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  • Biomedical
Digestion Simulation
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To reinforce students' understanding of the human digestion process, the functions of ... More

To reinforce students' understanding of the human digestion process, the functions of several stomach and small intestine fluids are analyzed, and the concept of simulation is introduced through a short, introductory demonstration of how these fluids work. Students learn what simulation means and how it relates to the engineering process, particularly in biomedical engineering. The teacher demo requires vinegar, baking soda, water and aspirin. Less

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Subject:
Engineering
Education
Life Science
Ecology
Forestry and Agriculture
Chemistry
Material Type:
Activities and Labs
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Integrated Teaching and Learning Program,
Jacob Crosby
Malinda Schaefer Zarske
TeachEngineering.org
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Disease and Society in America, Fall 2005
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This course examines the growing importance of medicine in culture, economics and ... More

This course examines the growing importance of medicine in culture, economics and politics. It uses an historical approach to examine the changing patterns of disease, the causes of morbidity and mortality, the evolution of medical theory and practice, the development of hospitals and the medical profession, the rise of the biomedical research industry, and the ethics of health care in America. Less

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Subject:
Economics
Material Type:
Full Course
Homework and Assignments
Lecture Notes
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Jones, David
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Engineering Bones
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Students extend their knowledge of the skeletal system to biomedical engineering design, ... More

Students extend their knowledge of the skeletal system to biomedical engineering design, specifically the concept of artificial limbs. Students relate the skeleton as a structural system, focusing on the leg as structural necessity. They learn about the design considerations involved in the creation of artificial limbs, including materials and sensors. Less

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Subject:
Engineering
Life Science
Physics
Material Type:
Activities and Labs
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Integrated Teaching and Learning Program,
Malinda Schaefer Zarske
Megan Podlogar
TeachEngineering.org
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Engineering the Heart: Heart Valves
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Students learn how healthy human heart valves function and the different diseases ... More

Students learn how healthy human heart valves function and the different diseases that can affect heart valves. They also learn about devices and procedures that biomedical engineers have designed to help people with damaged or diseased heart valves. Students learn about the pros and cons of different materials and how doctors choose which engineered artificial heart valves are appropriate for certain people. Less

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Subject:
Engineering
Health, Medicine and Nursing
Life Science
Material Type:
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Ben Terry
Brandi Briggs
Carleigh Samson
Integrated Teaching and Learning Program,
TeachEngineering.org
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Engineers Love Pizza, Too!
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In this service-learning engineering project, students follow the steps of the engineering ... More

In this service-learning engineering project, students follow the steps of the engineering design process to design an assistive eating device for a client. More specifically, they design a prototype device to help a young girl who has a medical condition that restricts the motion of her joints. Her wish is to eat her favorite food, pizza, without getting her nose wet. Students learn about arthrogryposis and how it affects the human body as they act as engineers to find a solution to this open-ended design challenge and build a working prototype. This project works even better if you arrange for a client in your own community. Less

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Subject:
Engineering
Education
Life Science
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Eszter Horanyi
Integrated Teaching and Learning Program,
Jonathan MacNeil
Malinda Zarske
M. Travis O'Hair
Stephanie Rivale, Brandi Briggs (This activity was taught at Skyline High School in Longmont, CO. A special thanks to Sarah Delaney and Jordian Summers for their help in developing this activity.)
TeachEngineering.org
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Feel Better Faster: All about Flow Rate
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All of us have felt sick at some point in our lives. ... More

All of us have felt sick at some point in our lives. Many times, we find ourselves asking, "What is the quickest way that I can start to feel better?" During this two-lesson unit, students study that question and determine which form of medicine delivery (pill, liquid, injection/shot) offers the fastest relief. This challenge question serves as a real-world context for learning all about flow rates. Students study how long various prescription methods take to introduce chemicals into our blood streams, as well as use flow rate to determine how increasing a person's heart rate can theoretically make medicines work more quickly. Students are introduced to engineering devices that simulate what occurs during the distribution of antibiotic cells in the body. Less

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Subject:
Engineering
Life Science
Mathematics
Physics
Material Type:
Instructional Material
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Michelle Woods
TeachEngineering.org
VU Bioengineering RET Program,
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Forced to Fracture
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Students learn how forces affect the human skeletal system through fractures and ... More

Students learn how forces affect the human skeletal system through fractures and why certain bones are more likely to break than others depending on their design and use in the body. They learn how engineers and doctors collaborate to design effective treatments with consideration for the location, fracture severity and patient age, as well as the use of biocompatible materials. Learning the lesson content prepares students for the associated activity in which they test small animal bones to failure and then design treatment repair plans. Less

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Subject:
Engineering
Education
Life Science
Physics
Material Type:
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Andrea Lee, Megan Ketchum
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
TeachEngineering.org
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The Fountain of Life: From Dolly to Customized Embryonic Stem Cells, Fall 2007
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" During development, the genetic content of each cell remains, with a ... More

" During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which have proved to involve reversible alterations to both DNA and to proteins that bind DNA, are known as epigenetic, to distinguish them from genetic alterations to DNA sequence. In this course we will explore such epigenetic changes and study different approaches that can return a differentiated cell to an embryonic state in a process referred to as epigenetic reprogramming, which will ultimately allow generation of patient-specific stem cells and application to regenerative therapy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching." Less

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Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Meissner, Alexander
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Genomic Medicine, Spring 2004
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This course reviews the key genomic technologies and computational approaches that are ... More

This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be? Less

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Subject:
Health, Medicine and Nursing
Genetics
Material Type:
Activities and Labs
Audio Lectures
Full Course
Homework and Assignments
Lecture Notes
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Kohane, Isaac
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The Heart of Our Cardiovascular System
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Students learn about the heart and its role at the center of ... More

Students learn about the heart and its role at the center of the human cardiovascular system. In the associated activity, students play out a scenario in which they are biomedical engineers asked to design artificial hearts. They learn about the path of blood flow through the heart and use that knowledge to evaluate designs of artificial hearts on the market. Less

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Subject:
Engineering
Life Science
Material Type:
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Angela D. Kolonich
Bio-Inspired Technology and Systems (BITS) RET,
TeachEngineering.org
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High Arches, Low Arches
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A main concern of shoe engineers is creating shoes that provide the ... More

A main concern of shoe engineers is creating shoes that provide the right amount of arch support to prevent (or fix) common gait misalignments that lead to injury. During this activity, students look at their own footprints and determine whether they have either of the two most prominent gait misalignments: overpronation (collapsing arches) or supination (high arches). Knowing the shape of a person's foot, and their natural arch movement is necessary to design shoes to fix these gain alignments. Less

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Subject:
Engineering
Life Science
Physics
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Eszter Horanyi
Integrated Teaching and Learning Program,
TeachEngineering.org
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Highlighting the Neuron
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In this lesson on the brain's neural networks, students investigate the structure ... More

In this lesson on the brain's neural networks, students investigate the structure and function of the neuron. They discover ways in which engineers apply this knowledge to the development of devices that can activate neurons. After a review of the nervous system—specifically its organs, tissue, and specialized cells, called neurons—students learn about the parts of the neuron. They explore the cell body, dendrites, axon and axon terminal, and learn how these structures enable neurons to send messages. They learn about the connections between engineering and other fields of study, and the importance of research, as they complete the lesson tasks. Less

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Subject:
Engineering
Life Science
Mathematics
Physics
Material Type:
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Janelle Orange
Robotics Engineering for Better Life and Sustainable Future RET,
TeachEngineering.org
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How Antibiotics Work
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Students are introduced to a challenge question. Towards answering the question, they ... More

Students are introduced to a challenge question. Towards answering the question, they generate ideas for what they need to know about medicines and how they move through our bodies, watch a few short videos to gain multiple perspectives, and then learn lecture material to obtain a basic understanding of how antibiotics kill bacteria in the human body. They learn why different forms of medicine (pill, liquid or shot) get into the blood stream at different speeds. Less

More
Subject:
Engineering
Life Science
Material Type:
Instructional Material
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Michelle Woods
TeachEngineering.org
VU Bioengineering RET Program,
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If You're Not Part of the Solution, You're Part of the Precipitate!
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Students continue the research begun in the associated lesson as if they ... More

Students continue the research begun in the associated lesson as if they were biomedical engineers working for a pharmaceutical company. Groups each perform a simple chemical reaction (to precipitate solid calcium out of solution) to observe what may occur when Osteopontin levels drop in the body. With this additional research, students determine potential health complications that might arise from a new drug that could reduce inflammatory pain in many patients, improving their quality of life. The goal of this activity is to illustrate biomedical engineering as medical problem solving, as well as emphasize the importance of maintaining normal body chemistry. Less

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Subject:
Engineering
Life Science
Chemistry
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Angela D. Kolonich
Bio-Inspired Technology and Systems (BITS) RET,
TeachEngineering.org
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Inside the DNA
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Students conduct their own research to discover and understand the methods designed ... More

Students conduct their own research to discover and understand the methods designed by engineers and used by scientists to analyze or validate the molecular structure of DNA, proteins and enzymes, as well as basic information about gel electrophoresis and DNA identification. In this computer-based activity, students investigate particular molecular imaging technologies, such as x-ray, atomic force microscopy, transmission electron microscopy, and create short PowerPoint presentations that address key points. The presentations include their own explanations of the difference between molecular imaging and gel electrophoresis. Less

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Subject:
Engineering
Life Science
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
TeachEngineering.org
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Let the Blood Flow
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Students work as biomedical engineers to find liquid solutions that can clear ... More

Students work as biomedical engineers to find liquid solutions that can clear away polyvinyl acetate polymer "blood clots" in model arteries (made of clear, flexible tubing). Teams create samples of the "blood clot" polymer with different concentrations to discover the concentration of the model clot and then test a variety of liquids to determine which most effectively breaks down the model blood clot. Students learn the importance of the testing phase in the engineering design process, because they are only given one chance to present the team's solution and apply it to the model blood clot. Less

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Subject:
Engineering
Life Science
Ecology
Forestry and Agriculture
Chemistry
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Azim Laiwalla, Ann McCabe, Carleigh Samson
Science and Engineering of the Environment of Los Angeles (SEE-LA) GK-12 Program,
TeachEngineering.org
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Living with Your Liver
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Students learn the function of the liver and how biomedical engineers can ... More

Students learn the function of the liver and how biomedical engineers can use liver regeneration to help people. Students test the effects of toxic chemicals on a beef liver by adding hydrogen peroxide to various liver and salt solutions. They observe, record and graph their results. Less

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Subject:
Engineering
Material Type:
Activities and Labs
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Malinda Schaefer Zarske
Megan Schroeder
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MRI Safety Grand Challenge
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Students are given an engineering challenge: A nearby hospital has just installed ... More

Students are given an engineering challenge: A nearby hospital has just installed a new magnetic resonance imaging facility that has the capacity to make 3D images of the brain and other body parts by exposing patients to a strong magnetic field. The hospital wishes for its entire staff to have a clear understanding of the risks involved in working near a strong magnetic field and a basic understanding of why those risks occur. Your task is to develop a presentation or pamphlet explaining the risks, the physics behind those risks, and the safety precautions to be taken by all staff members. This 10-lesson/4-activity unit was designed to provide hands-on activities to teach end-of-year electricity and magnetism topics to a first-year accelerated or AP physics class. Students learn about and then apply the following science concepts to solve the challenge: magnetic force, magnetic moments and torque, the Biot-Savart law, Ampere's law and Faraday's law. This module is built around the Legacy Cycle, a format that incorporates findings from educational research on how people best learn. Less

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Subject:
Engineering
Life Science
Chemistry
Physics
Material Type:
Instructional Material
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Eric Appelt
Meghan Murphy
TeachEngineering.org
VU Bioengineering RET Program,
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Making Model Microfluidic Devices Using JELL-O
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Students create large-scale models of microfluidic devices using a process similar to ... More

Students create large-scale models of microfluidic devices using a process similar to that of the PDMS and plasma bonding that is used in the creation of lab-on-a-chip devices. They use disposable foam plates, plastic bendable straws and gelatin dessert mix. After the molds have hardened overnight, they use plastic syringes to inject their model devices with colored fluid to test various flow rates. From what they learn, students are able to answer the challenge question presented in lesson 1 of this unit by writing individual explanation statements. Less

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Subject:
Engineering
Life Science
Material Type:
Activities and Labs
Instructional Material
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Michelle Woods (primary author)
TeachEngineering.org
VU Bioengineering RET Program,
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Measuring Our Muscles
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Student teams build model hand dynamometers used to measure grip strengths of ... More

Student teams build model hand dynamometers used to measure grip strengths of people recovering from sports injuries. They use their models to measure how much force their classmates muscles are capable of producing, and analyze the data to determine factors that influence a person's grip strength. They use this information to produce a recommendation of a hand dynamometer design for a medical office specializing in physical therapy. They also consider the many other ways grip strength data is used by engineers to design everyday products. Less

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Subject:
Engineering
Material Type:
Activities and Labs
Lesson Plans
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Jake Lewis
Malinda Schaefer Zarske
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