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How DNA Binding Proteins Recognize Their Target Sequences in DNA
Unrestricted Use
CC BY
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Instructional video on how DNA binding proteins recognize their target sequences in DNA.

Although textbooks describe this process and show illustrations, it is difficult to grasp without seeing a live demonstration.

Created for Biology 41 General Genetics at Tufts University.

Subject:
Biology
Genetics
Life Science
Material Type:
Simulation
Author:
Ekaterina V. Mirkin
Date Added:
06/02/2021
How Enzymes Work: Investigating Their Specificity and Susceptibility to Environmental Factors Using Jell-O
Conditional Remix & Share Permitted
CC BY-NC-SA
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This activity is a lab investigation in which students design and conduct experiments using pineapple juice containing the enzyme bromelain and its affect on the substrate gelatin found in Jell-O. The focus of student driven investigations are on enzyme specificity, activity and the impact of environmental factors on enzyme functioning. Based on the original activities from School Improvement in Maryland; "Pineapple/Jell-O Lab," Access Excellence Activities Exchange; "Enzyme Labs Using Jell-O" by Anne McDonald and Michael O'Hare, and AP & Regents Biology; "Lab 8: Pineapple Enzymes and Jell-O Molds" by Kim B. Foglia.

Subject:
Biology
Life Science
Material Type:
Activity/Lab
Assessment
Lesson Plan
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Heather Netland
Date Added:
12/13/2011
Human Chromosome 2
Read the Fine Print
Educational Use
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In this video segment adapted from NOVA: Judgment Day: Intelligent Design on Trial, learn how modern genetics and molecular biology offer compelling support for evolution. The video features an interview with biologist Ken Miller.

Subject:
Anthropology
Genetics
Life Science
Social Science
Material Type:
Lecture
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
Vulcan Productions, Inc.
WGBH Educational Foundation
Date Added:
11/01/2007
An Interactive Introduction to Organismal and Molecular Biology
Conditional Remix & Share Permitted
CC BY-NC-SA
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Short Description:
This "textbook" is interactive, meaning that although each chapter has text, they also have interactive HTML5 content, such as quizzes, simulations, interactive videos, and images with clickable hotspots. Students receive instant feedback when they complete the interactive content, and therefore, can learn and check their understanding all in one place. The first unit introduces students to the nature of science, including scientific controversies, and information literacy, including how to analyze literature and identify stakeholders. Unit 2 is organismal biology, including carbon cycling and population growth, and unit 3 is molecular biology with a focus on gene expression.

Long Description:
This “textbook” is interactive, meaning that although each chapter has text, they also have interactive HTML5 content, such as quizzes, simulations, interactive videos, and images with clickable hotspots. Students receive instant feedback when they complete the interactive content, and therefore, can learn and check their understanding all in one place. I still consider this textbook to be fairly text-heavy and will continue to make it even more interactive content!

The image on the cover represents the creation of this book. I pulled most of the content from open resources, modified them, added questions, and now offer them for you to use!

I chose the content to align with two courses that I teach: environmental and organismal applications and biomedical applications. Unit 1 introduces students to science, which both courses use. Unit 2 covers content necessary for understanding conservation implications (the underlying theme of the course is de-extinction), and Unit 3 focuses on proteins so that students can understand the implications of modifying DNA (the underlying theme is CRISPR).

Please use this book as you see fit for your classes. I look forward to hearing how to make this book even more useful in the future!

Word Count: 27692

ISBN: 978-1-62610-106-7

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Subject:
Anatomy/Physiology
Arts and Humanities
Career and Technical Education
Ecology
English Language Arts
Environmental Studies
Life Science
Philosophy
Reading Literature
Social Science
Sociology
Zoology
Material Type:
Textbook
Provider:
Michigan State University
Date Added:
01/01/2021
An Interactive Introduction to Organismal and Molecular Biology, 2nd ed.
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating
0.0 stars

Short Description:
This "textbook" is interactive, meaning that although each chapter has text, they also have interactive HTML5 content, such as quizzes, simulations, interactive videos, and images with clickable hotspots. Students receive instant feedback when they complete the interactive content, and therefore, can learn and check their understanding all in one place. The first unit introduces students to the nature of science, including scientific controversies, and information literacy, including how to analyze literature and identify stakeholders. Unit 2 is organismal biology, including carbon cycling and population growth, and unit 3 is molecular biology with a focus on gene expression.

Long Description:
This “textbook” is interactive, meaning that although each chapter has text, they also have interactive HTML5 content, such as quizzes, simulations, interactive videos, and images with clickable hotspots. Students receive instant feedback when they complete the interactive content, and therefore, can learn and check their understanding all in one place. I still consider this textbook to be fairly text-heavy and will continue to make it even more interactive content!

The image on the cover represents the creation of this book. I pulled most of the content from open resources, modified them, added questions, and now offer them for you to use!

I chose the content to align with two courses that I teach: environmental and organismal applications and biomedical applications. Unit 1 introduces students to science, which both courses use. Unit 2 covers content necessary for understanding conservation implications (the underlying theme of the course is de-extinction), and Unit 3 focuses on proteins so that students can understand the implications of modifying DNA (the underlying theme is CRISPR).

Please use this book as you see fit for your classes. I look forward to hearing how to make this book even more useful in the future!

Word Count: 34749

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Subject:
Anatomy/Physiology
Arts and Humanities
Career and Technical Education
Ecology
English Language Arts
Environmental Studies
Life Science
Philosophy
Reading Literature
Social Science
Sociology
Zoology
Material Type:
Textbook
Provider:
Michigan State University
Author:
Andrea Bierema
Date Added:
08/01/2021
Introduction to Biology
Conditional Remix & Share Permitted
CC BY-NC-SA
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The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
7.012 focuses on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.
Acknowledgments
The study materials, problem sets, and quiz materials used during Fall 2004 for 7.012 include contributions from past instructors, teaching assistants, and other members of the MIT Biology Department affiliated with course #7.012. Since the following works have evolved over a period of many years, no single source can be attributed.

Subject:
Biology
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Chess, Andrew
Gardel, Claudette
Lander, Eric
Weinberg, Robert
Date Added:
09/01/2004
Introductory Biology
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CC BY-NC-SA
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7.016 Introductory Biology provides an introduction to fundamental principles of biochemistry, molecular biology, and genetics for understanding the functions of living systems. Taught for the first time in Fall 2013, this course covers examples of the use of chemical biology and twenty-first-century molecular genetics in understanding human health and therapeutic intervention.
The MIT Biology Department Introductory Biology courses 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.

Subject:
Applied Science
Biology
Genetics
Health, Medicine and Nursing
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Imperiali, Barbara
Martin, Adam
Ray, Diviya
Date Added:
09/01/2018
Introductory Biology
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating
0.0 stars

The MIT Biology Department core Introductory Biology courses, 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. The focus of 7.013 is on genomic approaches to human biology, including neuroscience, development, immunology, tissue repair and stem cells, tissue engineering, and infectious and inherited diseases, including cancer.

Subject:
Biology
Genetics
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Amon, Angelika
Ray, Diviya
Sive, Hazel
Date Added:
02/01/2018
Introductory Biology
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating
0.0 stars

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
7.014 focuses on the application of these fundamental principles, toward an understanding of microorganisms as geochemical agents responsible for the evolution and renewal of the biosphere and of their role in human health and disease.
Acknowledgements
The study materials, problem sets, and quiz materials used during Spring 2005 for 7.014 include contributions from past instructors, teaching assistants, and other members of the MIT Biology Department affiliated with course 7.014. Since the following works have evolved over a period of many years, no single source can be attributed.

Subject:
Biology
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Chisholm, Penny
Khodor, Julia
Mischke, Michelle
Walker, Graham
Date Added:
02/01/2005
Introductory Biology
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating
0.0 stars

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. 7.013 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), developmental biology, neurobiology and evolution.
Biological function at the molecular level is particularly emphasized in all courses and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.

Subject:
Biology
Genetics
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Jacks, Tyler
Sinha, Diviya
Sive, Hazel
Date Added:
02/01/2013
Investigating Characteristics of Enzymes and the Factors That Affect Their Function
Conditional Remix & Share Permitted
CC BY-NC-SA
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This classroom lab allows students to develop skills of the scientific method while exploring the characteristics of enzymes.

Subject:
Chemistry
Physical Science
Material Type:
Activity/Lab
Assessment
Lesson Plan
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Jen Vance
Date Added:
12/09/2011
Investigating Starch in Foods
Conditional Remix & Share Permitted
CC BY-NC-SA
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This activity is a classroom experiment where students gather data on which foods contain starch. They use observation and develop their own hypothesis to create a question they would like to discover about starches.

Subject:
Life Science
Nutrition
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Darlene Schleis
Date Added:
08/16/2012
Kimball's Biology Pages
Unrestricted Use
CC BY
Rating
0.0 stars

The pages represent an online biology textbook created by Professor John W. Kimball who taught at Harvard, Tufts, and Phillips Andover Academy before he retired. He now maintains this free biology book, constantly updated and set up for easy browsing and searching.

Subject:
Biology
Life Science
Material Type:
Textbook
Provider:
Kimball's Biology Pages
Author:
John W. Kimball
Date Added:
10/28/2006
Malnutrition, DNA Replication, Development, and Schizophrenia Homework Problem
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CC BY-NC-SA
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At the beginning of a DNA, DNA replication, and mitosis unit, students are given a short science news article summarizing a recent research paper. This assignment links the article to figures and key techniques from a related journal article, requiring students to apply and transfer the knowledge they gained in the unit.

Subject:
Life Science
Material Type:
Activity/Lab
Homework/Assignment
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Starting Point (SERC)
Author:
Debby Walser-Kuntz
Sarah Deel
Susan Singer
Date Added:
08/28/2012
Microbiology in Jeopardy
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CC BY-NC-SA
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This group learning activity involves students in an engaging review of concepts of microbiology. The review is set up as a power point presentation in the style of the "Jeopardy" gameshow where students groups compete against each other to answer review questions.

(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)

Subject:
Biology
Chemistry
Life Science
Physical Science
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Teach the Earth
Author:
Stephen C. Wagner, Stephen F. Austin State University
Date Added:
12/21/2019
Microbiology in Jeopardy
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating
0.0 stars

This group learning activity involves students in an engaging review of concepts of microbiology. The review is set up as a power point presentation in the style of the "Jeopardy" gameshow where students groups compete against each other to answer review questions.

Subject:
Chemistry
Geoscience
Life Science
Physical Science
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Stephen C. Wagner
Date Added:
11/06/2014
Molecular Biology for the Auditory System
Conditional Remix & Share Permitted
CC BY-NC-SA
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An introductory course in the molecular biology of the auditory system. First half focuses on human genetics and molecular biology, covering fundamentals of pedigree analysis, linkage analysis, molecular cloning, and gene analysis as well as ethical/legal issues, all in the context of an auditory disorder. Second half emphasizes molecular approaches to function and dysfunction of the cochlea, and is based on readings and discussion of research literature.

Subject:
Applied Science
Biology
Genetics
Health, Medicine and Nursing
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Cotanche, Doug
Giersch, Anne
Heller, Stefan
Kenna, Marley
Liberman, Charlie
Rehm, Heidi
Sewell, Bill
Zheng-Yi, Chen
Date Added:
09/01/2002
Molecular, Cellular, and Tissue Biomechanics
Conditional Remix & Share Permitted
CC BY-NC-SA
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0.0 stars

This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular to tissue or organ level.

Subject:
Applied Science
Biology
Engineering
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Grodzinsky, Alan
Kamm, Roger
Date Added:
02/01/2015
Molecular Mechanism of Homologous Recombination in Meiosis
Unrestricted Use
CC BY
Rating
0.0 stars

Instructional video on molecular mechanism of homologous recombination in meiosis.

Although textbooks describe this process and show illustrations, it is difficult to grasp without seeing a live demonstration.

Created for Biology 41 General Genetics at Tufts University.

Subject:
Biology
Genetics
Life Science
Material Type:
Simulation
Author:
Ekaterina V. Mirkin
Date Added:
06/02/2021
The Online Macromolecular Museum
Rating
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The Online Macromolecular Museum (OMM) is a site for the display and study of macromolecules. Macromolecular structures, as discovered by crystallographic or NMR methods, are scientific objects in much the same sense as fossil bones or dried specimens: they can be archived, studied, and displayed in aesthetically pleasing, educational exhibits. Hence, a museum seems an appropriate designation for the collection of displays that we are assembling. The OMM's exhibits are interactive tutorials on individual molecules in which hypertextual explanations of important biochemical features are linked to illustrative renderings of the molecule at hand.

Why devote a site to detailed visualizations of different macromolecules? In learning about the intricacies of life processes at the molecular level, it is important to understand how natural selection has fashioned the structure and chemistry of macromolecular machines to suit them for particular functions. This understanding is greatly facilitated by the visualization of 3-dimensional structure, when known. So, if static views of molecules (even in stereo) are worth a thousand words, then interactive animations of molecules should be worth much more. Indeed, we have found the types of displays represented here invaluable in gaining an appreciation for the details of key biochemical processes.

As Carl Brandon and John Tooze stated in their classic text, Introduction to Protein Structure:
"Molecular biology began some 40 years ago with the realization that structure was crucial for a proper understanding of function. Paradoxically, the dazzling achievements of molecular genetics and biochemistry led to the eclipse of structural studies. We believe the wheel has now come full circle, and those very achievements have increased the need for structural analysis at the same time that they have provided the means for it."

It is our opinion that structural analysis should extend into the classroom: as students learn about cellular mechanisms it is important that they study the chemistry of the molecular machines involved. These considerations have motivated the construction of the OMM.

The OMM is part of a collaborative effort by faculty and students interested in macromolecular structure-function relationships. The primary authors of some tutorials are students of David Marcey and he serves as author, co-author and site editor, and assumes all responsibility for content. Any criticisms, suggestions, comments, or questions should be sent to him at: marcey@callutheran.edu. All tutorials are copyrighted.

The OMM was started in 1996 for a Molecular Biology class at Kenyon College, where DM was a professor in the Biology Department (1990-1999). The OMM is now developed and housed at California Lutheran University, where DM has been a professor since 1999.

Subject:
Chemistry
Life Science
Physical Science
Material Type:
Activity/Lab
Diagram/Illustration
Homework/Assignment
Interactive
Lesson
Author:
David Marcey
Date Added:
09/28/2017