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Targeting the molecular origins of heterotopic ossification
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Heterotopic ossification (HO) is the growth of bone where it doesn’t belong, such as in muscle tissue HO is most often observed after joint surgery in patients with severe trauma and can cause swelling, pain, nerve compression, and other complications While effective treatment and prevention strategies are currently lacking researchers are beginning to zero in on the molecular pathways that trigger HO It all starts with hypoxia, a state of oxygen deprivation that accompanies tissue damage Hypoxia activates the protein HIF-1α In certain patients, HIF-1α acts as a gateway to HO in at least three ways By stimulating proteins that lay the groundwork for new bone and cartilage By promoting blood vessel formation And by suppressing a protein that normally limits bone growth Drugs that reduce hypoxia or block HIF-1α could therefore prove powerful helping to stop HO early in its development.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/27/2020
Trauma Counseling
Unrestricted Use
CC BY
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This brief book serves as an instructor for a self-help course that will be offered to persons who have been through a terrible experience. Once you find yourself in the position of supporting a person who has experienced trauma, the book walks you through the various steps that are needed of you.

Subject:
Social Work
Material Type:
Teaching/Learning Strategy
Author:
Lasarus Nghifindwako Hakwaake
Date Added:
11/11/2022
Trauma-Informed Care in Behavioral Health Services
Unrestricted Use
Public Domain
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Many individuals experience trauma during their lifetimes. Although many people exposed to trauma demonstrate few or no lingering symptoms, those individuals who have experienced repeated, chronic, or multiple traumas are more likely to exhibit pronounced symptoms and consequences, including substance abuse, mental illness, and health problems. Subsequently, trauma can significantly affect how an individual engages in major life areas as well as treatment. This TIP provides evidence-based and best practice information for behavioral health service providers and administrators who want to work more effectively with people who have been exposed to acute and chronic traumas and/or are at risk of developing traumatic stress reactions. Using key trauma-informed principles, this TIP addresses trauma-related prevention, intervention, and treatment issues and strategies in behavioral health services. The content is adaptable across behavioral health settings that service individuals, families, and communities—placing emphasis on the importance of coordinating as well as integrating services.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Textbook
Author:
Center For Substance Abuse Treatment Us
Date Added:
02/05/2021
Trauma and Children - Newborn to Two Years
Only Sharing Permitted
CC BY-NC-ND
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An article about how babies and toddlers are directly affected by trauma, trauma in the household, home or routine disruption, and how you can provide a supportive environment.

Subject:
Social Science
Material Type:
Reading
Date Added:
08/17/2016
Trauma and Resilience Among Displaced Populations
Unrestricted Use
CC BY
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Includes cases based on the author’s own 10-year experience working in emergency contexts with displaced populations in 11 countries across the world.
Focuses on the mental health of displaced populations from a uniquely psychological, sociocultural, and ecological perspective.
Provides practical applications for non-specialist professionals working with displaced populations in complex institutional systems.
Is an open access book.

Subject:
Social Science
Social Work
Material Type:
Textbook
Author:
Gail Theisen-Womersley
Date Added:
12/22/2021
Video Library: Northern California Training Academy
Only Sharing Permitted
CC BY-NC-ND
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This resource provides access to videos produced and/or used by the Northern California Training Academy to support training for child welfare practitioners. To learn more about the Academy, please visit humanservices.ucdavis.edu/academy.

Subject:
Career and Technical Education
Social Science
Material Type:
Activity/Lab
Homework/Assignment
Simulation
Date Added:
11/15/2017
A Zombie Got My Leg
Read the Fine Print
Educational Use
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Students experience the engineering design process as they design and construct lower-leg prostheses in response to a hypothetical zombie apocalypse scenario. Like the well-known Apollo 13 story during which engineers were challenged to fix the crippled spacecraft with limited supplies in order to save astronauts' lives, in this activity, students act as engineers during an imaginary disaster in which a group member's leg was amputated in order to survive a zombie attack. Building on what they learned and researched in the associated lesson, they design and fabricate a replacement prosthetic limb using given specific starting material and limited additional supplies, similar to how engineers design for individuals while working within constraints. A more-advanced scenario challenges students to design a prosthesis that is able to provide a more-specific movement function.

Subject:
Applied Science
Engineering
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Andrea Lee
Megan Ketchum
Date Added:
10/14/2015