNA
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This lesson for students in grades 9-12 introduces DNA, genes, chromosomes, the ...

This lesson for students in grades 9-12 introduces DNA, genes, chromosomes, the chemicals that make up DNA. After the basic information, students will do an experiment in which they will separate out DNA from peas. Knowing that DNA can be separated will give them a base of understanding for future lessons in biology, evolution, biotechnology, and health technology.

Subject:
Biology
Genetics
Material Type:
Lesson Plan
Teaching/Learning Strategy
Provider:
AAAS
Provider Set:
Science Netlinks
A Family in Need: In-Class Case Study on Cancer Genetics
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“A Family in Need” was designed as an in-class problem-based learning activity ...

“A Family in Need” was designed as an in-class problem-based learning activity for students to learn about several innovative medical applications of molecular biology. Students assume the role of a second-year medical student assigned to work with a pediatric oncologist who has just biopsied a tumor-like growth in the adrenal gland of her 17-year-old patient, Lee F. After taking Lee’s family history and performing a pedigree analysis, students review clinical and genetic characteristics of several syndromes associated with adrenal cancer. Students then explore various diagnostic and biomedical research techniques such as PCR, DNA sequencing, and pre-implantation genetic diagnosis. The case concludes with a consideration of how to treat Lee’s condition with the help of gene cloning and the potential of gene therapy. Although originally written for an upper-level college genetics course, the case could also be adapted for an introductory molecular/cellular biology course, a non-majors biology course, or a professional school medical genetics course.

Subject:
Genetics
Material Type:
Case Study
Lecture Notes
Unit of Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Gene Expression During Development: Experimental Design Problem
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This problem challenges students to design experiments using techniques measuring gene expression ...

This problem challenges students to design experiments using techniques measuring gene expression (reverse transcriptase PCR, microarrays, in situ hybridization).

Subject:
Education
Life Science
Genetics
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Starting Point (SERC)
Author:
Debby Walser-Kuntz
Sarah Deel
Susan Singer
General Biology I
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An integrated course stressing the principles of biology. Life processes are examined ...

An integrated course stressing the principles of biology. Life processes are examined primarily at the molecular and cellular levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

Subject:
Biology
Genetics
Chemistry
Material Type:
Activity/Lab
Full Course
Lecture Notes
Syllabus
Provider:
UMass Boston
Provider Set:
UMass Boston OpenCourseWare
Author:
Ph.D.
Professor Brian White
Genetic Drift
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In this biology simulation, students use a mathematical simulation of genetic drift ...

In this biology simulation, students use a mathematical simulation of genetic drift to answer questions about the factors that influence this evolutionary process. Students run a series of simulations varying allele frequency and population size and then analyze their data and propose a model to explain their results.

Subject:
Education
Life Science
Mathematics
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Starting Point: Teaching Entry Level Geoscience
Author:
Scott Cooper
Genetics Book List
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This OLogy reference list has seven kid-friendly books on genetics. A short ...

This OLogy reference list has seven kid-friendly books on genetics. A short description is given for each title, along with author name and publisher. The list includes: illustrated looks at cells, genes, and DNA, hands-on activities and solve-it-yourself mysteries, and easy-to-understand and thought-provoking explorations of cloning and genetic engineering.

Subject:
Biology
Genetics
Material Type:
Reading
Provider:
American Museum of Natural History
Provider Set:
American Museum of Natural History
A Genetics Lab in a Very Unusual Place
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This online article, from the museum's Musings newsletter for educators, looks at ...

This online article, from the museum's Musings newsletter for educators, looks at the fully functional Genetics Laboratory that was part of the exhibition The Genomic Revolution. It discusses: the significance of the recent sequencing of the human genome in a historical perspective the process visitors underwent during their hour-and-a-half visit to the lab, where they extracted, isolated, visualized, and sequenced their DNA the follow-up activities for visitors on the AMNH Web site.

Subject:
Biology
Genetics
Material Type:
Teaching/Learning Strategy
Provider:
American Museum of Natural History
Provider Set:
American Museum of Natural History
Genomic DNA Isolation From Human Cheek Cells
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In this lab activity students isolate genomic DNA from their cheek cells ...

In this lab activity students isolate genomic DNA from their cheek cells on the inside of their mouths. Students then remove the DNA from those cheek cells. It shows the DNA is in every cell in the body and can be extracted easily. Students use their DNA necklace which they proudly wear around school the rest of the day.

Subject:
Education
Life Science
Material Type:
Activity/Lab
Assessment
Lesson Plan
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Guthmiller, Jim
Jim Guthmiller
Gleevec and the Cell Cycle Problem
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Students are given a problem about a relatively new treatment for cancer, ...

Students are given a problem about a relatively new treatment for cancer, Gleevec, and asked to apply and synthesize what they have learned about cell signaling and the eukaryotic cell cycle to explain why this targeted treatment works to prevent cell division with fewer side effects than traditional chemotherapeutic agents.

Subject:
Education
Life Science
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Starting Point (SERC)
Author:
Debby Walser-Kuntz
Sarah Deel
Susan Singer
Golden Rice: An Intimate Debate Case
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In this intimate debate case, students consider whether to support the development ...

In this intimate debate case, students consider whether to support the development and use of Golden Rice as a means to alleviate vitamin A deficiency in the developing world. Since many of the arguments typically raised against genetically modified organisms (GMOs) do not apply to this particular GM crop, students are forced to analyze the facts rather than rely on what they have heard in the media. Developed for an introductory molecular biology undergraduate course, the case could also be used at more senior levels.

Subject:
Education
Life Science
Ecology
Forestry and Agriculture
Nutrition
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Annie PrudĽË_homme Genereux
How Enzymes Work: Investigating Their Specificity and Susceptibility to Environmental Factors Using Jell-O
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This activity is a lab investigation in which students design and conduct ...

This activity is a lab investigation in which students design and conduct experiments using pineapple juice containing the enzyme bromelain and its affect on the substrate gelatin found in Jell-O. The focus of student driven investigations are on enzyme specificity, activity and the impact of environmental factors on enzyme functioning. Based on the original activities from School Improvement in Maryland; "Pineapple/Jell-O Lab," Access Excellence Activities Exchange; "Enzyme Labs Using Jell-O" by Anne McDonald and Michael O'Hare, and AP & Regents Biology; "Lab 8: Pineapple Enzymes and Jell-O Molds" by Kim B. Foglia.

Subject:
Education
Life Science
Biology
Material Type:
Activity/Lab
Assessment
Lesson Plan
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Heather Netland, Jefferson High School, Alexandria, MN, based on the original activities from School Improvement in Maryland; "Pineapple/Jell-O Lab," Access Excellence Activities Exchange; "Enzyme Labs Using Jell-O" by Anne McDonald and Michael O'Hare, and AP & Regents Biology; "Lab 8: Pineapple Enzymes and Jell-O Molds" by Kim B. Foglia.
Netland, Heather
Introduction to Molecular and Cellular Biology
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Though biology as we know it today is a relatively new field, ...

Though biology as we know it today is a relatively new field, we have been studying living things since the beginning of recorded history. This introductory course in biology starts at the microscopic level, with molecules and cells, then moves into the specifics of cell structure and behavior. Upon successful completion of this course, students will be able to: Describe in general terms how life began on Earth; Identify early scientists that played important roles in furthering our understanding of cellular life; Describe the characteristics that define life; List the inorganic and organic molecules that are necessary for life; List the structure and function of organelles in animal and plant cells; List the similarities and differences between animal and plant cells; Describe the reactions in photosynthesis; Explain how the different photosynthetic reactions are found in different parts of the chloroplast; Describe the sequence of photosynthetic reactions; Explain the use of products and the synthesis of reactants in photosynthesis; Explain how protein is synthesized in eukaryotic cells; Describe the similarities and differences between photosynthesis and aerobic respiration; List the reactions in aerobic respiration; Explain the use of products and the synthesis of reactants in aerobic respiration; Describe the similarities and differences between anaerobic and aerobic respiration. (Biology 101; See also: Psychology 203)

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
The Saylor Foundation
Introduction to Molecular and Cellular Biology - Laboratory
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This lab course supplements Introduction to Molecular and Cellular Biology. Although it ...

This lab course supplements Introduction to Molecular and Cellular Biology. Although it does not replicate a true lab experience, it does enable further exploration of some key principles of molecular and cellular biology. In each unit, the student will work through tutorials related to important scientific concepts, and then will be asked to think creatively about how those concepts can be put to practical or experimental use. This lab course also contains activities devoted to learning important techniques in scientific study such as microscope use, DNA extraction, Polymerase Chain Reaction, and examination of DNA microarrays. Upon successful completion of this lab supplement, students will be able to: Identify the important components of scientific experiments and create their own experiments; Identify the molecular differences between proteins, fats, and carbohydrates, and explain the molecular behavior of water; Describe the process of photosynthesis; Describe the process of cellular respiration; Identify the differences between DNA and RNA; Describe the entire transcription/translation process, from gene to protein; Explain how recombinant genomes are formed; Use critical thinking to find ways that any of the above natural processes might be altered or manipulated; Explain how to use a compound light microscope for data collection; Explain how to conduct and use various experimental techniques, including DNA extraction, PCR, and DNA microarrays. (Biology 101 Laboratory)

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
The Saylor Foundation
Investigating Characteristics of Enzymes and the Factors That Affect Their Function
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This classroom lab allows students to develop skills of the scientific method ...

This classroom lab allows students to develop skills of the scientific method while exploring the characteristics of enzymes.

Subject:
Education
Life Science
Chemistry
Material Type:
Activity/Lab
Assessment
Lesson Plan
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Jen Vance
Vance, Jen
Investigating Starch in Foods
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This activity is a classroom experiment where students gather data on which ...

This activity is a classroom experiment where students gather data on which foods contain starch. They use observation and develop their own hypothesis to create a question they would like to discover about starches.

Subject:
Life Science
Nutrition
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Darlene Schleis
Kimball's Biology Pages
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No Strings Attached
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The pages represent an online biology textbook created by Professor John W. ...

The pages represent an online biology textbook created by Professor John W. Kimball who taught at Harvard, Tufts, and Phillips Andover Academy before he retired. He now maintains this free biology book, constantly updated and set up for easy browsing and searching.

Subject:
Biology
Material Type:
Textbook
Provider:
Kimball's Biology Pages
Author:
John W. Kimball
Living With Her Genes: Early Onset Familial Alzheimer's Disease
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When a 30-year-old genetic counselor learns that her 38-year-old sister has developed ...

When a 30-year-old genetic counselor learns that her 38-year-old sister has developed early onset familial Alzheimer's disease (EOFAD), a dominantly inherited disorder that led to their father's death at age 42, she struggles with whether to undergo genetic testing and whether to have children. This interrupted case study examines the impact of genetic testing on people and their families when there is no treatment or cure for a disease. It covers principles of Mendelian inheritance as well as genetic and reproductive technologies ,such as gene tests, pre-implantation genetic diagnosis, and in vitro fertilization. It can be used in introductory biology courses for both majors and non-majors or adapted for more advanced courses in genetics and molecular biology.

Subject:
Life Science
Material Type:
Case Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Author:
Alice M. Stanford
Deborah D. Wygal
Lynne H. Gildensoph